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1.
Aust N Z J Psychiatry ; 58(1): 82-91, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37122137

ABSTRACT

OBJECTIVE: To explore the views of psychiatrists (including trainees) regarding the current state and future direction of specialist mental health and addictions services in Aotearoa New Zealand. METHODS: Psychiatrists and trainee psychiatrists (registrars) in Aotearoa New Zealand were surveyed in August 2021. Of 879 eligible doctors, 540 participated (83% qualified and 17% trainee psychiatrists), a response rate of over 60%. Data were analysed quantitatively and with content analysis. RESULTS: Psychiatrists thought specialist mental health and addictions services had been neglected during recent reforms, with 94% believing current resourcing was insufficient, and only 3% considering future planning was heading in the right direction. The demand and complexity of on-call work had markedly increased in the preceding 2 years. Ninety-eight percent reported that people needing specialist treatment were often (85%) or sometimes (13%) unable to access the right care due to resourcing constraints. The pressures were similar across sub-specialties. A key theme was the distress (sometimes termed 'moral injury') experienced by psychiatrists unable to provide adequate care due to resource limitations, 'knowing what would be a good thing to do and being unable to do it . . . is soul destroying'. Recommendations were made for addressing workforce, service design and wider issues. CONCLUSION: Most psychiatrists in Aotearoa New Zealand believe the mental health system is not currently fit for purpose and that it is not heading in the right direction. Remedies include urgently addressing identified staffing challenges and boosting designated funding to adequately care for the 5% of New Zealanders with severe mental health and addiction needs.


Subject(s)
Health Workforce , Mental Health Services , Psychiatry , Humans , New Zealand , Psychiatrists
2.
J Hand Surg Am ; 48(8): 832.e1-832.e6, 2023 08.
Article in English | MEDLINE | ID: mdl-35414448

ABSTRACT

PURPOSE: The aim of this study was to determine whether the clinical results of zone I flexor digitorum profundus (FDP) tendon injuries managed with acute surgical repair are comparable to the clinical results of those managed without repair (eg, primary FDP excision or observation). METHODS: Patients aged ≥18 years presenting to a level 1 trauma center between 2015 and 2020 with zone I FDP tendon injury were identified with retrospective chart review. We assessed the following data: age, sex, physical therapy visits, surgical intervention, surgical complications (including infection, repeat surgery after the primary intervention, and rupture of repair), and patient-reported outcomes measurement information system scores. RESULTS: Twenty-six patients met the inclusion criteria. Group 1 (N = 15 patients, 23 fingers) patients were treated with acute surgical repair. Group 2 (N = 11 patients, 11 fingers) patients were managed without surgical repair, including FDP excision (N = 7) or observation alone (N = 4). In group 1, the average distance from the distal palmar crease to fingertip at the final follow-up was 1.6 cm (range, 0-4 cm). Fourteen of the 15 patients participated in >3 therapy visits. The following complications occurred: 4 fingers with rerupture (2 patients), 4 fingers with surgical wound dehiscence (2 patients), 3 infections (2 patients), and 4 repeat surgeries for these complications. In group 2, the average distance from the distal palmar crease to fingertip at the final follow-up was 1.1 cm (range, 0.5-3 cm). There were no infections, episodes of wound dehiscence, or repeat surgeries. At the final follow-up, both groups showed clinically meaningful improvement on Patient Reported Outcomes Measurement Information System (PROMIS) upper extremity, pain interference, and physical function scores, with similar PROMIS domain scores between groups. CONCLUSIONS: Patients treated without FDP tendon repair had similar outcomes to, and fewer complications than, patients treated with acute tendon repair. Our data suggest that the notable commitment of health care costs, time, and adherence to protocols/restrictions after surgical repair may not confer functional benefit. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.


