The Impact of Pruritus on the Quality of Life and Sleep Disturbances in Patients Suffering from Different Clinical Variants of Psoriasis.

BACKGROUND: Quality of life (QoL) and sleep, which are essential for well-being in the mental, physical, and socioeconomic domains, are impaired in psoriatic patients. However, the exact role of the clinical subtype of psoriasis in this aspect remains poorly studied. OBJECTIVES: The aim of this study was to investigate differences in QoL impairment and sleeping problems in patients suffering from various clinical subtypes of psoriasis and to evaluate the effects of pruritus on QoL. METHODS: This cross-sectional, multicenter study included 295 eligible subjects with diagnosed psoriasis. Each patient was examined with the use of the same questionnaire. Measures included predominant subtype of psoriasis, disease severity, pruritus scores, patients' health-related QoL and the incidence of sleep disturbance. RESULTS: The QoL of most patients was decreased irrespectively of clinical psoriasis subtype, however, the most impaired QoL was in patients with erythrodermic psoriasis. The majority of patients reported sleep disturbances caused by pruritus, albeit there was no relevant differences between analyzed subgroups in this aspect of patients' well-being. Pruritus was an important factor determining QoL and sleeping problems in the studied population. CONCLUSIONS: Identifying the most disturbing area of life and recognizing the most bothersome subjective symptoms of psoriasis are pivotal to focusing on the most relevant treatment goal and achieving therapeutic success.

Comparison of the Physical Fitness Profile of Muay Thai and Brazilian Jiu-Jitsu Athletes with Reference to Training Experience.

BACKGROUND: In combat sports, successful competition and training require comprehensive motor fitness. The aim of this study was to diagnose the level of physical fitness and to determine the level of differences between athletes of combat sports characterized by stand-up fighting, such as Muay Thai; and ground fighting, such as Brazilian jiu-jitsu. METHODS: The study examined and compared 30 participants divided into two equal groups: Muay Thai athletes (n = 15; age: 24.24 ± 3.24; body height: 174.91 ± 5.19; body weight: 77.56 ± 7.3), and Brazilian jiu-jitsu (BJJ) (n = 15; age: 22.82 ± 1.81; body height: 175.72 ± 7.03; body weight: 77.11 ± 8.12). Basic characteristics of the somatic build were measured. Selected manifestations of the motor potential of motor skills were also evaluated using selected tests from the EUROFIT test battery, the International Test of Physical Fitness, and computer tests of coordination skills. Relative strength and maximal anaerobic work (MAW) indices were calculated. The strength of the relationship between the effect of motor fitness and training experience was also assessed. RESULTS: The athletes of both groups (Muay Thai and BJJ) presented similar levels of basic characteristics of the somatic build. Motor fitness in the tested groups showed significant differences between the athletes of these sports in static strength (p = 0.010), relative strength (p = 0.006), arm muscle strength in pull-ups (p = 0.035), and functional strength in bent arm hanging (p = 0.023). Higher levels of these components of motor fitness were found for the athletes in the BJJ athletes. In the Muay Thai group, significant very high strength of association was found between training experience and five strength tests. Furthermore, a significantly high strength of association was found in two tests. In the BJJ group, significant relationships with very high correlation were found between the variables in five strength tests. CONCLUSIONS: Brazilian jiu-jitsu athletes performed better in strength tests (static strength, relative strength, shoulder girdle strength, functional strength). High correlations between the training load and the level of physical fitness were found in flexibility and strength tests in BJJ athletes and most strength tests in Muay Thai athletes.

The effect of expertise on postural control in elite sport ju-jitsu athletes.

BACKGROUND: Due to the high postural control demands of sport ju-jitsu, it is likely that long-term sport ju-jitsu training may induce sport-specific adaptations in postural control, especially in positions directly related to combat. The aim of the study was to assess the differences in postural control between elite sport ju-jitsu athletes and untrained controls in non-ecological and ecological conditions and to investigate the relative contribution of spinal and supraspinal mechanisms to postural control in expert athletes. METHODS: The study was conducted on eleven male elite ju-jitsu athletes and ten non-athletes. The data was collected with the use of a force plate under two conditions: quiet standing and ju-jitsu combat stance. Apart from the standard analysis of the spatial-temporal parameters of center of foot pressure, non-linear measures were used, namely rambling-trembling and sample entropy. The non-parametric Mann-Whitney U test was used to compare both groups. RESULTS: The main findings of the study showed that in quiet standing, elite ju-jitsu athletes and non-athletes had comparable postural control in both the anterior-posterior and mediolateral planes. In contrast, in the combat stance, elite athletes had lower values of postural sway and rambling component (range and rms) and higher values of sample entropy in comparison to the non-athletes (p < 0.05). No differences were found in the trembling component of sway between groups in the combat stance (p < 0.05). CONCLUSIONS: Smaller postural sway and its rambling component in sport ju-jitsu athletes may indicate the more precise control of center of foot pressure and improved ability in estimating its position. The sample entropy results confirmed that the displacement of center of foot pressure for sport ju-jitsu athletes was more irregular, which demonstrates greater automatization in postural control. The results also confirm the importance of ecological validity in investigating postural adaptations associated with sports expertise.

