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1.
Przegl Lek ; 59(1): 49-54, 2002.
Article in Polish | MEDLINE | ID: mdl-12108048

ABSTRACT

Cardinal pathological mechanisms responsible for initiation and development of the Raynaud's phenomenon have been presented according to the current data from literature. The role of endothelin-1, cytokins and growth factor in pathophysiology of this phenomenon have been highlighted. According to own observations randomised results of investigation in these patients have shown that basic disease stimulate the development of the vasomotoric disturbances: idiopathic Raynaud's phenomenon and Raynaud's phenomenon which accompany connective tissue disease.


Subject(s)
Raynaud Disease/physiopathology , Cytokines/metabolism , Endothelins/metabolism , Humans , Raynaud Disease/etiology , Raynaud Disease/metabolism , Tumor Necrosis Factor-alpha/metabolism
2.
Pol Merkur Lekarski ; 12(70): 322-7, 2002 Apr.
Article in Polish | MEDLINE | ID: mdl-12089899

ABSTRACT

Based on literary data we carried out the analysis of the influence vascular endothelium on maintaining the haematological and circulatory balance in the organism. Particular attention was paid on its active metabolic and secretory role in this process.


Subject(s)
Endothelium, Vascular/physiology , Blood Circulation , Endothelium, Vascular/metabolism , Endothelium, Vascular/physiopathology , Humans , Nitric Oxide/metabolism , Peptides/metabolism , Vasculitis/metabolism , Vasculitis/physiopathology
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