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Methods Mol Biol ; 1986: 123-152, 2019.
Article in English | MEDLINE | ID: mdl-31115887

ABSTRACT

A typical characteristic of microarray data is that it has a very high number of features (in the order of thousands) while the number of examples is usually less than 100. In the context of microarray classification, this poses a challenge for machine learning methods, which can suffer overfitting and thus degradation in their performance. A common solution is to apply a dimensionality reduction technique before classification, to reduce the number of features. This chapter will be focused on one of the most famous dimensionality reduction techniques: feature selection. We will see how feature selection can help improve the classification accuracy in several microarray data scenarios.


Subject(s)
Algorithms , Oligonucleotide Array Sequence Analysis/methods , Bayes Theorem , Databases, Genetic , Support Vector Machine
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