COVID-19 and Postural Control-A Stabilographic Study Using Rambling-Trembling Decomposition Method.

Background and Objectives: Some respiratory viruses demonstrate neurotropic capacities. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently taken over the globe, causing coronavirus disease 2019 (COVID-19). The aim of the study was to evaluate the impact of COVID-19 on postural control in subjects who have recently recovered from the infection. Materials and Methods: Thirty-three convalescents who underwent COVID-19 within the preceding 2-4 weeks, and 35 healthy controls were enrolled. The ground reaction forces were registered with the use of a force platform during quiet standing. The analysis of the resultant center of foot pressure (COP) decomposed into rambling (RAMB) and trembling (TREMB) and sample entropy was conducted. Results: Range of TREMB was significantly increased in subjects who experienced anosmia/hyposmia during COVID-19 when the measurement was performed with closed eyes (p = 0.03). In addition, subjects who reported dyspnea during COVID-19 demonstrated significant increase of length and velocity of COP (p < 0.001), RAMB (p < 0.001), and TREMB (p < 0.001), indicating substantial changes in postural control. Conclusions: Subjects who had experienced olfactory dysfunction or respiratory distress during COVID-19 demonstrate symptoms of balance deficits after COVID-19 recovery, and the analysis using rambling-trembling decomposition method might point at less efficient peripheral control. Monitoring for neurological sequelae of COVID-19 should be considered.

A Compound Hop Index for Assessing Soccer Players' Performance.

Athletes regularly have to pass a series of tests, among which one of the most frequently used functional performance measures are single-leg hop tests. As the collected individual results of tests constitute a large amount of data, strategies to decrease the amount of data without reducing the number of performed tests are being searched for. Therefore, the study aimed to present an effective method to reduce the hop-test battery data to a single score, namely, the Compound Hop Index (CHI) in the example of a soccer team. A male, first-league soccer team performed a battery of commonly used single-leg hop tests, including single hop and triple hop for distance tests and the six-meter timed hop test. Gathered data, including Limb Symmetry Indexes of the three tests, normalized to body height for the single- and triple-hop-tests distance separately for right and left legs, and the time of the six-meter timed hop test separately for right and left legs were standardized to z-scores. Consecutively, the z-scores were averaged and formed CHI. The developed CHI represents a novel score derived from the average of z-scores that significantly reduces, clarifies, and organizes the hop performance-measures data.

Association Analysis of Polymorphic Variants of the BDNF Gene in Athletes.

As BDNF is one of the group of neurotrophins highly influencing the processes happening in the brain, such as the processes of learning and personality creation, we decided to look closer at its genetic variations in association with the personality of a group of athletes and their controls. The study group consisted of 305 volunteers: martial arts athletes (n = 153; mean age = 24.06) and healthy non-athletes as controls (n = 152; mean age = 22.23). Thirty-eight percent of the martial arts group achieved the championship level. Both the martial arts and control subjects were examined using the NEO Five-Factor Personality Inventory (NEO-FFI) and the State-Trait Anxiety Inventory (STAI) scales. The results of the NEO-FFI and STAI inventories were given as sten scores. The conversion of the raw score to the sten scale was performed according to Polish norms for adults. Genomic DNA was extracted from blood leukocytes and then genotyped using a PCR method for the following polymorphisms: BDNF rs10767664 and BDNF rs2030323. We observed statistical significance for both polymorphisms when comparing martial arts athletes with the control group in relation to the conscientiousness and extraversion scales. However, since few extant articles consider this association, our results still require further analysis, probably by considering a larger group.

Reliability of Pelvic Floor Muscle Assessment with Transabdominal Ultrasound in Young Nulliparous Women.

