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1.
Int J Gynaecol Obstet ; 160 Suppl 1: 22-34, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36635079

ABSTRACT

Hypertensive disorders of pregnancy (HDP) are the most common causes of maternal and perinatal morbidity and mortality. They are responsible for 16% of maternal deaths in high-income countries and approximately 25% in low- and middle-income countries. The impact of HDP can be lifelong as they are a recognized risk factor for future cardiovascular disease. During pregnancy, the cardiovascular system undergoes significant adaptive changes that ensure adequate uteroplacental blood flow and exchange of oxygen and nutrients to nurture and accommodate the developing fetus. Failure to achieve normal cardiovascular adaptation is associated with the development of HDP. Hemodynamic alterations in women with a history of HDP can persist for years and predispose to long-term cardiovascular morbidity and mortality. Therefore, pregnancy and the postpartum period are an opportunity to identify women with underlying, often unrecognized, cardiovascular risk factors. It is important to develop strategies with lifestyle and therapeutic interventions to reduce the risk of future cardiovascular disease in those who have a history of HDP.


Subject(s)
Cardiovascular Diseases , Cardiovascular System , Hypertension, Pregnancy-Induced , Pre-Eclampsia , Pregnancy , Female , Humans , Hypertension, Pregnancy-Induced/epidemiology , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases/etiology , Risk Factors
2.
Int J Gynaecol Obstet ; 160 Suppl 1: 50-55, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36635080

ABSTRACT

Obesity has been linked to infertility through several mechanisms, including at a molecular level. Those living with obesity face additional barriers to accessing fertility treatments and achieving a successful pregnancy, which can contribute to their economic and psychosocial stressors. There is scope to further improve care for people living with obesity and infertility with empathy, via a multidisciplinary approach.


Subject(s)
Fertility , Infertility , Female , Humans , Pregnancy , Infertility/etiology , Infertility/therapy , Infertility/psychology , Obesity/complications , Obesity/therapy , Reproductive Techniques, Assisted
3.
Int J Gynaecol Obstet ; 160 Suppl 1: 35-49, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36635081

ABSTRACT

Obesity is a chronic, progressive, relapsing, and treatable multifactorial, neurobehavioral disease. According to the World Health Organization, obesity affects 15% of women and has long-term effects on women's health. The focus of care in patients with obesity should be on optimizing health outcomes rather than on weight loss. Appropriate and common language, considering cultural sensitivity and trauma-informed care, is needed to discuss obesity. Pregnancy is a time of significant physiological change. Pre-, ante-, and postpartum clinical encounters provide opportunities for health optimization for parents with obesity in terms of, but not limited to, fertility and breastfeeding. Pre-existing conditions may also be identified and managed. Beyond pregnancy, women with obesity are at an increased risk for gastrointestinal and liver diseases, impaired kidney function, obstructive sleep apnea, and venous thromboembolism. Gynecological and reproductive health of women living with obesity cannot be dismissed, with accommodations needed for preventive health screenings and consideration of increased risk for gynecologic malignancies. Mental wellness, specifically depression, should be screened and managed appropriately. Obesity is a complex condition and is increasing in prevalence with failure of public health interventions to achieve significant decrease. Future research efforts should focus on interprofessional care and discovering effective interventions for health optimization.


Subject(s)
Neoplasm Recurrence, Local , Obesity , Pregnancy , Female , Humans , Obesity/complications , Obesity/therapy , Obesity/epidemiology , Women's Health , Postpartum Period , Mental Health
4.
Int J Gynaecol Obstet ; 160 Suppl 1: 10-21, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36635083

ABSTRACT

The period before and during pregnancy is increasingly recognized as an important stage for addressing malnutrition. This can help to reduce the risk of noncommunicable diseases in mothers and passage of risk to their infants. The FIGO Nutrition Checklist is a tool designed to address these issues. The checklist contains questions on specific dietary requirements, body mass index, diet quality, and micronutrients. Through answering these questions, awareness is generated, potential risks are identified, and information is collected that can inform health-promoting conversations between women and their healthcare professionals. The tool can be used across a range of health settings, regions, and life stages. The aim of this review is to summarize nutritional recommendations related to the FIGO Nutrition Checklist to support healthcare providers using it in practice. Included is a selection of global dietary recommendations for each of the components of the checklist and practical insights from countries that have used it. Implementation of the FIGO Nutrition Checklist will help identify potential nutritional deficiencies in women so that they can be addressed by healthcare providers. This has potential longstanding benefits for mothers and their children, across generations.


Subject(s)
Checklist , Diet , Pregnancy , Infant , Child , Humans , Female , Counseling , Health Personnel , Delivery of Health Care
5.
Int J Gynaecol Obstet ; 160 Suppl 1: 56-67, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36635082

ABSTRACT

Gestational diabetes (GDM) impacts approximately 17 million pregnancies worldwide. Women with a history of GDM have an 8-10-fold higher risk of developing type 2 diabetes and a 2-fold higher risk of developing cardiovascular disease (CVD) compared with women without prior GDM. Although it is possible to prevent and/or delay progression of GDM to type 2 diabetes, this is not widely undertaken. Considering the increasing global rates of type 2 diabetes and CVD in women, it is essential to utilize pregnancy as an opportunity to identify women at risk and initiate preventive intervention. This article reviews existing clinical guidelines for postpartum identification and management of women with previous GDM and identifies key recommendations for the prevention and/or delayed progression to type 2 diabetes for global clinical practice.


