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1.
J Cutan Pathol ; 48(2): 322-324, 2021 Feb.
Article in English | MEDLINE | ID: mdl-32779208

ABSTRACT

Rhabdomyomatous mesenchymal hamartoma (RMH), also known as congenital midline hamartoma and striated muscle hamartoma, is a rare congenital malformation presenting most commonly in midline sites of the head and neck region. Since its first description in 1986, 67 cases have been reported to date. We report a case of RMH presenting as a chin nodule in an otherwise healthy 15-year-old male. The patient presented with a dome-shaped subcutaneous lesion on his chin which had been present since birth, but had grown and was interfering with his ability to shave. He otherwise had no history of congenital anomalies or malformations. Histopathological examination of the excised lesion revealed a haphazard proliferation of striated muscle admixed with adipose tissue and adnexal structures within the dermis and subcutaneous tissue, consistent with a diagnosis of RMH. While the majority of reported cases are of newborns or children under 3 years of age, RMH may not come to clinical attention until later in life. This rare malformation should be included in the differential diagnosis of lesions containing dermal striated muscle and/or adipose tissue, to include nevus lipomatosus superficialis, fibrous hamartoma of infancy, neuromuscular choristoma, fetal rhabdomyoma, and rhabdomyosarcoma.


Subject(s)
Facial Neoplasms , Hamartoma , Rhabdomyoma , Skin Neoplasms , Adolescent , Facial Neoplasms/diagnosis , Facial Neoplasms/metabolism , Facial Neoplasms/pathology , Hamartoma/diagnosis , Hamartoma/metabolism , Hamartoma/pathology , Humans , Male , Rhabdomyoma/diagnosis , Rhabdomyoma/metabolism , Rhabdomyoma/pathology , Skin Neoplasms/diagnosis , Skin Neoplasms/metabolism , Skin Neoplasms/pathology
2.
JAAD Case Rep ; 6(11): 1182-1184, 2020 Nov.
Article in English | MEDLINE | ID: mdl-33163603
3.
Dermatol Online J ; 20(1): 21252, 2014 Jan 15.
Article in English | MEDLINE | ID: mdl-24456955

ABSTRACT

Traumatic neuromas are tumors produced by a reactive process to regenerate injured nerves that result in a disordered proliferation of nerve bundles. These tumors are usually related to previous surgery or trauma. We describe a case of traumatic neuroma on the penis of a 24-year-old man; the tumor was initially suspected to be a condyloma. A shave biopsy was both diagnostic and curative.


Subject(s)
Neuroma/etiology , Penile Neoplasms/etiology , Penis/injuries , Biopsy , Condylomata Acuminata/diagnosis , Dermis/blood supply , Dermis/innervation , Dermis/pathology , Diagnosis, Differential , Epidermis/pathology , Humans , Male , Mechanoreceptors/ultrastructure , Neuroma/diagnosis , Neuroma/surgery , Penile Neoplasms/diagnosis , Penile Neoplasms/surgery , Young Adult
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