Subject(s)
Finger Injuries , Tendon Injuries , Humans , Adolescent , Adult , Retrospective Studies , Finger Injuries/surgery , Tendon Injuries/surgery , Muscle, Skeletal , Fingers
3.
Front Psychiatry ; 11: 419, 2020.
Article in English | MEDLINE | ID: mdl-32477191

ABSTRACT

BACKGROUND: Bariatric surgery is seldom accessed by people with serious mental illness, despite high rates of obesity in this population. It is sometimes assumed that patients with complex psychiatric histories will have poor post-surgical weight loss or exacerbation of psychiatric symptoms, although this is unsubstantiated. OBJECTIVES: A qualitative descriptive study to explore personal experiences and the impact of bariatric surgery on physical and mental well-being and life-quality in individuals with serious mental illness. METHODS: Nine adults with a history of bariatric surgery and concurrent severe depressive disorder, bipolar disorder, or schizoaffective disorder were interviewed about their experiences of bariatric surgery and its outcomes using semi-structured interview schedules. Data were transcribed and inductive thematic analysis undertaken. RESULTS: Five broad themes emerged: (1) surgery was highly effective for weight loss, and resulted in subjective improvements in physical health, quality of life, and mental health described as being able to live a life; (2) recovering from surgery was a tough road, notably in the post-operative period where negative sequelae often anteceded benefits; (3) post-operative support was important, but sometimes insufficient, including from families, mental health services, and surgical teams; (4) most considered surgery life-changing, recommending it to others with mental illness and obesity, two had different experiences; (5) participants considered it discriminatory that people with mental illness were not referred or declined weight loss surgery. CONCLUSIONS: Participants benefited from bariatric surgery and felt it should be offered to others with mental illness, but with additional care and support.

4.
Australas Psychiatry ; 27(3): 215-218, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30379082

ABSTRACT

OBJECTIVE: To explore key sources of stress experienced during training by psychiatry registrars and identify which coping strategies they found helpful or unhelpful. METHOD: We used three data sources: a) 'stress' vignettes written by Stage 3 trainees; b) minutes of regular registrar meetings; c) focus groups. We analysed these using abbreviated grounded theory, generating themes. RESULTS: The main sources of stress during training were disempowerment, adverse events, difficult supervision and cultural perspectives. Other themes included difficulties in after-hours work, and organisational issues. Stressors may differ in impact according to training stage. Peer support and a good supervisory relationship reduced stress. Conversely, a poor supervisory relationship compounded stress. Trainees were motivated to address modifiable problems. CONCLUSIONS: A variety of stressors influence training at all stages. Trainees, the College and employers each have a role in promoting trainee welfare. Interlinking cultural dimensions are not currently addressed in the training curriculum and require attention. A good supervisory relationship can buffer many stressors for trainees.


Subject(s)
Adaptation, Psychological , Health Personnel/psychology , Occupational Stress , Psychiatry/education , Focus Groups , Humans , New Zealand
5.
BMC Psychiatry ; 18(1): 300, 2018 09 18.
Article in English | MEDLINE | ID: mdl-30227840

ABSTRACT

BACKGROUND: Obesity is a significant problem for people with serious mental illness. We aimed to consider body size from the perspective of long-stay psychiatric inpatients, focussing on: weight gain and its causes and impacts; diet and physical activity; and the perceived ability to make meaningful change in these domains. METHOD: A mixed methods study with 51 long-term psychiatric forensic and rehabilitation inpatients using semi-structured interviews combined with biometric and demographic data. RESULTS: 94% of participants were overweight or obese (mean BMI 35.3, SD 8.1). They were concerned about their weight, with 75% of them attempting to lose weight. Qualitative responses indicated low personal effectiveness and self-stigmatisation. Participants viewed their weight gain as something 'done to them' through medication, hospitalisation and leave restrictions. A prevailing theme was that institutional constraints made it difficult to live a healthy life (just the way the system is). Many had an external locus of control, viewing weight loss as desirable but unachievable, inhibited by environmental factors and requiring a quantum of motivation they found hard to muster. Despite this, participants were thoughtful and interested, had sound ideas for weight loss, and wished to be engaged in a shared endeavour to achieve better health outcomes. Consulting people as experts on their experiences, preferences, and goals may help develop new solutions, remove unidentified barriers, and improve motivation. CONCLUSIONS: The importance of an individualised, multifactorial approach in weight loss programmes for this group was clear. Patient-led ideas and co-design should be key principles in programme and environmental design.


