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6.
Eur J Intern Med ; 25(2): 160-3, 2014 Feb.
Article in English | MEDLINE | ID: mdl-24012324

ABSTRACT

BACKGROUND: Severe hypertriglyceridemia with an accumulation of chylomicrons and triglyceride figures >1000 mg/dL can cause acute pancreatitis, a potentially fatal complication. The option of rapid reduction in triglyceride concentrations is attractive and possible with plasmapheresis. METHODS: We present the results of an analysis of 11 patients admitted to the intensive care unit with severe hypertriglyceridemic pancreatitis and treated with plasmapheresis. The procedure was repeated until serum triglycerides were below 1000 mg/dL. We recorded anthropometric, clinical data as well as final outcome. RESULTS: In eight patients a single plasma exchange was sufficient to reduce triglyceride figures <1000 mg/dL. Only three patients died, all with the worst severity indexes and who experienced the longest delay before the procedure. CONCLUSIONS: Our results, together with a review of the literature, confirm the need for a randomized clinical trial to compare conventional treatment vs. plasmapheresis in patients with severe hypertriglyceridemic pancreatitis.


Subject(s)
Hypertriglyceridemia/therapy , Pancreatitis/therapy , Plasmapheresis , Adult , Alcohol Drinking , Cohort Studies , Female , Humans , Hypertriglyceridemia/complications , Male , Middle Aged , Pancreatitis/etiology , Retrospective Studies , Severity of Illness Index , Treatment Outcome
10.
Med. intensiva (Madr., Ed. impr.) ; 34(9): 629-631, dic. 2010. ilus
Article in Spanish | IBECS | ID: ibc-95465

ABSTRACT

La hipertensión pulmonar es una patología grave con un tratamiento complejo basado en medidas generales, anticoagulación y utilización de fármacos específicos vasodilatadores. La insuficiencia cardiaca derecha instaurada en estadios finales de la enfermedad se trata con diuréticos. Presentamos la ultrafiltración lenta continua como tratamiento en insuficiencia cardiaca derecha secundaria a hipertensión pulmonar asociada a enfermedad del colágeno refractaria a tratamiento diurético (AU)


Pulmonary hypertension is a severe disease with complex treatment based on general measurements, anticoagulation and use of specific vasodilator drugs. Right heart failure initiated in final stages of the disease is treated with diuretics. We present the case of slow continuous ultrafilitration as treatment in right heart failure secondary to pulmonary hypertension associated to collagen disease refractory to diuretic treatment (AU)


Subject(s)
Humans , Pulmonary Heart Disease/therapy , Ultrafiltration/methods , Hypertension, Pulmonary/therapy , Heart Failure/drug therapy , Diuretics/therapeutic use
11.
Med Intensiva ; 34(9): 629-31, 2010 Dec.
Article in Spanish | MEDLINE | ID: mdl-20346544

ABSTRACT

Pulmonary hypertension is a severe disease with complex treatment based on general measurements, anticoagulation and use of specific vasodilator drugs. Right heart failure initiated in final stages of the disease is treated with diuretics. We present the case of slow continuous ultrafilitration as treatment in right heart failure secondary to pulmonary hypertension associated to collagen disease refractory to diuretic treatment.


Subject(s)
CREST Syndrome/complications , Hemofiltration , Hypertension, Pulmonary/therapy , Pulmonary Heart Disease/therapy , Female , Hemofiltration/methods , Humans , Hypertension, Pulmonary/etiology , Middle Aged , Pulmonary Heart Disease/etiology , Time Factors
12.
Med. intensiva (Madr., Ed. impr.) ; 34(1): 74-78, ene.-feb. 2010. ilus, tab
Article in Spanish | IBECS | ID: ibc-80391

ABSTRACT

Presentamos las plasmaféresis (PMF) realizadas en una unidad de cuidados intensivos (UCI) polivalente de 18 camas en el quinquenio comprendido entre los años 2003-2007. El objetivo del presente artículo es comunicar nuestra experiencia en PMF realizada con monitores específicos para tratamientos continuos de reemplazo renal (TCRR) y evidenciar la versatilidad derivada del uso de estos tratamientos y de estos monitores en las UCI. La utilidad de estos procedimientos abarcan muchos escenarios de la enfermedad crítica ingresada en nuestras unidades (pacientes neurológicos, hematológicos, reumatológicos). En definitiva, nuestra experiencia en PMF nos lleva a concluir que es un tratamiento de depuración extracorpórea sencillo, que puede realizar el personal sanitario de cuidados intensivos en cualquier momento dentro de un amplio espectro de indicaciones clínicas, con monitores de TCRR y con unas complicaciones asociadas a la técnica mínimas y leves (AU)


We discuss the plasmapheresis (PE) carried out in an 18-bed polyvalent intensive care unit between the years 2003-2007. This article aims to report our experience in plasmapheresis performed with specific monitors for continuous renal replacement therapy (CRRT) that shows the versatility of the use of these procedures in intensive care. The utility of these procedures include many different critical disease settings in our units (neurology, hematology, and rheumatology patients). In short, our experience in PE has led us to the conclusion that plasmapheresis is a simple extracorporeal depuration treatment that can be performed by staff trained in intensive care at any moment within a wide spectrum of clinical indications, with CRRT monitors and with minimum adverse effects (AU)


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Plasmapheresis/statistics & numerical data , Intensive Care Units/statistics & numerical data , Plasmapheresis , Retrospective Studies , Spain , Hospitals, University/statistics & numerical data
13.
Med Intensiva ; 34(1): 74-8, 2010.
Article in Spanish | MEDLINE | ID: mdl-19837481

ABSTRACT

We discuss the plasmapheresis (PE) carried out in an 18-bed polyvalent intensive care unit between the years 2003-2007. This article aims to report our experience in plasmapheresis performed with specific monitors for continuous renal replacement therapy (CRRT) that shows the versatility of the use of these procedures in intensive care. The utility of these procedures include many different critical disease settings in our units (neurology, hematology, and rheumatology patients). In short, our experience in PE has led us to the conclusion that plasmapheresis is a simple extracorporeal depuration treatment that can be performed by staff trained in intensive care at any moment within a wide spectrum of clinical indications, with CRRT monitors and with minimum adverse effects.


Subject(s)
Critical Care/methods , Plasmapheresis/statistics & numerical data , Adolescent , Adult , Aged , Aged, 80 and over , Autoimmune Diseases/therapy , Female , Hemolytic-Uremic Syndrome/therapy , Hospitals, University/statistics & numerical data , Humans , Intensive Care Units/statistics & numerical data , Male , Middle Aged , Pancreatitis/therapy , Purpura, Thrombotic Thrombocytopenic/therapy , Renal Replacement Therapy/instrumentation , Retrospective Studies , Spain , Treatment Outcome , Vasculitis/therapy , Young Adult
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