A test of pre-exposure spacing and multiple context pre-exposure on the mechanisms of latent inhibition of dental fear: A study protocol.

BACKGROUND: Latent inhibition occurs when exposure to a stimulus prior its direct associative conditioning impairs learning. Results from naturalistic studies suggest that latent inhibition disrupts the learning of dental fear from aversive associative conditioning and thereby reduces the development of dental phobia. Although theory suggests latent inhibition occurs because pre-exposure changes the expected relevance and attention directed to the pre-exposed stimulus, evidence supporting these mechanisms in humans is limited. The aim of this study is to determine if two variables, pre-exposure session spacing and multiple context pre-exposure, potentiate the hypothesized mechanisms of expected relevance and attention and, in turn, increase latent inhibition of dental fear. METHODS: In a virtual reality simulation, child and adult community members (ages 6 to 35) will take part in pre-exposure and conditioning trials, followed by short- and long-term tests of learning. A 100ms puff of 60 psi air to a maxillary anterior tooth will serve as the unconditioned stimulus. Pre-exposure session spacing (no spacing vs. sessions spaced) and multiple context pre-exposure (single context vs. multiple contexts) will be between-subject factors. Stimulus type (pre-exposed to-be conditioned stimulus, a non-pre-exposed conditioned stimulus, and an unpaired control stimulus) and trial will serve as within-subject factors. Baseline pain sensitivity will also be measured as a potential moderator. DISCUSSION: It is hypothesized that spaced pre-exposure and pre-exposure in multiple contexts will increase the engagement of the mechanisms of expected relevance and attention and increase the latent inhibition of dental fear. It is expected that the findings will add to theory on fear learning and provide information to aid the design of future interventions that leverage latent inhibition to reduce dental phobia.

A study protocol testing pre-exposure dose and compound pre-exposure on the mechanisms of latent inhibition of dental fear.

BACKGROUND: Dental stimuli can evoke fear after being paired - or conditioned - with aversive outcomes (e.g., pain). Pre-exposing the stimuli before conditioning can impair dental fear learning via a phenomenon known as latent inhibition. Theory suggests changes in expected relevance and attention are two mechanisms responsible for latent inhibition. In the proposed research, we test whether pre-exposure dose and degree of pre-exposure novelty potentiate changes in expected relevance and attention to a pre-exposed stimulus. We also assess if the manipulations alter latent inhibition and explore the possible moderating role of individual differences in pain sensitivity. METHODS: Participants will be healthy individuals across a wide range of ages (6 to 35 years), from two study sites. Participants will undergo pre-exposure and conditioning followed by both a short-term and long-term test of learning, all in a novel virtual reality environment. The unconditioned stimulus will be a brief pressurized puff of air to a maxillary anterior tooth. Pre-exposure dose (low vs. high) and pre-exposure novelty (element stimulus vs. compound stimuli) will be between-subject factors, with stimulus type (pre-exposed to-be conditioned stimulus, a non-pre-exposed conditioned stimulus, and an unpaired control stimulus) and trial as within-subject factors. Pain sensitivity will be measured through self-report and a cold pressor test. It is hypothesized that a larger dose of pre-exposure and compound pre-exposure will potentiate the engagement of the target mechanisms and thereby result in greater latent inhibition in the form of reduced fear learning. Further, it is hypothesized that larger effects will be observed in participants with greater baseline pain sensitivity. DISCUSSION: The proposed study will test whether pre-exposure dose and compound stimulus presentation change expected relevance and attention to the pre-exposed stimulus, and thereby enhance latent inhibition of dental fear. If found, the results will add to our theoretical understanding of the latent inhibition of dental fear and inform future interventions for dental phobia prevention.

Mothers' Psychological Control and Accommodation are Associated with More Severe Anxiety in Hispanic Youth.