The aim of this study was to assess the reliability of pelvic floor muscles evaluation via transabdominal ultrasonography in young nulliparous women and to present the methodology for quantitative assessment of the ultrasound image of the pelvic floor muscles visible as displacement of the posterior wall of the bladder, caused by action of the pelvic floor muscles. The study comprised 30 young, Caucasian, nulliparous women (age 22-27; 168.6 ± 5.1 cm; 57.1 ± 11.8 kg) without pelvic floor muscle dysfunctions. The intra-rater, test-retest and inter-rater reliability of pelvic floor muscles evaluation was performed using transabdominal ultrasound at rest and during voluntary contraction. The reliability was assessed at three points of the image (at the middle, on the right and left side). The reliability of the three-point measurement of the pelvic floor muscles transabdominal ultrasound is excellent in the case of intra-rater assessments, both at rest (ICC = 0.98-0.99) and during contraction (ICC = 0.97-0.98); moderate at rest (ICC = 0.54-0.62) and poor during contraction (ICC = 0.22-0.50) in the case of test-retest assessment; excellent at rest (ICC = 0.95-0.96), and good during contraction (ICC = 0.81-0.87) in the case of inter-rater assessment. Transabdominal ultrasound is a reliable method of pelvic floor muscle evaluation. The three-points of assessment used in our study allowed for broader and more comprehensive imaging of the pelvic floor muscle, e.g., for quantitative detection contractility imbalances between the left and right side Due to the fact that understanding mechanisms of pelvic floor muscle functioning is crucial in the therapy of pelvic floor dysfunctions, therefore, reliable, valid tests and instruments are important.

Molecular Aspects of Pruritus Pathogenesis in Psoriasis.

Psoriasis is a chronic, systemic inflammatory disease with a genetic background that involves almost 3% of the general population worldwide. Approximately, 70-90% of patients with psoriasis suffer from pruritus, an unpleasant sensation that provokes a desire to scratch. Despite the enormous progress in understanding the mechanisms that cause psoriasis, the pathogenesis of psoriasis-related pruritus still remains unclear. In order to improve patients' quality of life, development of more effective and safer antipruritic therapies is necessary. In turn to make it possible, better understanding of complexed and multifactorial pathogenesis of this symptom is needed. In this article we have systematized the current knowledge about pruritus origin in psoriasis.

Functional fitness normative values for elderly polish population.

BACKGROUND: It's really important to measure the actual functional physical fitness of elderly independent living persons from different environments to know the level and rate of decrease may inform about the threat of loss of functional independence, hence the need to monitor and assess the senior's motor realm and adapt to it the appropriate programs and treatments in the care for the elderly person. METHODS: The study involved 5367 people (mean age 69,63 ± 7,06), including 4164 women (mean age 69,55 ± 7,11) and 1203 men (mean age 69,91 ± 6,86) aged 60 to 93 years old. We have measured basic anthropometric features and physical fitness (by using Senior Fitness Test). RESULTS: The average values in individual SFT tests significantly decrease along with age. After age of 80 and 85 there were no sex differences in SFT. The largest deficits concern the dynamic balance and the decrease reaches 69% in men and 62% in women A significantly higher rate of decline in aerobic capacity concerns men (43%) than women (36.9%). A clearly lower rate of loss occurs in the muscular strength of the lower and upper body and does not exceed 30%. CONCLUSIONS: The results are of great clinical importance for the development of effective prevention and gerontological education programs in terms of promoting active lifestyle and successful ageing, at the same time limiting the economic consequences of treatment and hospitalisation.

The Effect of Training Experience on Postural Control in Competitive Wrestlers.

The aim of this study was to evaluate the effects of training experience in wrestling on postural control. Fourteen elite athletes with at least 8 years of wrestling training and competition experience participated in the study. The control group consisted of fifteen healthy adults who were not competitive athletes. The center of pressure (COP) trajectories were recorded with the use of an AMTI force plate at a sampling frequency of 50 Hz. The rambling-trembling decomposition method was used to analyze the COP trajectory data. The main finding was a significant effect of training experience on postural control in only the sagittal plane. Interestingly, significant differences in velocity were observed for the trembling component of the COP. All described variables were significantly higher in wrestlers. We hypothesized that balance training may lead to task-specific neural adaptations at the spinal and supraspinal levels. It was concluded that further research of high methodological quality is needed to determine the effect of training experience on balance control in elite athletes. Additionally, this effect should be observed in youth athletes, as it may be treated as a selection criteria in the training process.

Effects of Reduced Effort on Mechanical Output Obtained From Maximum Vertical Jumps.

The aim of this study was to evaluate the effect of reduced effort on maximum countermovement jumps. Groups of unskilled and skilled jumpers performed countermovement jumps without an arm swing at 100% and 50% effort. The results revealed markedly reduced jump height and work performed at 50% effort, although the maximum force and power output remained virtually unchanged. The observed differences were consistent across individuals with different jumping skills. A possible cause of differences in changes across the tested variables was a reduced countermovement depth associated with the 50% effort jumps. It is known to cause an increase in maximum force and power outputs, but not in jump height. Therefore, the jump height and work performed may be more closely related to our sense of effort when jumping, rather than our maximum force and power output. From a practical perspective, the present findings reiterate the importance of maximizing effort for making valid assessments of muscle mechanical capacities, as tested by maximal vertical jumps and, possibly, other maximum performance tasks.

