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1.
J Thorac Dis ; 15(10): 5605-5612, 2023 Oct 31.
Article in English | MEDLINE | ID: mdl-37969290

ABSTRACT

Background: Rapid deployment aortic valve replacement (RD-AVR) has been recently introduced with encouraging results. Outcomes of isolated RD-AVR include good hemodynamic profile, facilitation of minimally invasive techniques, and reduction of surgical times. However, role of this prosthesis in concomitant surgery is not well known. Methods: In 2016, we formed a registry to monitor the introduction of this prosthesis, RApid Deployment Aortic Replacement (RADAR). We aim to report mid-term outcomes focusing on patients who had RD-AVR combined with other surgical procedures. Results: Between July 2012 and February 2021, 370 patients were included in this registry (mean age, 75.8±8.0 years; 64.32% male; mean EuroSCORE II, 3.5±2.8). Of these, 128 (34.59%) had concomitant procedures including myocardial revascularization surgery in 69 patients (53.91%), surgery on the ascending aorta in 34 (26.56%), and procedures on other valves in 10 patients (7.81%). There were no significant differences between the isolated AVR and concomitant AVR groups in postoperative complications, in-hospital mortality (4.72% vs. 3.32%, P=0.524), or hemodynamic behavior of these prostheses. Three-year survival was 83.73% and 89.89% in the isolated and concomitant AVR group respectively. There was no difference in survival between the two groups (log-rank test, P=0.4124). Conclusions: Our results support the safety and efficacy of the Edwards INTUITY valve system even in complex aortic valve disease with additional cardiac procedures. RD-AVR could become a useful tool for concomitant surgeries where surgical times are expected to be prolonged.

2.
Cardiovasc Pathol ; 28: 59-63, 2017.
Article in English | MEDLINE | ID: mdl-28334596

ABSTRACT

Valvular hemangioma incidence is extremely low. In this report, we describe a 62-year-old man who presented with mild edema of the lower limbs. An echocardiogram revealed an incidental 1.3-cm diameter mass on the anterior mitral valve leaflet for which he underwent surgical resection and mitral valve replacement. Histopathological examination showed a lymphocyte-rich capillary-cavernous hemangioma. The exuberant lymphoid stroma is unusual for hemangioma and represents an undescribed pattern of cardiac hemangioma. Including the present report, only 13 cases of mitral valve hemangioma have been reported to date. Most patients are adult. Mitral hemangioma originates in the atrial aspect of the valve and involves more commonly the anterior leaflet. The average maximum diameter of the lesion is 1.7 (S.D.=0.75) cm. Pure cavernous hemangioma is the predominant type of mitral hemangioma. Most of them are described as pedunculated or polypoid. Surgical excision appears to be curative. Recurrences have not been reported. Lymphocyte-rich cardiac hemangioma represents a peculiar type of hemangioma which should be included in the differential diagnosis of other vascular lesions.


Subject(s)
Heart Neoplasms/pathology , Hemangioma, Capillary/pathology , Hemangioma, Cavernous/pathology , Lymphocytes, Tumor-Infiltrating/pathology , Mitral Valve/pathology , Biomarkers, Tumor/analysis , Biopsy , Echocardiography , Heart Neoplasms/chemistry , Heart Neoplasms/immunology , Heart Neoplasms/surgery , Heart Valve Prosthesis Implantation , Hemangioma, Capillary/chemistry , Hemangioma, Capillary/immunology , Hemangioma, Capillary/surgery , Hemangioma, Cavernous/chemistry , Hemangioma, Cavernous/immunology , Hemangioma, Cavernous/surgery , Humans , Immunohistochemistry , Incidental Findings , Lymphocytes, Tumor-Infiltrating/chemistry , Lymphocytes, Tumor-Infiltrating/immunology , Male , Middle Aged , Mitral Valve/chemistry , Mitral Valve/immunology , Mitral Valve/surgery , Treatment Outcome
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