Psychological accommodation and control may help explain the finding that anxiety is more severe and common in Hispanic youth. Research with White samples conceptualizes psychological control as part of an authoritarian parenting style; however, research with Hispanic families suggests that psychological control is more likely to be indicative of a protective parenting style. Based on these findings, we hypothesized that in Hispanic families, psychological control would be related to protective parenting behaviors that ultimately maintain child anxiety. We tested a cross-sectional model hypothesizing that in Hispanic families the link between ethnicity and anxiety would be mediated through psychological control and parental accommodation of child anxiety, a parenting behavior which protects the child from the aversive experiences in the moment but ultimately serves to maintain child anxiety. A sample of mothers (n = 145; 48% Hispanic) and fathers (n = 59; 48% Hispanic) of youth from 8 to 18 years of age completed a survey assessing anxiety and parenting. With Hispanic mothers, the relation between ethnicity (Hispanic/non-Hispanic) and child anxiety was mediated through psychological control and accommodation. With fathers, although control was related to accommodation which, in turn, was related to child anxiety, ethnicity was not associated with control, accommodation, or child anxiety. Findings suggest that the context of parenting behavior should be considered in research, and adaptations of child anxiety treatments should consider ways to allow parents to express their desire to communicate warmth and protectiveness while avoiding negative reinforcement of child anxiety.

Study protocol of an investigation of attention and prediction error as mechanisms of action for latent inhibition of dental fear in humans.

BACKGROUND: Evidence suggests that dental anxiety and phobia are frequently the result of direct associative fear conditioning but that pre-exposure to dental stimuli prior to conditioning results in latent inhibition of fear learning. The mechanisms underlying the pre-exposure effect in humans, however, are poorly understood. Moreover, pain sensitivity has been linked to dental fear conditioning in correlational investigations and theory suggests it may moderate the latent inhibition effect, but this hypothesis has not been directly tested. These gaps in our understanding are a barrier to the development of evidence-based dental phobia prevention efforts. METHODS: Healthy volunteers between the ages of 6 and 35 years will be enrolled across two sites. Participants will complete a conditioning task in a novel virtual reality environment, allowing for control over pre-exposure and the examination of behaviour. A dental startle (a brief, pressurized puff of air to a tooth) will serve as the unconditioned stimulus. Using a within-subjects experimental design, participants will experience a pre-exposed to-be conditioned stimulus, a non-pre-exposed to-be conditioned stimulus, and a neutral control stimulus. Two hypothesized mechanisms, changes in prediction errors and attention, are expected to mediate the association between stimulus condition and fear acquisition, recall, and retention. To ascertain the involvement of pain sensitivity, this construct will be measured through self-report and the cold pressor task. DISCUSSION: Dental phobia negatively affects the dental health and overall health of individuals. This study aims to determine the mechanisms through which pre-exposure retards conditioned dental fear acquisition, recall, and retention. A randomized control trial will be used to identify these mechanisms so that they can be precisely targeted and maximally engaged in preventative efforts.

Development of a Measure of Fearful Implicit Associations with Dental Stimuli in Youth.

Youth with dental anxiety are at an increased risk of poor oral health but current tools used to identify dental anxiety in children in clinical settings are hampered by several limitations. This study assessed the psychometric properties of a measure of implicit associations with dental stimuli, the Affective Misattribution Procedure for dental stimuli (AMP-D) in 68 youth between the ages of 9 and 17 years. Measures of self-reported dental anxiety and parental perceptions of child dental anxiety were also administered. The internal consistency of the AMP-D was high (KR-20 = 0.96) and 1-week test-retest reliability was in the acceptable range (r = 0.75). The AMP-D was correlated with self-reported dental anxiety, providing evidence of construct validity. The psychometric properties of the AMP-D suggest it could be a useful tool in identifying youth with dental anxiety, particularly when concerns regarding self-representation may compromise the validity of self-reported anxiety.

Coping competence and hopelessness moderate the influence of perceived burdensomeness on suicidal ideation in undergraduate college students.

