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1.
Parasitol Int ; 101: 102878, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38452972

ABSTRACT

OBJECTIVE: A case description of a rare occurrence of female genital schistosomiasis affecting the upper genital tract that presented with features mimicking an ovarian neoplasm. CASE REPORT: Female genital schistosomiasis is a neglected clinical manifestation of the water-born parasitic disease which occurs due to the presence of schistosome eggs in the genitalia of women. A 23-year-old nulliparous woman presented with progressive abdominal distension. An abdominopelvic CT scan revealed a multilobulated right adnexal mass with gross ascites. Diagnosis of schistosomiasis was made by histology of biopsied specimens following laparotomy. Cervical colposcopic findings were consistent with female genital schistosomiasis. She was successfully treated with praziquantel. CONCLUSION: Female genital schistosomiasis of the upper genital tract can mimic an ovarian malignancy. Hence there is a need for its consideration as a differential diagnosis in patients with non-classical presentations of pelvic tumours in schistosomiasis-endemic areas.


Subject(s)
Ovarian Neoplasms , Praziquantel , Female , Humans , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/pathology , Ovarian Neoplasms/drug therapy , Praziquantel/therapeutic use , Diagnosis, Differential , Young Adult , Anthelmintics/therapeutic use , Schistosomiasis haematobia/diagnosis , Schistosomiasis haematobia/drug therapy , Schistosomiasis/diagnosis , Schistosomiasis/drug therapy , Animals
2.
Contemp Clin Trials Commun ; 15: 100362, 2019 Sep.
Article in English | MEDLINE | ID: mdl-31049462

ABSTRACT

Epilepsy is the most common serious childhood neurological disorder. In the low- and middle-income countries (LMICs) of Africa, children with epilepsy suffer increased morbidity and mortality compared to their counterparts in high-income countries, and the majority do not receive treatment - the childhood epilepsy treatment gap. Reports of the childhood epilepsy treatment gap in Africa are likely underestimates; most surveys do not include several common childhood seizure types, including most types of non-convulsive epilepsy. Efforts to scale up childhood epilepsy care services in the LMICs of Africa must contend with a shortage of physicians and diagnostic technology [e.g., electroencephalograms (EEGs)]. One pragmatic solution is to integrate epilepsy care into primary care by task-shifting to community health extension workers. The aims of this project (BRIDGE) are to: 1) train, develop, and pilot task-shifted epilepsy care teams; 2) develop and pilot innovative childhood epilepsy screening and diagnostic paradigms adapted to the local Hausa language/culture in Kano, northern Nigeria; and, 3) quantify and map the childhood epilepsy treatment gap, using geographic information systems (GIS), to target limited resources to areas of greatest need. Task-shifted teams will diagnose and manage childhood epilepsy using an innovative epilepsy screening tools and diagnostic and management paradigms in environments with limited EEG access. If validated and demonstrated efficacious in clinical trials, this project can be taken to scale across broader areas of west Africa's LMICs that share language and culture. BRIDGE has the potential to enhance access to basic childhood epilepsy care and establish the foundation for childhood epilepsy clinical trials in west Africa.

3.
Niger Postgrad Med J ; 25(3): 156-160, 2018.
Article in English | MEDLINE | ID: mdl-30264766

ABSTRACT

BACKGROUND: Cerebral palsy (CP) is a common neurodevelopmental motor disorder resulting from early childhood brain insult. Nutrition in children is very important for growth and development. This is more so in those with chronic illnesses such as CP. This study was conducted with the aim of assessing the anthropometry and anthropometric indices of CP children. MATERIALS AND METHODS: This comparative, cross-sectional study recruited 150 children with CP matched for age and sex, with 150 children without CP (as controls). The participants' socio-demographic and CP-related data were collected using a pre-tested questionnaire designed for the study. The weight and height of the subjects were measured. Nutritional status was determined using the World Health Organization Z-scores. RESULTS: Overall prevalence of malnutrition in CP subjects was 86%. This was significantly higher than in controls, whose prevalence was 55.3% (χ2 = 34.027,P < 0.0001). The prevalence of stunting, wasting and underweight in CP subjects was 53.3%, 57.5% and 66.9%, respectively. These were also significantly higher than those of controls who had prevalence of stunting being 16.7%, wasting 8.5% and underweight 14.8%. CONCLUSION: This study found a high prevalence of malnutrition (especially under-nutrition) and therefore underscores the need for more emphases on nutritional assessment, counselling and management in CP patients.