Subject(s)
Body Image/psychology , Diet/psychology , Exercise/psychology , Inpatients/psychology , Overweight/psychology , Adult , Female , Humans , Male , Motivation , Obesity/psychology , Perception , Personal Satisfaction , Qualitative Research , Research Design , Time Factors , Weight Gain , Weight Loss/physiology
7.
J Affect Disord ; 208: 272-277, 2017 Jan 15.
Article in English | MEDLINE | ID: mdl-27794250

ABSTRACT

BACKGROUND: Crying, a complex neurobiological behavior with psychosocial and communication features, has been little studied in relationship to the menstrual cycle. METHODS: In the Mood and Daily Life study (MiDL), a community sample of Canadian women aged 18-43 years, n=76, recorded crying proneness and crying frequency daily for six months along with menstrual cycle phase information. RESULTS: Crying proneness was most likely during the premenstruum, a little less likely during menses and least likely during the mid-cycle phase, with statistically significant differences although the magnitude of these differences were small. By contrast, actual crying did not differ between the three menstrual cycle phases. Oral contraceptive use did not alter the relationship between menstrual cycle phase and either crying variable. A wide range of menstrual cycle phase - crying proneness patterns were seen with visual inspection of the individual women's line graphs. LIMITATIONS: timing of ovulation was not ascertained. Using a three phase menstrual cycle division precluded separate late follicular and early luteal data analysis. The sample size was inadequate for a robust statistical test of actual crying. CONCLUSIONS: reproductive aged women as a group report feeling more like crying premenstrually but may not actually cry more during this menstrual cycle phase. Individual patterns vary substantially. Oral contraceptive use did not affect these relationships. Suggestions for future research are included.


Subject(s)
Crying/physiology , Menstrual Cycle/psychology , Adolescent , Adult , Affect , Contraceptives, Oral , Female , Humans , Self Report , Young Adult
8.
Sleep Med ; 16(10): 1217-24, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26429749

ABSTRACT

BACKGROUND: Sleep and mood disturbances in women have often been linked to the menstrual cycle, implying an ovarian hormonal causation. However, most studies in this area have used self-reported menstrual cycle phase rather than direct measurement of ovarian hormone concentrations. Further, many studies have focused primarily on peri- and postmenopausal populations reporting clinical sleep difficulty. In this study, we examined the associations among sleep quality, mood, and ovarian hormone concentration in a random sample of community-dwelling, nonclinical women of reproductive age. METHODS: Our sample consisted of 19 non-help-seeking women aged 18-43 years, each contributing an average of 39.5 nights of data. Over the 42 days of the study, we collected self-reported and actigraphic sleep-quality data, concentrations of urinary estrogen and progesterone metabolites (estrone-3-glucuronide (E1G) and pregnanediol-3-glucuronide [PdG], respectively), and daily mood ratings. Linear-mixed models were used to estimate associations, clustering longitudinal observations by the participant. RESULTS: We found a significant positive association between Sleep Efficiency and E1G, and a significant negative association between Sleep Efficiency and PdG. Otherwise, the self-reported and actigraphic sleep measures were not associated with ovarian hormone concentrations. Self-reported sleep was strongly associated with mood, whereas actigraphic sleep was associated with only two of the 11 individual mood items, "Feeling on Top of Things" and "Difficulty Coping." CONCLUSIONS: In this community sample of women of reproductive age, ovarian hormones play little, if any, role in day-to-day sleep quality. Our findings additionally highlight the different associations that self-reported and actigraphic sleep show with hormones and mood.


Subject(s)
Affect , Estrone/analogs & derivatives , Pregnanediol/analogs & derivatives , Sleep/physiology , Actigraphy , Adolescent , Adult , Affect/physiology , Estrone/urine , Female , Humans , Pregnanediol/urine , Self Report , Young Adult
9.
Int Clin Psychopharmacol ; 30(4): 193-201, 2015 Jul.
Article in English | MEDLINE | ID: mdl-25918885

ABSTRACT

Given the longstanding controversy about hypnosedative use, we aimed to investigate the attitudes of prescribing psychiatrists and service users towards long-term use of hypnosedative medication, and their perceptions of barriers to evidence-based nonmedication alternatives. Qualitative data from focus groups in Aotearoa/NZ were analysed thematically. A novel research design involved a service user researcher contributing throughout the research design and process. Service users and psychiatrists met to discuss each other's views, initially separately, and subsequently together. Analysis of the data identified four key themes: the challenge, for both parties, of sleep disturbance among service users with mental health problems; the conceptual and ethical conflicts for service users and psychiatrists in managing this challenge; the significant barriers to service users accessing evidence-based nonmedication alternatives; and the initial sense of disempowerment, shared by both service users and psychiatrists, which was transformed during the research process. Our results raise questions about the relevance of the existing guidelines for this group of service users, highlight the resource and time pressures that discourage participants from embarking on withdrawal regimes and education programmes on alternatives, highlight the lack of knowledge about alternatives and reflect the complex interaction between sleep and mental health problems, which poses a significant dilemma for service users and psychiatrists.


