ABSTRACT
Ischemic cardiomyopathy (ICMP) constitutes the organspecific systemic form of autoimmune pathology. Now existing hypotheses of the ICMP pathogenesis trust the multistaged course of the disease with concurrent changes in the cellular and humoral chains of immunity. Among the immune disorders there are interrelated chains, influencing the disease course severity. Dysfunction of T- and B-lymphocytes, natural cell-killers (EKK-CD16+), R-IL2 (CD25+), apoptosis (CD95+), pro- and antiinflammatory cytokines causes changes in myocardium contractility, occurrence of congestion events, chronic cardiac insufficiency.
Subject(s)
Antibody Formation , Cardiomyopathies/immunology , Immunity, Cellular , Myocardial Ischemia/immunology , B-Lymphocytes/immunology , Cardiomyopathies/etiology , Cytokines/immunology , Female , Humans , Male , Middle Aged , Myocardial Ischemia/complications , T-Lymphocytes/immunologyABSTRACT
An analysis of results of treatment of 228 patients with wounds of the lumbar region has shown that in 66.2% of cases they were not penetrating, in 33.8% they were penetrating. In 42 patients there were injuries of internal organs and of the vessels of the abdominal cavity and retroperitoneal space. The casualties must be examined under conditions of the emergency operating room and which in addition to thorough revision of the wound must include subsidiary methods of examination: USI, survey radiography of the thoracic and abdominal cavities and diagnostic survey laparoscopy, if necessary.
Subject(s)
Lumbar Vertebrae/injuries , Lumbar Vertebrae/surgery , Wounds and Injuries/diagnosis , Wounds, Gunshot/surgery , Adolescent , Adult , Aged , Humans , Male , Middle Aged , Severity of Illness IndexABSTRACT
The data concerning the role of the immune and inflammatory reactions activation in formation of dilatational and hypertrophic cardiomyopathy were presented. The dependence of the humoral-inflammatory disbalance progressing on the processes of the apoptosis and inflammatory cytokins level regulation, determining the immune answer disorder degree in relation with cardiomyopathy form, was established.
Subject(s)
Cardiomyopathy, Dilated/immunology , Cardiomyopathy, Hypertrophic/immunology , Adaptation, Physiological/immunology , Cardiomyopathy, Dilated/diagnosis , Cardiomyopathy, Hypertrophic/diagnosis , Cytokines/immunology , Diagnosis, Differential , Humans , Lymphocyte Count , T-Lymphocyte Subsets/cytology , T-Lymphocyte Subsets/immunologyABSTRACT
A retrospective analysis of treatment of 436 patients with acute bleedings from tumors of the gastrointestinal tract was made. Elderly and senile patients made up 72% of the hospitalized patients. The emergency complex diagnostics in 75% of the patients under conditions of a multi-profile hospital allowed the source of bleeding to be detected during the first day, the strategy of treatment being also determined. Radical operations could be fulfilled both in emergency and planned order on most patients. Lethality of patients with tumors of the stomach and colon after radical operations was 10%, after palliative operations 29.5% and 27.9% respectively. Acute bleedings from tumors of the gastrointestinal tract is not the absolute sign of the patient being inoperable.
Subject(s)
Gastrointestinal Hemorrhage/etiology , Gastrointestinal Neoplasms/complications , Acute Disease , Adult , Aged , Aged, 80 and over , Digestive System Surgical Procedures/methods , Female , Follow-Up Studies , Gastrointestinal Hemorrhage/surgery , Hemostasis, Surgical/methods , Humans , Male , Middle Aged , Prognosis , Retrospective StudiesABSTRACT
The authors present results of surgical treatment of 98 patients with gluteal wounds. In 93.9% of cases the wounds were not penetrating and in 6.1% there were penetrating wounds. All the patients admitted to hospitals in state of shock as well as suspected to the penetrating character of the wound underwent general laparoscopy. In 2 patients with penetrating wounds of the abdominal cavity and in 7 patients with non-penetrating wounds ligation of the internal iliac artery was necessary because of huge bleeding. Two patients (2%) with penetrating wounds of the abdominal cavity died.
Subject(s)
Buttocks/injuries , Wounds, Gunshot/diagnosis , Wounds, Gunshot/therapy , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Shock, Traumatic/epidemiology , Wounds, Gunshot/epidemiologyABSTRACT
Investigations of the lymphatic bed of lower extremities by the method of rentgen-contrast lymphography were performed in 64 patients with trophic ulcers of lower extremities and postthrombotic disease. The data obtained by lymphography allowed formation of a group of patients perspective for treatment by lymphotropic antibacterial therapy. The lymphotropic therapy using Gentamycin and Cefazolin resulted in a more rapid arresting of local inflammatory alterations and development of reparative processes in the trophic ulcer area and in normalization of the main clinico-laboratory parameters.
Subject(s)
Leg Ulcer/drug therapy , Leg/physiopathology , Lymphatic System/physiopathology , Varicose Ulcer/drug therapy , Adult , Aged , Cefazolin/therapeutic use , Gentamicins/therapeutic use , Humans , Male , Middle AgedABSTRACT
Gas chromatographic measurement of fatty acid spectrum and free cholesterol level in exhaled air condensate of children suffering from asthma has revealed a deficiency of polyunsaturated fatty acids and lipids at the expense of linoleic and arachidonic acids.