ABSTRACT
AIMS: To assess predictors of non-HDL cholesterol in children and adolescents with T1DM. METHODS: A cross-sectional study of 120 children and adolescents aged 7-16 with T1DM, but without any other chronic morbidities, at a referral outpatient clinic for the treatment of diabetes in Rio de Janeiro, Brazil. Socio-demographic, anthropometric, dietary, and clinical factors were assessed, which included measurements of serum lipids and glycated hemoglobin (HbA1c). Food intake was assessed by 24-h dietary recall. Multiple linear regression was adopted in the analysis. RESULTS: The mean age of of the subjects was 11.74⯱â¯2.88â¯years, 53.3% were female, and the mean duration of T1DM was 6.68⯱â¯3.33â¯years. The mean energy intake from carbohydrates, proteins, and lipids was 51.98% (±9.20), 21.43% (±6.13), and 26.57% (±9.98), respectively. The energy intake from processed and ultra-processed foods represented 40.79% of total energy intake. The predictors of non-HDL cholesterol were: HbA1c (%) (pâ¯=â¯0.000, ßâ¯=â¯8.5, CI: 4.8-12.1), duration of T1DM (pâ¯=â¯0.000, ßâ¯=â¯2.8, CI: 1.3-4.3), and sex (pâ¯=â¯0.032, ßâ¯=â¯10.1, CI: 0.9-19.4). CONCLUSION: Glycemic control was the major modifiable predictor of non-HDL cholesterol concentrations, a significant indicator of cardiovascular risk.