Subject(s)
Attitude of Health Personnel , Health Knowledge, Attitudes, Practice , Hypnotics and Sedatives/administration & dosage , Practice Patterns, Physicians' , Sleep Initiation and Maintenance Disorders/drug therapy , Sleep/drug effects , Access to Information , Complementary Therapies , Conflict, Psychological , Consumer Health Information , Drug Administration Schedule , Drug Prescriptions , Drug Utilization Review , Female , Focus Groups , Humans , Hypnotics and Sedatives/adverse effects , Male , Mental Health , New Zealand , Patient Education as Topic , Perception , Qualitative Research , Risk Assessment , Risk Factors , Sleep Initiation and Maintenance Disorders/diagnosis , Sleep Initiation and Maintenance Disorders/physiopathology , Time Factors , Treatment Outcome
10.
Sleep Med ; 16(4): 489-95, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25747332

ABSTRACT

OBJECTIVE: This study aimed to assess the temporal relationship of subjective sleep quality to menstrual cycle phase in a community (non help-seeking) sample of adult women over six months. Previous work has produced contradictory results and often used student samples. PATIENTS/METHODS: This was a cohort study, using daily electronic data collection in the Greater Toronto Area, Ontario, Canada; 76 women aged 18-42 years recruited by random digit telephone dialing, recorded mood, sleep quality, and other health variables on a daily basis for 24 weeks. RESULTS: Using linear mixed models, we assessed the relationship between subjective sleep quality and three menstrual cycle phases (menses, premenstrual and midcycle) over 395 cycles. Premenstrual sleep quality was poorer than during the rest of the cycle, with a mean difference of 1.32 between premenstrual and midcycle reference phase, on a 1-100 quality scale (higher score denotes poorer quality). This difference held when the independent variables of daily exercise and physical health were added to the model; it became non-significant when perceived stress and later, social support were also added to the model. CONCLUSIONS: Sleep quality in adult non-help seeking women is statistically poorer in the premenstruum but the size of the difference is of little clinical significance and was no longer statistically significant with inclusion of the potentially confounding variables, perceived stress and social support.


Subject(s)
Menstrual Cycle , Sleep , Adolescent , Adult , Cohort Studies , Female , Humans , Menstrual Cycle/physiology , Menstruation/physiology , Sleep/physiology , Surveys and Questionnaires , Young Adult
11.
J Psychiatr Pract ; 20(3): 188-95, 2014 May.
Article in English | MEDLINE | ID: mdl-24847992

ABSTRACT

The optimal management of sleep problems is a significant challenge, particularly in patients with psychiatric illness, because disturbed sleep is a known risk factor for relapse. This study used the short Dysfunctional Beliefs and Attitudes Scale to assess beliefs about sleep in adults with acute psychiatric disorders (N=100) recruited from inpatient and outpatient clinics. The subjects showed highly dysfunctional beliefs and attitudes about sleep and held diverse opinions about, but had low confidence in, their own capacity for optimal sleep management. They did not report excessive daytime sleepiness. We conclude that individuals with acute psychiatric illness worry significantly about their sleep and hold more dysfunctional beliefs about sleep than people without psychiatric illness. The absence of excessive daytime sleepiness in this sample, although counterintuitive, is consistent with findings in other studies. Given that two thirds of the sample expressed interest in non-pharmacological strategies to better manage their sleep problems, cognitive reshaping therapies appear to have clinical potential as alternatives to hypnosedative medication once a comprehensive sleep workup has excluded a physical sleep disorder such as obstructive sleep apnea. Dysfunctional beliefs and high concern about sleep offer potential targets for psychotherapy.


