ABSTRACT
OBJECTIVE: To determine the early and late outcome of percutaneous transluminal angioplasty (PTA) for critical limb ischaemia (CLI) in patients aged 80 years and over. METHODS: Retrospective case note review of all patients aged 80 years and over who underwent attempted PTA for CLI between 1st January 1999 and 31st December 2000. Minimum follow-up was 12 months with a maximum of 42 months. RESULTS: One hundred and twenty-eight PTAs were attempted in 113 severely ischaemic limbs of 98 patients (36 men and 62 women of median age 84, range 80-97, years). Seventy patients had significant co-morbidity. The indication for revascularisation was rest pain in 47 procedures, ulceration in 66 and digital gangrene in 15. The anatomical segments involved were iliac (n=19), superficial femoral (n=92), popliteal (n=91) and infrapopliteal (n=72). The technical success rate was 108 of 128 (84%) procedures. Early technical complications occurred in 24 (19%) procedures: four major, 20 minor. The 30-day operative mortality rate was six of 128 (5%). The median (range) in-hospital stay was two (1-72) days. Early or delayed surgical revascularisation was required in 11 limbs and there were six major limb amputations during the study period. The 24-month patient survival rate was 59%. The 24-month primary and secondary symptomatic patency and secondary limb salvage rates were 52, 69 and 95%, respectively. DISCUSSION: PTA is safe, requires a short hospital stay, and is clinically effective in the majority of very elderly patients with CLI. Although minimally invasive, the relatively high peri-procedural mortality rate and low 24-month survival rate reflect the high co-morbidity of this group of patients.
Subject(s)
Angioplasty, Balloon , Ischemia/therapy , Leg/blood supply , Aged , Aged, 80 and over , Female , Humans , Length of Stay , Male , Vascular PatencyABSTRACT
OBJECTIVE: Evaluating the rate of pregnancies, neonates, implantation rate and kinds of donor in our program Assisted Reproduction with oocyte donation. INTRODUCTION: The oocyte donation is the most important support in assisted reproduction because in patients with ovarian failure, offering the same opportunity to female without ovarian alterations to increase the rate of pregnancies. MATERIAL AND METHOD: 98 donor's procedures were included in host patients; 87 were FIV-TE and 11 GIFT between march to june 1997. The patients were divided in age group: 1) < 30 years, 2) 30 to 34 years, 3) 35 to 39 years, 4) > or = 40 years. The donors were divided in known (26) and unknown (72). The results were analysed. RESULTS: 48 pregnancies (55.17%) of the 87 FIV-TE-D group were obtained with 31 neonates The implantation rate was 17.5% to FIV-TE group and 13.8 to GIFT group, 44 (61.11%) pregnancies were from unknown donors group and 9 (34.61%) from known donors group. CONCLUSIONS: Our results are similar to others international reports, we have observed a little and significative difference between pregnancy with oocytes from known donors and unknown donors; this is the principal motive to be selective in the suitable known donor.
Subject(s)
Oocyte Donation , Adult , Female , Humans , Infant, Newborn , Mexico , Ovarian Hyperstimulation Syndrome , Pregnancy , Tissue DonorsABSTRACT
A molecular linkage map of cultivated oat composed of 561 loci has been developed using 71 recombinant inbred lines from a cross between Avena byzantina cv. Kanota and A. sativa cv. Ogle. The loci are mainly restriction fragment length polymorphisms detected by oat cDNA clones from leaf, endosperm, and root tissue, as well as by barley leaf cDNA clones. The loci form 38 linkage groups ranging in size from 0.0 to 122.1 cM (mean, 39 cM) and consist of 2-51 loci each (mean, 14). Twenty-nine loci remain unlinked. The current map size is 1482 cM and the total size, on the basis of the number of unlinked loci, is estimated to be 2932.0 cM. This indicates that this map covers at least 50% of the cultivated oat genome. Comparisons with an A-genome diploid oat map and between linkage groups exhibiting homoeology to each other indicate that several major chromosomal rearrangements exist in cultivated oat. This map provides a tool for marker-assisted selection, quantitative trait loci analyses, and studies of genome organization in oat.