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1.
Ann Pathol ; 43(6): 491-494, 2023 Nov.
Article in French | MEDLINE | ID: mdl-37716866

ABSTRACT

We report a case of primary melanoma of a female urethra diagnosed at a non-metastatic stage in a 48-year-old patient with a history of breast carcinoma treated with radiotherapy and hormone therapy. The patient was consulting for dysuria, hematuria, and perineal pain. The clinical examination found a prolapsed and black mass, developed at the expense of the urethra and located at the anterosuperior part of the vulva. The mass biopsy revealed a proliferation of fusiform and globular cells loaded with black pigment expressing the anti-HMB 45 and PS 100 antibodies. The extension assessment showed an absence of secondary localization. The patient underwent total cystourethrectomy without inguinal lymphadenectomy. There was no recurrence observed on day 100 following the surgery.


Subject(s)
Breast Neoplasms , Melanoma , Urethral Neoplasms , Humans , Female , Middle Aged , Urethra/pathology , Urethra/surgery , Urethral Neoplasms/diagnosis , Urethral Neoplasms/pathology , Urethral Neoplasms/surgery , Melanoma/pathology , Vulva/pathology
2.
Urol Case Rep ; 48: 102419, 2023 May.
Article in English | MEDLINE | ID: mdl-37223405

ABSTRACT

Epidermoid cyst is an unusual and very rarely described lesion in the kidney. We report the case of a 45-year-old woman with no known pathological history who presented with right flank pain accompanied by macroscopic hematuria. The physical examination was unremarkable. The CT scan evoked a malignant tumor in front of a right renal mass with irregular contours. The patient underwent a total right nephrectomy. The nephrectomy specimen received for pathological examination showed macroscopically an encapsulated cystic mass of 4 cm long axis. The cyst lumen was occupied by solid brownish tissue debris. Histologically, the cystic wall was lined by a keratinizing squamous epithelium with accumulation of keratin lamellae in the cystic lumen. Anatomopathological examination concluded to the diagnosis of renal epidermoid cyst.

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