[Histocompatibility antigens and their role in the pathogenesis of developmental anomalies of the nervous system in children]. / Antigeny gistosovmestimosti i ikh rol' v patogeneze anomalii razvitiia nervnoi sistemy u detei.

Clinical and immunogenetic examinations of 40 patients with congenital diseases of the nervous system and of 10 couples of their parents revealed an association with HLA B12 antigen, HLA homozygosis in the majority of parents and children, and a high level of antigenic stimulation. The results may be considered as markers and criteria of a high risk of development of this disease in children.

[Clinical results of using Nakom in diseases of the nervous system]. / Klinicheskie rezu'ltaty primeneniia Nakoma pri zabolevaniiakh nervnoi sistemy.

Clinical investigation was performed and dopamine metabolism (renal catecholamine excretion) studied in 29 children and 5 adults with various forms of CP, 5 myasthenic children and 1 child with Strümpel disease treated with Nakom. The therapy was judged expedient in 20% of the cases of pronounced muscular rigidity and dystonia with decreased dopamine excretion. The drug proved ineffective in atonic, astatic, severe hyperkinetic arms, and in cases with severe psycho-organic signs.

[Hereditary diseases and developmental disorders of the nervous system in children (clinico-epidemiological study)]. / Nasledstvennye zabolevaniia i poroki razvitiia nervnoi sistemy u detei (kliniko-épidemiologicheskoe issledovanie).

These are data of a clinico-epidemiological investigation into dysontogenesis++ and inherited disorders of the nervous system in children in a major industrial region. The peculiarities of structure, rate, clinical picture, genealogy of the disorders in the population is described. A program of further actions is designed in order to elaborate a complex of preventive measures.