Subject(s)
Cognitive Behavioral Therapy/methods , Culture , Hypnotics and Sedatives/therapeutic use , Mental Disorders , Sleep Wake Disorders , Adult , Attitude to Health , Cognition , Cross-Sectional Studies , Disease Management , Female , Humans , Male , Mental Disorders/complications , Mental Disorders/diagnosis , Mental Disorders/epidemiology , Mental Disorders/psychology , Mental Disorders/therapy , Mentally Ill Persons/psychology , Middle Aged , New Zealand/epidemiology , Psychiatric Status Rating Scales , Risk Factors , Secondary Prevention/methods , Sleep Wake Disorders/diagnosis , Sleep Wake Disorders/etiology , Sleep Wake Disorders/psychology , Sleep Wake Disorders/therapy
13.
Int Clin Psychopharmacol ; 28(4): 157-63, 2013 Jul.
Article in English | MEDLINE | ID: mdl-23680995

ABSTRACT

The objective of this study was to describe hypnosedative (HS) prescribing patterns in a typical sample of psychiatric outpatients. Prescription information was extracted from the clinical records of all current outpatients at two New Zealand public mental health centres. This included the type and duration of HS use and documentation of a clinical review of longstanding (>3 months) use, patient sex, age and ICD10 diagnoses. One-third of the patients (35.2%) were prescribed at least one HS; this was longstanding in two-thirds (69%). One in 10 had a coprescription of more than one HS drug. HS use was related to female sex and diagnosis, being more common among patients with nonpsychotic than psychotic disorders and very infrequent in patients on clozapine. In most longstanding cases, a clinical review had been documented. The logistic regression confirmed female sex, diagnosis and clozapine all as independent predictors of HS prescription. HS prescribing in psychiatric illness is more common than in the general population, often longstanding, with polypharmacy being common. The frequent use of antipsychotic drugs as HSs is of concern, given their side-effect profile. As there are risks involved with longstanding HS use, a better rationale for the role of medication in the management of sleep problems in psychiatric disorders is needed.


Subject(s)
Antipsychotic Agents/therapeutic use , Hypnotics and Sedatives/therapeutic use , Mental Disorders/drug therapy , Practice Patterns, Physicians' , Adult , Ambulatory Care Facilities , Community Mental Health Services , Diagnostic and Statistical Manual of Mental Disorders , Drug Prescriptions , Drug Therapy, Combination , Female , Humans , Male , Medical Records , Middle Aged , Mood Disorders/drug therapy , New Zealand , Retrospective Studies , Schizophrenia/drug therapy , Sex Characteristics
14.
Psychother Psychosom ; 82(1): 53-60, 2013.
Article in English | MEDLINE | ID: mdl-23147261

ABSTRACT

BACKGROUND: Premenstrual mood symptoms are considered common in women, but such prevailing attitudes are shaped by social expectations about gender, emotionality and hormonal influences. There are few prospective, community studies of women reporting mood data from all phases of the menstrual cycle (MC). We aimed (i) to analyze daily mood data over 6 months for MC phase cyclicity and (ii) to compare MC phase influences on a woman's daily mood with that attributable to key alternate explanatory variables (physical health, perceived stress and social support). METHOD: A random sample of Canadian women aged 18-40 years collected mood and health data daily over 6 months, using telemetry, producing 395 complete MCs for analysis. RESULTS: Only half the individual mood items showed any MC phase association; these links were either with the menses phase alone or the menses plus the premenstrual phase. With one exception, the association was not solely premenstrual. The menses-follicular-luteal MC division gave similar results. Less than 0.5% of the women's individual periodogram records for each mood item showed MC entrainment. Physical health, perceived stress and social support were much stronger predictors of mood (p < 0.0001 in each case) than MC phase. CONCLUSIONS: The results of this study do not support the widespread idea of specific premenstrual dysphoria in women. Daily physical health status, perceived stress and social support explain daily mood better than MC phase.


Subject(s)
Affect/physiology , Menstrual Cycle/psychology , Premenstrual Syndrome/epidemiology , Adolescent , Adult , Female , Humans , Prospective Studies , Social Support , Stress, Psychological/psychology , Time Factors , Young Adult
15.
Gend Med ; 9(5): 361-84, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23036262

