1.
Chem Commun (Camb)
; 59(74): 11065-11068, 2023 Sep 14.
Article
in English
| MEDLINE
| ID: mdl-37644820
ABSTRACT
α-Substituted methylsulfinamide are prepared through the homologation of electrophilic N-sulfinylamines with Li-CHXY reagents. The transformation takes place under full chemocontrol and exhibits good flexibility for preparing both N-aryl and N-alkyl analogues. Various sensitive functionalities can be accommodated on the starting materials, thus documenting a wide reaction scope.