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Arch Pediatr ; 7(7): 745-7, 2000 Jul.
Article in French | MEDLINE | ID: mdl-10941490

ABSTRACT

UNLABELLED: Drug administration during the last trimester of pregnancy may have adverse effects for the newborn. CASE REPORT: A hemolytic anemia occurred during the first hours of life in a full-term neonate whose mother had taken nitrofurantoin during the last month of pregnancy. CONCLUSION: The immature enzymatic systems of the neonate are exposed to this adverse effect and justify the recommendation not to prescribe nitrofurantoin at the end of pregnancy.


Subject(s)
Anemia, Hemolytic/chemically induced , Anti-Infective Agents, Urinary/adverse effects , Infant, Newborn, Diseases/chemically induced , Nitrofurantoin/adverse effects , Adult , Anti-Infective Agents, Urinary/administration & dosage , Female , Humans , Infant, Newborn , Male , Maternal-Fetal Exchange , Nitrofurantoin/administration & dosage , Pregnancy , Pregnancy Complications, Infectious/drug therapy , Pregnancy Trimester, Third , Urinary Tract Infections/drug therapy
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