ABSTRACT

BACKGROUND: The human menstrual cycle (MC) has historically been the focus of myth and misinformation, leading to ideas that constrain women's activities. OBJECTIVES: We wished to examine one pervasive idea, that the MC is a cause of negative mood, by studying the scientific literature as a whole. We briefly reviewed the history of the idea of premenstrual syndrome and undertook a systematic review of quality studies. METHODS: We searched PubMed, PsycINFO, and article bibliographies for published studies using non-help-seeking samples with daily mood data collected prospectively for a minimum of 1 complete MC. We critiqued their methodologies and tabulated the key findings. RESULTS: Of 47 English language studies identified, 18 (38.3%) found no association of mood with any MC phase; 18 found an association of negative mood in the premenstrual phase combined with another MC phase; and only 7 (14.9%) found an association of negative mood and the premenstrual phase. Finally, the remaining 4 studies (8.5%) showed an association between negative mood and a non-premenstrual phase. Considering the only 41 adequately powered studies, the same phase links were reported by 36.6%, 41.5%, and 13.5% of studies, respectively. Their diversity of methods (sampling, instruments, and cycle phase definitions) precluded a meta-analysis. CONCLUSIONS: Taken together, these studies failed to provide clear evidence in support of the existence of a specific premenstrual negative mood syndrome in the general population. This puzzlingly widespread belief needs challenging, as it perpetuates negative concepts linking female reproduction with negative emotionality.


Subject(s)
Affect , Menstrual Cycle/psychology , Mood Disorders/etiology , Premenstrual Syndrome/psychology , Female , Humans , Prospective Studies
16.
Horm Behav ; 62(4): 448-54, 2012 Sep.
Article in English | MEDLINE | ID: mdl-22902271

ABSTRACT

Fluctuations in ovarian hormones across the menstrual cycle have long been considered a determinant of mood in women. The majority of studies, however, use menstrual cycle phase as proxy for hormone levels. We measured ovarian hormone levels directly in order to examine the relationship between daily hormone levels and mood in non-help-seeking women. Participants (n=19) provided daily information about their positive and negative moods, and collected their first morning-voided urine for 42days, which was analyzed for estrogen and progesterone metabolites (E1G and PdG). The independent contributions of daily E1G, PdG, stress, physical health, and weekly social support, were calculated for 12 daily mood items, and composite measures of positive and negative mood items, using linear mixed models. E1G or PdG contributed to few mood items: E1G measured 2days prior contributed negatively to the model for Motivation, while E1G measured 3days prior contributed negatively to Getting Along with Others, and E1G measured 4days prior contributed negatively to Anxiety. PdG, measured the same day and 1day prior, contributed positively to the models of Irritability, and PdG measured 5days prior contributed positively to Difficulty Coping. By contrast, the variables stress and physical health contributed significantly to all the mood items, as well as both composite positive and negative mood measures. These findings demonstrate that, compared to stress and physical health, ovarian hormones make only a small contribution to daily mood. Thus, fluctuations in ovarian hormones do not contribute significantly to daily mood in healthy women.


Subject(s)
Affect/physiology , Gonadal Steroid Hormones/physiology , Adolescent , Adult , Affect/drug effects , Circadian Rhythm/physiology , Estrogens/metabolism , Estrogens/urine , Female , Gonadal Steroid Hormones/pharmacology , Gonadal Steroid Hormones/urine , Humans , Menstrual Cycle/psychology , Menstrual Cycle/urine , Mood Disorders/etiology , Mood Disorders/urine , Ovary/metabolism , Progesterone/metabolism , Progesterone/urine , Psychology , Socioeconomic Factors , Surveys and Questionnaires , Young Adult
17.
J Nerv Ment Dis ; 200(1): 83-7, 2012 Jan.
Article in English | MEDLINE | ID: mdl-22210367

ABSTRACT

Adult patients (N = 100) being treated for acute psychiatric illness were interviewed about their sleep problems and attitudes toward available treatments. Most (74%) were using at least one prescribed psychotropic drug with hypnotic or sedative effects. Participants prescribed three or more drugs were less likely to name them correctly compared with those prescribed less. One quarter (24%) did not know that they were on a hypnosedative; more than half of those not prescribed a hypnosedative thought they were. Most participants found their medication effective; however, 54% wished to discontinue it. Two fifths of zopiclone users had been using it for more than 12 months. Although subjective sleep problems are very common in this patient group, they have limited accurate knowledge about their medication treatments. Many want to try alternative nonpharmacological ways to manage their sleep problems.


Subject(s)
Azabicyclo Compounds/therapeutic use , Health Knowledge, Attitudes, Practice , Hypnotics and Sedatives/therapeutic use , Piperazines/therapeutic use , Prescription Drugs/therapeutic use , Psychotropic Drugs/therapeutic use , Sleep Wake Disorders/drug therapy , Acute Disease , Adult , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , New Zealand , Polypharmacy , Surveys and Questionnaires , Treatment Outcome , Young Adult
18.
Adv Psychosom Med ; 32: 35-57, 2012.
Article in English | MEDLINE | ID: mdl-22056897

ABSTRACT

Childhood adversity increases risk of psychological and physical disorders. The comprehensive psychosomatic assessment of an individual's vulnerability to illness includes the evaluation of early life events, especially exposure to physical, emotional, sexual abuse and neglect. Many self-report and observer-rated instruments are now available to aid this evaluation and increase its validity. The authors review the features and limitations of published tools, and recommend which to choose for clinical and research purposes.