Subject(s)
Cerebral Palsy/complications , Malnutrition/etiology , Nutritional Status , Anthropometry , Case-Control Studies , Cerebral Palsy/epidemiology , Child , Child, Preschool , Cross-Sectional Studies , Humans , Malnutrition/epidemiology , Nigeria/epidemiology , Prevalence , Surveys and Questionnaires
4.
Indian J Psychol Med ; 39(4): 407-412, 2017.
Article in English | MEDLINE | ID: mdl-28852230

ABSTRACT

BACKGROUND: Sleep problems, especially in the adolescent stage of development, may be associated with excessive daytime sleepiness, impaired neurocognitive function, and a host of others leading to suboptimal performance. OBJECTIVES: To determine the pattern of sleep problems in school-going adolescents based on the bedtime problems; excessive daytime sleepiness; awakenings during the night and problems falling back asleep; regularity and duration of sleep; sleep-disordered breathing (BEARS) sleep screening algorithm. MATERIALS AND METHODS: This is a cross-sectional descriptive study involving 353 secondary school-going adolescents in Kano metropolis. Subjects were selected for the study using multistage sampling technique. The study lasted from March 2015 to July 2015. Sleep problems were screened for using the BEARS sleep screening algorithm. Tables were used to present the qualitative data. The various BEARS sleep patterns were assessed, and comparison between stages of adolescence was done using Chi-square test (and Fisher's exact test where necessary). A significant association was considered at P < 0.05. RESULTS: Of the 353 adolescents studied, 61.8% were males while 38.2% were females with male, female ratio of 1.6:1. Early, middle, and late adolescents constituted 13.9%, 39.9%, 46.2% respectively. BEARS sleep screening revealed awakenings during the night (34.6%) as the most common sleep-related problem reported, and this was followed by excessive daytime sleepiness (21.0%). Age-group dependent sleep duration was 7.19 ± 1.26, 7.13 ± 1.13, 7.16 ± 1.28, with P > 0.05. Although 62.9% of all the adolescents watched TV/play video games until 1 h before going to bed and this was highest in late adolescence, it was not statistically significantly associated with any of the sleep problems. CONCLUSION: Both the quality and quantity of sleep in Nigerian adolescents in Kano is suboptimal. Adolescent and sleep medicine should receive more attention in our environment.

5.
Niger J Med ; 24(4): 354-62, 2015.
Article in English | MEDLINE | ID: mdl-27487614

ABSTRACT

Tobacco smoking is still one of the most important risk factor for Respiratory and cardiovascular diseases and an estimated 90% of causes of lung cancer are attributable toTobacco smocking and equally 90% of peripheral vascular disease in non-diabetic population is attributable to Tobacco smoking, despite the health effect there is disturbing figures of people who take up smoking habit daily and increase level of failed quit smoking attempts. Environment and genetics still plays major role, and various forms of tobacco is used worldwide and its health consequence has been highlighted. Monitoring tobacco use and prevention policies through effective tax laws is paramount to reduction of the tobacco health effects in our environments.


Subject(s)
Cardiovascular Diseases/etiology , Health Behavior , Pulmonary Disease, Chronic Obstructive/etiology , Smoking/adverse effects , Cardiovascular Diseases/epidemiology , Humans , Lung Neoplasms/etiology , Primary Prevention/organization & administration , Respiratory Tract Neoplasms/etiology , Risk Factors , Smoking/epidemiology , Nicotiana/adverse effects , Urogenital Neoplasms/etiology
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