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2.
Quad Sclavo Diagn ; 17(1): 31-9, 1981 Mar.
Article in Italian | MEDLINE | ID: mdl-6796990

ABSTRACT

This study reports the immunoelectrophoretic analysis performed on 95 samples of urinary proteins. This analysis shows that in the majority of cases the migrant proteins in gamma position are F(ab) and Fc fragments, and free light chains with a molecular weight between 70,000 and 10,000. There is evidence of an increase in the immunoglobulinic fragments during inflammatory processes and their disappearance afterwards. This phenomenon proves that the elimination of these fragments evidences an increased synthesis of immunoglobulins and consequently also an increased catabolism.


Subject(s)
Blood Proteins/analysis , Immunoglobulin Fragments/analysis , Lung Diseases/immunology , Lung Neoplasms/immunology , Proteinuria , Tuberculosis, Pulmonary/immunology , Acute Disease , Humans , Immunoelectrophoresis , Immunoglobulin Fab Fragments/analysis , Immunoglobulin Fc Fragments/analysis , Immunoglobulin Light Chains/analysis , Urine/analysis
4.
Quad Sclavo Diagn ; 14(2): 178-85, 1978 Jun.
Article in Italian | MEDLINE | ID: mdl-751095

ABSTRACT

A report is given about the synthesis of IgG immunoglobulins in the pleural infiltrations. The quantity of immunoglobulins locally yielded is estimated through the ratio IgG/Albumin in the blood and in the infiltration. Evidence is given that the mechanic and neoplastic transudates are easily detectable on account of the failed local synthesis of immunoglobulins of IgG type. A short account is given of the local synthesis of IgA.


Subject(s)
Immunoglobulins/biosynthesis , Pleural Effusion/immunology , Humans , Immunoglobulin A/analysis , Immunoglobulin A/biosynthesis , Immunoglobulin G/analysis , Immunoglobulin G/biosynthesis , Immunoglobulins/analysis , Serum Albumin/analysis
5.
Quad Sclavo Diagn ; 13(4): 449-57, 1977 Dec.
Article in Italian | MEDLINE | ID: mdl-614605

ABSTRACT

The pleural fluids of 40 patients have been examined. Out of 15 cases of pulmonary cancer the presence of the secretory piece has been noted in 10 cases and its absence in the remaining 25 cases of nonneoplastic pathogenesis. Through the bidimensional immunoelectrophoresis the presence both of a slow IgA fraction (L) and of a fast one (V) has been noted.


Subject(s)
Immunoglobulin A , Immunoglobulin Fragments , Pleural Effusion/immunology , Secretory Component , Humans , Immunoelectrophoresis , Immunoglobulin A/analysis , Immunoglobulin Fragments/analysis , Lung Neoplasms/complications , Lung Neoplasms/immunology , Pleural Effusion/etiology , Secretory Component/analysis
6.
Quad Sclavo Diagn ; 13(4): 504-12, 1977 Dec.
Article in Italian | MEDLINE | ID: mdl-614610

ABSTRACT

A report is given about the opportunity and the advantages of combining the traditional scheme for the study of the pathological immunoglobulins with the analysis of the uncoupling of the bow of precipitation against IgG and the isolation of the pathological immunoglobulin through a diluition of the serum such as to bring the fraction electrophoretically dispersed to not detectable levels and make it detectable the monoclonae portion electrophoretically homogeneous.


Subject(s)
Hypergammaglobulinemia/diagnosis , Immunoglobulins/analysis , Humans , Immunoelectrophoresis , Precipitin Tests
7.
Ann Sclavo ; 19(4): 835-43, 1977.
Article in Italian | MEDLINE | ID: mdl-616249

ABSTRACT

A simple technique of electroimmunodiffusion is described, which is fit for identifying the variations in the ratio IgG/Albumin in the spinal fluid (liquor). Furthermore a general scheme for the survey of the proteic situation in the spinal fluid is also proposed.


Subject(s)
Cerebrospinal Fluid Proteins/analysis , Albumins/cerebrospinal fluid , Electrophoresis, Agar Gel/methods , Humans , Immunoelectrophoresis/methods , Immunoglobulins/cerebrospinal fluid , Serum Albumin/analysis
8.
Ann Sclavo ; 18(2): 364-71, 1976.
Article in Italian | MEDLINE | ID: mdl-1015871

ABSTRACT

Study of the relationships between the variations of the connections between the components of the bronchial secretion and the viscosity of the sputum, with particular regard to the role of the IgA IIS and to the secretory piece.


Subject(s)
Immunoglobulins/isolation & purification , Sputum/immunology , Antibody Formation , Bronchi/immunology , Bronchi/metabolism , Humans , Immunoglobulin A/isolation & purification , Immunoglobulin M/isolation & purification , Viscosity
9.
Ann Sclavo ; 18(2): 357-63, 1976.
Article in Italian | MEDLINE | ID: mdl-1087870

ABSTRACT

Synthesis of a study of the proteins outline of the bronchial secretion with the qualitative and quantitative determination of six protein fractions (albumin, Alfa-antitrypsin, acid Alfa-glycoprotein, haptoglobin, transferrin); comparation of the concentration of these fractions of the expectoration with those of the serum of the patient himself.


Subject(s)
Proteins/metabolism , Sputum/metabolism , Albumins/metabolism , Bronchitis/metabolism , Chronic Disease , Counterimmunoelectrophoresis , Glycoproteins/metabolism , Haptoglobins/metabolism , Humans , Solubility , Transferrin/metabolism , Water , alpha 1-Antitrypsin/metabolism
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