Subject(s)
Child Abuse, Sexual/diagnosis , Child Abuse/diagnosis , Life Change Events , Personality Assessment , Psychophysiologic Disorders/diagnosis , Psychophysiologic Disorders/psychology , Adolescent , Adult , Child , Child Abuse/psychology , Child Abuse, Sexual/psychology , Child, Preschool , Female , Humans , Male , Object Attachment , Resilience, Psychological , Risk Factors , Stress Disorders, Post-Traumatic/diagnosis , Stress Disorders, Post-Traumatic/psychology , Young Adult
19.
Gend Med ; 8(5): 283-99, 2011 Oct.
Article in English | MEDLINE | ID: mdl-21907634

ABSTRACT

Estrogens and progestagens (ovarian steroids) not only play an important a role in sexual behavior and reproduction, but they are involved in the development, regulation, and function of all body systems, including aging, sleep, pain, pharmacodynamics, immune response, and cognition. They are essential to the maintenance of cardiovascular, renal, mental, and bone health. Often, their effects are positive and their absence, negative. However, in certain contexts they can promote the development of cancers and neurologic conditions. Finally, ovarian steroids can even affect the response to pharmacologic treatments for many diseases. Given their central role in human biology, it is essential to be able to accurately determine the circulating levels of these hormones. To facilitate such endeavors, this review provides a comprehensive overview of the role of ovarian steroids in normal and abnormal physiology, primarily in women. It discusses the sensitivity, specificity, and precision of the most commonly used assays for estrogens and progestagens: bioassay, immunoassay, and mass spectrophotometry. Examples of how each of these assays has been used with samples taken from serum, urine, and saliva are provided. Strengths and limitations of each method are discussed.


Subject(s)
Estrogens/analysis , Progestins/analysis , Biological Assay , Estrogens/blood , Estrogens/urine , Humans , Immunoassay , Mass Spectrometry , Progestins/blood , Progestins/urine , Saliva/chemistry
20.
Arch Womens Ment Health ; 14(4): 325-33, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21695590

ABSTRACT

Perinatal depression currently receives considerable attention, but not all perinatal women presenting for psychiatric care are depressed. The Edinburgh Postnatal Depression Scale (EPDS) is now routinely administered, but high scores are interpreted as evidence for depressive illness only. This study examined psychiatric diagnoses and mean EPDS scores among perinatal women at a tertiary center. Women accessing care between March 2006 and June 2008 completed a clinical diagnostic interview and the EPDS. Mean EPDS scores were calculated for each psychiatric diagnosis; sensitivity and specificity were calculated for major depressive episode (MDE) and generalized anxiety disorder (GAD). The majority of the sample (N = 91), 49.5%, had GAD comorbid with MDE or another anxiety disorder, followed by MDE (38.5%) comorbid with an anxiety disorder. One third (29.7%) met criteria for MDE and GAD. Only 3.3% had MDE alone and 5.5% had GAD alone. Half the sample (50.5%) had more than one psychiatric disorder. Mean EPDS scores exceeded 11 for the majority of diagnostic groups. Sensitivity of the EPDS for MDE was 0.78 and 0.70 for GAD. Most women had an anxiety disorder and met criteria for more than one psychiatric disorder. Mean EPDS scores were consistently high. Sensitivity of the EPDS for MDE and GAD was comparable.


Subject(s)
Anxiety Disorders/epidemiology , Depression, Postpartum/diagnosis , Depression, Postpartum/epidemiology , Perinatal Care/methods , Referral and Consultation/statistics & numerical data , Women's Health , Adult , Anxiety Disorders/diagnosis , Canada/epidemiology , Comorbidity , Depressive Disorder/diagnosis , Depressive Disorder/epidemiology , Female , Humans , Mood Disorders/diagnosis , Mood Disorders/epidemiology , Prevalence , Risk Factors , Stress, Psychological/diagnosis , Stress, Psychological/epidemiology , Young Adult
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