Level function levels and oxidative stress markers in patients with multidrug-resistant tuberculosis in the Brazilian Amazon.

This study aimed to correlate the values of liver markers with oxidative stress markers in patients with multidrug-resistant tuberculosis in the Brazilian Amazon. A total of 30 patients from the Tuberculosis clinic of a referral hospital were admitted to the study. Whole blood samples were collected for analysis of liver enzyme values and oxidative stress markers by spectrophotometry. The prevalence was male (60%) and the 18-29 age group was the most affected. Patients with multidrug-resistant tuberculosis presented catalase values with a median equal to 6.94 U/gHb and for glutathione, the median was equal to 14.76 µg∕ml. As for the values of liver enzymes (AST, ALT, Gamma-GT and Alkaline phosphatase) the patients had medians equal to 60.50 (U/L); 80 (U/L); 54 (U/L); and 100 (U/L) respectively (p<0.0001). The results suggest a hepatotoxic effect of the drug, which recommends further studies with a larger number of samples in order to investigate the predictors of liver damage in patients with multidrug-resistant tuberculosis.

[Nursing care: a phenomenological view of the leukemic patient]. / O cuidado de enfermagem: uma visão fenomenológica do ser leucêmico.

The present investigation approaches the nursing care process from the patient with leukemia perspective. The author departs from the feeling of uneasiness emerged in her quotidian either as a nurse practitioner and nursing professor and seeks to apprehend the sense of care within the everyday existence of the leukemic patient as a world-inserted human being. Also, the author presents reflexions on the path to be followed and finds an appropriate method to disclose the subjects veiled discourse based either in the phenomenological qualitative methodology and Heideggerian Hermeneutics; thus, the mode by which nursing care is perceived by the leukemic patient may be seen as a non-authentic from of being-with, have the nursing care delivered in a distinctive way, care given with patience and understanding, and receive that same type of care as an authentic form of being-with. By uncovering the sense emerged through those speeches, the investigator is likely to re-learn the care required to be provided in accordance with the studied subjects speech.