ABSTRACT
Results of investigation of collagen metabolism in Dupuitren's contracture (DC) were summarized. The patients were operated for calculous cholecystitis and DC stages II - III. The changes revealed witnessed about more expressed degradation of collagen and affection of the elastin components of connective tissue. On background of the pathological process progress in palmar aponeurosis in patients, suffering DC, a content of oxyproline have enhanced trustworthy in urine and reduced in tissue of a changed palmar aponeurosis.
Subject(s)
Cholecystitis/metabolism , Collagen/metabolism , Dupuytren Contracture/metabolism , Fascia/metabolism , Hydroxyproline/urine , Liver Cirrhosis/metabolism , Aged , Amino Acids/blood , Cholecystitis/complications , Cholecystitis/surgery , Connective Tissue/metabolism , Dupuytren Contracture/complications , Dupuytren Contracture/surgery , Elastin/metabolism , Humans , Liver Cirrhosis/complications , Male , Middle Aged , Severity of Illness IndexABSTRACT
The methods of multivariate analysis of lethality in combined trauma of the abdomen with the use of standardized measurement systems (STS) severity of the injury, including anatomical and functional assessment scales for prognostic survival probability victims in representative groups (by gender and age, mechanism and type of injury, clinical and nosological characteristics of damage).
Subject(s)
Abdominal Injuries/mortality , Multiple Trauma/mortality , Trauma Severity Indices , Wounds, Penetrating/mortality , Humans , Multivariate AnalysisABSTRACT
The results of morphological investigation of hepatic tissues in 98 patients, suffering contracture of Dupuytren, chronic hepatitis and hepatic fibrosis stages I, II i III, were adduced. The patients were operated on for calculous cholecystitis. The attempt to organize the groups with certain morphological changes, depending on the hepatic pathological process persistence (up to 5 yrs, from 5 to 10 yrs, over 10 yrs) have appeared nonfair. The changes revealed are too different and characteristic not only for the examined patients.
Subject(s)
Dupuytren Contracture/pathology , Hepatitis, Chronic/pathology , Liver/pathology , Aged , Cholecystitis/complications , Cholecystitis/pathology , Cholecystitis/surgery , Dupuytren Contracture/complications , Gallbladder/pathology , Gallbladder/surgery , Hepatitis, Chronic/complications , Hepatocytes/pathology , Histocytochemistry , Humans , Liver Cirrhosis/complications , Liver Cirrhosis/pathology , Male , Middle Aged , Severity of Illness IndexABSTRACT
Dupuytren's contracture--a pathology that should not be seen as an isolated lesion tendon-aponeurotic structures of the palmar surface of the hand, but as a disease that requires careful research and a comprehensive, differentiated approach to treatment. The aim of the study was to investigate the functional activity of the phagocytic system of Dupuytren's contracture patients with chronic hepatitis and liver fibrosis in liquidators of the CHNPP accident consequences. The resulting study 188 patients aged 45-65 years showed the correlation of the data of the functional activity of phagocytic system with degree of liver fibrosis, thus objectively assess the patient's condition and make the appropriate correction in the diagnostic criteria as well as in medical and rehabilitative programs.
Subject(s)
Chernobyl Nuclear Accident , Dupuytren Contracture/immunology , Environmental Exposure , Hepatitis, Chronic/immunology , Liver Cirrhosis/immunology , Phagocytosis/immunology , Aged , Dupuytren Contracture/complications , Dupuytren Contracture/pathology , Dupuytren Contracture/physiopathology , Hand/pathology , Hand/physiopathology , Hepatitis, Chronic/complications , Hepatitis, Chronic/pathology , Hepatitis, Chronic/physiopathology , Humans , Liver Cirrhosis/complications , Liver Cirrhosis/pathology , Liver Cirrhosis/physiopathology , Male , Middle Aged , Neutrophils/immunology , Neutrophils/pathology , Severity of Illness IndexABSTRACT
The results of experimental investigation, conducted on white Wistar rats, are adduced. The influence of intraabdominal pressure change on pancreatic parenchyma were studied in the animals. The data obtained witness the unfavourable influence of the raised intraabdominal pressure on pancreatic gland, manifesting by an acute pancreatitis occurrence.
