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Mutations Associated with SARS-CoV-2 Variants of Concern, Benin, Early 2021.
Sander, Anna-Lena; Yadouleton, Anges; de Oliveira Filho, Edmilson F; Tchibozo, Carine; Hounkanrin, Gildas; Badou, Yvette; Adewumi, Praise; René, Keke K; Ange, Dossou; Sourakatou, Salifou; Sedjro, Eclou; Aïssi, Melchior A J; Fidelia, Hinson; Djingarey, Mamoudou Harouna; Nagel, Michael; Jo, Wendy Karen; Moreira-Soto, Andres; Drosten, Christian; Landt, Olfert; Corman, Victor Max; Hounkpatin, Benjamin; Drexler, Jan Felix.
Emerg Infect Dis ; 27(11): 2889-2903, 2021 11.
Article in English | MEDLINE | ID: mdl-34463240

ABSTRACT

Intense transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa might promote emergence of variants. We describe 10 SARS-CoV-2 lineages in Benin during early 2021 that harbored mutations associated with variants of concern. Benin-derived SARS-CoV-2 strains were more efficiently neutralized by antibodies derived from vaccinees than patients, warranting accelerated vaccination in Africa.


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COVID-19 , SARS-CoV-2 , Benin/epidemiology , Humans , Mutation
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