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1.
SAGE Open Med Case Rep ; 7: 2050313X19847801, 2019.
Article in English | MEDLINE | ID: mdl-31105953

ABSTRACT

Epithelioid sarcoma is a very rare tumor, comprising less than 1% of all soft tissue sarcoma. Due to its rarity and benign presentation, it is often misdiagnosed. We present a case of epithelioid sarcoma mimicking coronary artery bypass grafting post-operative keloid. Current literature suggests the management for epithelioid sarcoma to include surgery and adjuvant radiation. In this patient, chest wall reconstruction was done using titanium mesh and muscle flaps. Post-operative radiation was given and computerized tomography scan was evaluated 3 months after reconstruction.

2.
Asian Cardiovasc Thorac Ann ; 27(2): 75-79, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30580530

ABSTRACT

BACKGROUND: Cardioplegia is an integral part of myocardial protection. The superiority of blood cardioplegia in adult patients has been reported. However, this is yet to be studied in cyanotic pediatric patients. METHODS: A randomized open-label trial was conducted in 70 patients with tetralogy of Fallot. They were divided into two groups: 35 patients had crystalloid cardioplegia (controls), and 35 had blood cardioplegia. Lactate and coronary oxygen extraction in arterial blood and the coronary sinus were measured immediately after cessation of cardiopulmonary bypass, 15 and 30 min later. Postoperative mortality, major adverse cardiac events, mechanical ventilation time, inotrope administration, arrhythmias, right ventricular function, intensive care unit and hospital length of stay were observed. RESULTS: There were no significant differences in clinical outcomes or lactate levels. There was a significant difference in coronary oxygen extraction immediately and 15 min after cessation of cardiopulmonary bypass ( p = 0.038, p = 0.015). CONCLUSION: Blood cardioplegia gave a better postoperative oxygen extraction value but there were no differences in myocardial damage or clinical outcome between the two groups.


Subject(s)
Cardiac Surgical Procedures , Cardioplegic Solutions/therapeutic use , Cardiopulmonary Bypass , Heart Arrest, Induced/methods , Potassium Compounds/therapeutic use , Tetralogy of Fallot/surgery , Adolescent , Adult , Biomarkers/blood , Cardiac Surgical Procedures/adverse effects , Cardioplegic Solutions/adverse effects , Cardiopulmonary Bypass/adverse effects , Child , Child, Preschool , Cyanosis/blood , Cyanosis/etiology , Female , Heart Arrest, Induced/adverse effects , Humans , Indonesia , Infant , Infant, Newborn , Lactic Acid/blood , Male , Oxygen/blood , Postoperative Complications/etiology , Potassium Compounds/adverse effects , Risk Factors , Tetralogy of Fallot/blood , Tetralogy of Fallot/complications , Tetralogy of Fallot/diagnostic imaging , Time Factors , Treatment Outcome , Young Adult
3.
Asian Cardiovasc Thorac Ann ; 26(3): 196-202, 2018 Mar.
Article in English | MEDLINE | ID: mdl-29448828

ABSTRACT

Introduction Myocardial protection is vital to ensure successful open heart surgery. Cardioplegic solution is one method to achieve good myocardial protection. Inevitably, ischemia-reperfusion injury occurs with aortic crossclamping. Histidine-tryptophan-ketoglutarate solution is a frequently used cardioplegia for complex congenital heart surgery. We postulated that addition of terminal warm blood cardioplegia before removal of the aortic crossclamp might improve myocardial protection. Method A randomized controlled trial was conducted on 109 cyanotic patients aged, 1 to 5 years who underwent complex biventricular repair. They were divided into a control group of 55 patients who had histidine-tryptophan-ketoglutarate only and a treatment group of 54 who had histidine-tryptophan-ketoglutarate with terminal warm blood cardioplegia. Endpoints were clinical parameters, troponin I levels, and caspase-3 as an apoptosis marker. Results The incidence of low cardiac output syndrome was 34%, with no significant difference between groups (35.2% vs. 33.3%, p = 0.84). The incidence of arrhythmias in our treatment group was lower compared to the control group (36% vs. 12%, p = 0.005). Troponin I and caspase-3 results did not show any significant differences between groups. For cases with Aristotle score ≥ 10, weak expression of caspase-3 in the treatment group post-cardiopulmonary bypass was lower compared to the control group. Conclusion For complex congenital cardiac surgery, the addition of terminal warm blood cardioplegia does not significantly improve postoperative clinical or metabolic markers.


Subject(s)
Cardioplegic Solutions/administration & dosage , Heart Arrest, Induced/methods , Heart Defects, Congenital/surgery , Temperature , Apoptosis , Arrhythmias, Cardiac/etiology , Biomarkers/blood , Cardiac Output, Low/etiology , Cardioplegic Solutions/adverse effects , Caspase 3/analysis , Child, Preschool , Female , Glucose/administration & dosage , Glucose/adverse effects , Heart Arrest, Induced/adverse effects , Heart Defects, Congenital/diagnostic imaging , Heart Defects, Congenital/physiopathology , Humans , Indonesia , Infant , Male , Mannitol/administration & dosage , Mannitol/adverse effects , Myocardium/chemistry , Myocardium/pathology , Potassium Chloride/administration & dosage , Potassium Chloride/adverse effects , Procaine/administration & dosage , Procaine/adverse effects , Time Factors , Treatment Outcome , Troponin I/blood
4.
SAGE Open Med Case Rep ; 5: 2050313X17744072, 2017.
Article in English | MEDLINE | ID: mdl-29242743

ABSTRACT

Isolated saccular compared to fusiform aneurysm is considered to be a rare entity with challenges of its own. A 62-year-old female was diagnosed with a case of saccular aneurysm and penetrating atherosclerotic ulcer of the aortic arch. Additionally, she also had one vessel coronary artery disease and type B abdominal aortic dissection. She was then managed with open aortic arch repair and coronary artery bypass grafting. If required, elective endovascular repair will be done for the abdominal aorta on a later date.

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