Subject(s)
Cardiovascular Diseases , Diabetes Mellitus, Type 2 , Diabetes, Gestational , Pregnancy , Female , Humans , Diabetes Mellitus, Type 2/prevention & control , Diabetes, Gestational/diagnosis , Diabetes, Gestational/prevention & control , Postpartum Period , Cardiovascular Diseases/etiology , Cardiovascular Diseases/prevention & control , Risk Factors
7.
J Womens Health (Larchmt) ; 30(3): 305-313, 2021 03.
Article in English | MEDLINE | ID: mdl-32986503

ABSTRACT

Background: Preeclampsia predicts future cardiovascular disease (CVD) yet few programs exist for post-preeclampsia care. Methods: The Health after Preeclampsia Patient and Provider Engagement Network workshop was convened at the Radcliffe Institute for Advanced Study in June 2018. The workshop sought to identify: 1) patient perspectives on barriers and facilitators to CVD risk reduction; 2) clinical programs specialized in post-preeclampsia care; 3) recommendations by national organizations for risk reduction; and 4) next steps. Stakeholders included the Preeclampsia Foundation, patients, clinicians who had initiated CVD risk reduction programs for women with prior preeclampsia, researchers, and national task force members. Results: Participants agreed there is insufficient awareness and action to prevent CVD after preeclampsia. Patients suggested a clinician checklist to ensure communication of CVD risks, enhanced training for clinicians on the link between preeclampsia and CVD, and a post-delivery appointment with a clinician knowledgeable about this link. Clinical programs primarily served patients in the first postpartum year, bridging obstetrical and primary care. They recommended CVD risk modification with periodic blood pressure, weight, lipid and diabetes screening. Barriers included the paucity of programs designed for this population and gaps in insurance coverage after delivery. The American Heart Association, the American College of Obstetricians and Gynecologists, and the Preeclampsia Foundation have developed guidelines and materials for patients and providers to guide management of women with prior preeclampsia. Conclusions: Integrated efforts of patients, caregivers, researchers, and national organizations are needed to improve CVD prevention after preeclampsia. This meeting's recommendations can serve as a resource and catalyst for this effort.


Subject(s)
Cardiovascular Diseases , Cardiovascular System , Obstetrics , Pre-Eclampsia , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases/prevention & control , Female , Humans , Pregnancy , Risk Factors , Risk Reduction Behavior
10.
J Am Coll Cardiol ; 71(16): 1797-1813, 2018 04 24.
Article in English | MEDLINE | ID: mdl-29673470

ABSTRACT

Hypertension accounts for 1 in 5 deaths among American women, posing a greater burden for women than men, and is among their most important risk factors for death and development of cardiovascular and other diseases. Hypertension affects women in all phases of life, with specific characteristics relating to risk factors and management for primary prevention of hypertension in teenage and young adult women; hypertension in pregnancy; hypertension during use of oral contraceptives and assisted reproductive technologies, lactation, menopause, or hormone replacement; hypertension in elderly women; and issues of race and ethnicity. All are detailed in this review, as is information relative to women in clinical trials of hypertension and medication issues. The overarching message is that effective treatment and control of hypertension improves cardiovascular outcomes. But many knowledge gaps persist, including the contribution of hypertensive disorders of pregnancy to cardiovascular disease risk, the role of hormone replacement, blood pressure targets for elderly women, and so on.


Subject(s)
Hypertension/therapy , Life Cycle Stages , Adolescent , Adult , Aged , Clinical Trials as Topic , Female , Humans , Hypertension/ethnology , Hypertension/etiology , Menopause , Middle Aged , Pregnancy , Primary Prevention , Racial Groups , Young Adult
12.
Adv Chronic Kidney Dis ; 20(3): 287-96, 2013 May.
Article in English | MEDLINE | ID: mdl-23928395

ABSTRACT

Preeclampsia is a pregnancy-specific syndrome that usually develops after 20 weeks gestation. The exact pathogenic mechanisms remain uncertain and are likely multifactorial. Preeclampsia is a heterogeneous condition with potentially maternal and fetal consequences. As part of the spectrum of hypertensive disorders of pregnancy, preeclampsia may progress rapidly and is a leading cause of maternal and perinatal morbidity and mortality worldwide. In the United States, the incidence of preeclampsia has increased. Clinical manifestations are highly variable and may occur antepartum, intrapartum, or postpartum. Hypertension and proteinuria are the traditional hallmarks for the diagnosis of preeclampsia. These signs may occur with or without multisystem dysfunction and fetal involvement. Risk factors have been identified for the development of preeclampsia; however, ideal methods for prevention, screening, and treatment remain elusive. Preeclampsia resolves after delivery of the fetus, but patients may still have hypertension postpartum. Women and fetuses affected by preeclampsia are at higher risk of developing long-term health issues. There appear to be risk factors common to hypertensive disorders of pregnancy and cardiovascular disease seen later in adulthood. Physicians providing healthcare to women are urged to recognize potential risk factors that arise from patient obstetric histories so that optimal long-term health surveillance is provided.


Subject(s)
Pre-Eclampsia/classification , Delivery, Obstetric , Female , Humans , Hypertension/classification , Hypertension/physiopathology , Hypertension/therapy , Hypertension, Pregnancy-Induced/classification , Hypertension, Pregnancy-Induced/physiopathology , Hypertension, Pregnancy-Induced/therapy , Kidney/physiopathology , Liver/physiopathology , Pre-Eclampsia/physiopathology , Pre-Eclampsia/therapy , Pregnancy , Pregnancy Complications, Cardiovascular/classification , Pregnancy Complications, Cardiovascular/physiopathology , Pregnancy Complications, Cardiovascular/therapy , Pregnancy Complications, Hematologic/physiopathology , Pregnancy Complications, Hematologic/therapy , Risk Factors , Thrombocytopenia/physiopathology , Thrombocytopenia/therapy
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