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Rev Clin Esp ; 186(1): 19-22, 1990 Jan.
Article in Spanish | MEDLINE | ID: mdl-2108478

ABSTRACT

This study reveals the efficiency of phenobarbital, diphenilhidantoine, carbamazepine, valproic acid and teophyline serum levels for their correct adjustment within the concentration gap considered optimal to produce the desired pharmacological effect. A total population of 882 patients treated with the drugs previously named is studied and an important improvement in dose adjustment is observed during these years as a consequence of drug's serum level knowledge.


Subject(s)
Carbamazepine/therapeutic use , Phenobarbital/therapeutic use , Phenytoin , Theophylline/therapeutic use , Valproic Acid/therapeutic use , Carbamazepine/blood , Dose-Response Relationship, Drug , Drug Administration Schedule , Drug Utilization , Humans , Phenobarbital/blood , Phenytoin/blood , Phenytoin/therapeutic use , Product Surveillance, Postmarketing , Spain , Theophylline/blood , Valproic Acid/blood
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