ABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Gastrointestinal Hemorrhage/etiology , Liver Cirrhosis/complications , Varicose Veins/complications , Gallbladder Diseases/complications , Gallbladder Diseases/diagnostic imaging , Fatal OutcomeABSTRACT
Liver cirrhosis is a disease related to numerous severe complications such as portal hypertension or collateral circulation. Varices that are located outside the gastroesophageal region (ectopic varices) such as the anorectal region, colon, ileum or gallbladder are unusual. In many cases, they are related to the existence of portal vein thrombosis. We report the case of a patient with a severe hemorrhage of gallbladder varices due to alcohol-related cirrhosis.
Subject(s)
Gallbladder/blood supply , Hemorrhage/etiology , Liver Cirrhosis/complications , Varicose Veins/complications , Fatal Outcome , Gallbladder/diagnostic imaging , Hemoperitoneum/diagnostic imaging , Hemoperitoneum/therapy , Hemorrhage/diagnostic imaging , Humans , Liver Cirrhosis/diagnostic imaging , Male , Middle Aged , Varicose Veins/diagnostic imagingABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Echinococcosis, Hepatic/complications , Hypertension, Portal/physiopathology , Magnetic Resonance Spectroscopy/methods , Computed Tomography Angiography/methods , Gastrointestinal HemorrhageSubject(s)
Echinococcosis, Hepatic/complications , Hypertension, Portal/etiology , Adrenergic beta-Antagonists/therapeutic use , Adult , Albendazole/therapeutic use , Anthelmintics/therapeutic use , Computed Tomography Angiography , Echinococcosis, Hepatic/diagnostic imaging , Echinococcosis, Hepatic/surgery , Elective Surgical Procedures , Esophageal and Gastric Varices/etiology , Gastrointestinal Hemorrhage/etiology , Hepatectomy , Humans , Magnetic Resonance Imaging , Male , RecurrenceABSTRACT
BACKGROUND/AIMS: The objective of our study was to determine the epidemiological, laboratory, and serological characteristics of patients with chronic hepatitis B virus (HBV) infection and normal transaminases. The study also aimed to evaluate liver damage by measuring the liver fibrosis (LF) grade and to identify possible factors associated with the presence of fibrosis. METHODS: A retrospective observational study was conducted in patients with chronic HBV infection and classified as inactive carriers or immune-tolerant. Epidemiological variables of age, sex, immigrant, alcohol consumption, and body mass index (BMI), as well as virological variables (HBV DNA) and transaminase level were collected throughout the follow-up. The LF grade was evaluated by transient elastography. The cutoff value for significant fibrosis (SF) was liver stiffness ≥7.9 kPa. RESULTS: A total of 214 patients were included in the analysis, and 62% of them had a BMI ≥25 kg/m². During follow-up, 4% of patients showed transaminase elevation ( < 1.5 times normal). Most patients had a viral DNA level < 2,000 IU/mL (83%). Data on LF were available in 160 patients; of these, 14% had SF, 9% F3, and 6% F4. The variables associated with the presence of SF were transaminase alteration during follow-up, as 23% of patients with SF had elevated transaminases versus 3% of patients without SF (P < 0.005), and BMI, as the vast majority of patients with SF (88%) had a BMI ≥25 kg/m² versus 56% of patients without SF (P < 0.05). CONCLUSIONS: In patients with chronic HBV infection and normal transaminases, liver damage does not seem to be related to DNA levels, alcohol consumption, or immigrant status. SF seems to be associated with transaminase alteration during follow-up and elevated BMI. It is therefore recommended to measure LF grade with validated non-invasive methods in such patients.
Subject(s)
Humans , Alcohol Drinking , Body Mass Index , DNA , DNA, Viral , Elasticity Imaging Techniques , Emigrants and Immigrants , Fibrosis , Follow-Up Studies , Hepatitis B e Antigens , Hepatitis B, Chronic , Hepatitis, Chronic , Liver Cirrhosis , Liver , Observational Study , Retrospective Studies , TransaminasesABSTRACT
No disponible
Subject(s)
Humans , Female , Aged, 80 and over , Histiocytosis, Langerhans-Cell/diagnosis , Colonic Neoplasms/diagnosis , Abdominal Pain/etiology , Colonoscopy , Diagnosis, DifferentialABSTRACT
No disponible