The influence of different intensity treadmill efforts on the sense of rhythm of non-professional runners - pilot study.

PURPOSE: The purpose of this study was to determine how global effort affects the rhythm of multi-joint coordination in the global task. We wanted to examine how this specific kind of fatigue impacts sense of rhythm. METHODS: In this study, fourteen non-professsional runners performed two effort trials of different intensity, where speed was set individually according to the speed of running when par- ticipants reached lactate threshold. Before and after each effort trial they had to perform the rhythm test. RESULTS: Two-way analysis of variance ANOVA did not reveal significant differences among the variables of pre- and post-effort rhythm test. It is suggested that these results are supported by the application of different movement strategies to compensate for fatigue, and possible motor learning effect of simple timing performance. CONCLUSIONS: In our opinion the training workout routine should include cyclic technical exercises after fatigue. Not only to develop and improve energetics of movement, but also to learn and perfect different movement patterns and develop novel movement strategies.

The Effects of Cryotherapy on Knee Joint Position Sense and Force Production Sense in Healthy Individuals.

The proprioceptive information received from mechanoreceptors is potentially responsible for controlling the joint position and force differentiation. However, it is unknown whether cryotherapy influences this complex mechanism. Previously reported results are not universally conclusive and sometimes even contradictory. The main objective of this study was to investigate the impact of local cryotherapy on knee joint position sense (JPS) and force production sense (FPS). The study group consisted of 55 healthy participants (age: 21 ± 2 years, body height: 171.2 ± 9 cm, body mass: 63.3 ± 12 kg, BMI: 21.5 ± 2.6). Local cooling was achieved with the use of gel-packs cooled to -2 ± 2.5°C and applied simultaneously over the knee joint and the quadriceps femoris muscle for 20 minutes. JPS and FPS were evaluated using the Biodex System 4 Pro apparatus. Repeated measures analysis of variance (ANOVA) did not show any statistically significant changes of the JPS and FPS under application of cryotherapy for all analyzed variables: the JPS's absolute error (p = 0.976), its relative error (p = 0.295), and its variable error (p = 0.489); the FPS's absolute error (p = 0.688), its relative error (p = 0.193), and its variable error (p = 0.123). The results indicate that local cooling does not affect proprioceptive acuity of the healthy knee joint. They also suggest that local limited cooling before physical activity at low velocity did not present health or injury risk in this particular study group.

Evaluation of reliability and concurrent validity of two optoelectric systems used for recording maximum vertical jumping performance versus the gold standard.

PURPOSE: The objective of this study was to evaluate the reliability and validity of two alternative systems used for jumping performance measurement. METHODS: Two groups of subjects were tested. The first group consisted of 15 male adults (21.3 ± 1.7 years) and the second group consisted of 16 female volleyball players (17.2 ± 0.9 years). We used three different systems of data collection in the study. Two of the used systems are based on optoelectric components. The Optojump Next system is referred to as the optoelectric system, and BTS Smart-E is refered to as the video system. Concurrent validity of these systems was verified with the use of "gold standard" which is force platform. All systems were used to estimate the height of vertical jumps. RESULTS: Both optoelectric systems turned out to be highly reliable with the ICCs = 0.98 for Optojump and 0.9 for BTS Smart. Their concurrent validity with the force platform data was also very high r = 0.99 and r = 0.97, respectively. CONCLUSIONS: Comparison of these two systems shows distinct differences between them. Out of the two systems, Optojump system is more suitable for quick and reliable sports testing while when BTS-Smart is better for research and clinical testing.

Intra-Personal and Inter-Personal Kinetic Synergies During Jumping.

We explored synergies between two legs and two subjects during preparation for a long jump into a target. Synergies were expected during one-person jumping. No such synergies were expected between two persons jumping in parallel without additional contact, while synergies were expected to emerge with haptic contact and become stronger with strong mechanical contact. Subjects performed jumps either alone (each foot standing on a separate force platform) or in dyads (parallel to each other, each person standing on a separate force platform) without any contact, with haptic contact, and with strong coupling. Strong negative correlations between pairs of force variables (strong synergies) were seen in the vertical force in one-person jumps and weaker synergies in two-person jumps with the strong contact. For other force variables, only weak synergies were present in one-person jumps and no negative correlations between pairs of force variable for two-person jumps. Pairs of moment variables from the two force platforms at steady state showed positive correlations, which were strong in one-person jumps and weaker, but still significant, in two-person jumps with the haptic and strong contact. Anticipatory synergy adjustments prior to action initiation were observed in one-person trials only. We interpret the different results for the force and moment variables at steady state as reflections of postural sway.