ABSTRACT
El sarcoma de Kaposi es una neoplasia vascular de bajo grado, de la cual existen cuatro variantes fundamentales, una de las cuales se relaciona con el virus de la inmunodeficiencia humana. Sus manifestaciones más características son la presencia de lesiones mucocutáneas y la afectación de los ganglios linfáticos. El tracto gastrointestinal está implicado en el 40% de los casos, aunque la aparición de lesiones en el recto y en el canal anal es excepcional. Presentamos el caso de un varón de 39 años con virus de la inmunodeficiencia humana positivo, diagnosticado endoscópicamente de sarcoma de Kaposi con afectación colorrectal y del canal anal, y sin lesiones cutáneas asociadas que presentó una respuesta parcial al tratamiento antirretroviral combinado con quimioterapia sistémica y una remisión local al aplicar radioterapia sobre la lesión anal (AU)
Kaposi's sarcoma (KS) is a low-grade vascular tumor, with four main variants, one of which is fairly prevalent in HIV-infected patients. Mucocutaneus and lymph node involvement is characteristic. The gastrointestinal tract is involved in 40% of patients, but rectal and anal canal involvement is exceptional. We report the case of a 39-year-old HIV-infected man with an unusual presentation of KS with colorectal and anal canal involvement in the absence of cutaneous disease. The patient was treated with highly active antiretroviral therapy and systemic chemotherapy, with partial response. Local radiation therapy of the rectum produced local remission (AU)
Subject(s)
Humans , Male , Adult , Anus Neoplasms , Colorectal Neoplasms , Sarcoma, Kaposi , Neoplasms, Multiple Primary , Anus Neoplasms/diagnosis , Anus Neoplasms/drug therapy , Colorectal Neoplasms/diagnosis , Colorectal Neoplasms/drug therapy , Sarcoma, Kaposi/diagnosis , Sarcoma, Kaposi/drug therapy , Neoplasms, Multiple Primary/diagnosis , Neoplasms, Multiple Primary/drug therapyABSTRACT
Kaposi's sarcoma (KS) is a low-grade vascular tumor, with four main variants, one of which is fairly prevalent in HIV-infected patients. Mucocutaneus and lymph node involvement is characteristic. The gastrointestinal tract is involved in 40% of patients, but rectal and anal canal involvement is exceptional. We report the case of a 39-year-old HIV-infected man with an unusual presentation of KS with colorectal and anal canal involvement in the absence of cutaneous disease. The patient was treated with highly active antiretroviral therapy and systemic chemotherapy, with partial response. Local radiation therapy of the rectum produced local remission.