According to the interpersonal theory of suicide, the perception of imposing a burden on loved ones increases the risk for suicidal ideation. Little research, however, has examined the interaction of burdensomeness with cognitive variables in predicting suicidal ideation in college students even though the relationship between burdensomeness and ideation may be contingent on levels of cognitive risk factors. The present study thus examined the relationships between burdensomeness, hopelessness, coping competence, and suicidal ideation. Questionnaires were administered to 279 undergraduate students from a university in the Midwest United States. After controlling for depression, hopelessness, and coping competence, burdensomeness significantly predicted ideation and accounted for variance above and beyond the control variables. Moreover, the relationship between burdensomeness and suicidal ideation was significantly moderated by coping competence and hopelessness. The findings suggest that perceived burdensomeness plays a critical role in the risk for suicide in college students. More specifically, the findings suggest that coping competence and hopelessness can be ideal targets for interventions as changes in these variables may attenuate the association between perceived burdensomeness and suicidal ideation.

An Association Between Perceived Social Support and Posttraumatic Stress Symptom Severity Among Women With Lifetime Sexual Victimization: The Serial Mediating Role of Resilience and Coping.

This study examined the association between perceived social support and severity of posttraumatic stress symptoms, serially mediated by resilience and coping among women exposed to different patterns of sexual victimization experiences: childhood sexual abuse (CSA) only, adult sexual assault (ASA) only, and sexual revictimization (SR). A total of 255 sexually victimized women recruited from four U.S. universities completed self-report measures online; 112 participants reported provisionally diagnosable levels of symptoms of posttraumatic stress disorder (PTSD). The proposed model was largely supported in the CSA only group and the SR group. Different patterns of mediational effects were found across the three groups. Clinical and theoretical implications are discussed.

Latino and Non-Latino Parental Treatment Preferences for Child and Adolescent Anxiety Disorders.

There is frequently a presumption that Latino parents have a greater preference for involvement in their child's treatment for anxiety compared to non-Latino white parents. However, parent involvement may increase burdens associated with treatment and research suggests that Latino individuals already face significantly greater barriers to obtaining mental health treatment. In the current study, we compared Latino and non-Latino parents' preferences for parental involvement and perceptions of burdens in cognitive behavioral therapy (CBT) for youth anxiety. 117 parents (57 Latino) completed measures to assess child anxiety, perceptions of treatment involvement, and burdens associated with treatment. There were no significant differences between Latino and non-Latino parents except for a trend toward Latino parents reporting more concerns about the feasibility of obtaining CBT for their child's anxiety. Because Latino parents expressed concern about potential treatment barriers, cultural adaptations for treatment should focus on decreasing burdens associated with treatment rather than increasing parental involvement.

Dental anxiety: An understudied problem in youth.

Dental anxiety and dental phobia typically emerge during childhood; the associated avoidance of dental care can result in oral health problems and is associated with lower quality of life. In this review, we discuss the definition of dental phobia and dental anxiety and issues related to their differentiation. We then review the literature on dental anxiety and dental phobia, including its prevalence, assessment, and sequalae. Moreover, we provide a synthesis of findings on the etiology and maintenance of dental phobia and propose a comprehensive cognitive behavioral model to guide further study. We also present a systematic qualitative and a quantitative review of the treatment literature, concluding that although we have made strides in learning how to prevent dental anxiety in youth, the methods effective in preventing anxiety may not be equally effective in treating youth with dental phobia. We propose a multidisciplinary approach, including those with expertise in pediatric anxiety as well as pediatric dentistry, is likely required to move forward.

Religion-based emotional social support mediates the relationship between intrinsic religiosity and mental health.

Although previous research suggests that increased religiosity is associated with better mental health and many authors have conjectured that religion-based social support may help explain this connection, scant research has directly examined whether religion-based support mediates religiosity and mental health. The present study examined whether various dimensions of religion-based support (social interaction, instrumental, and emotional) mediated the relationship between religiosity and mental health in college students in the Midwest United States. As expected, of the support dimensions, perceived emotional support was the strongest predictor of decreased hopelessness, depression, and suicide behaviors; and the relationships among intrinsic religiosity and the mental health variables were fully mediated by emotional support. These findings provide strong support to the notion that the relationship between religiosity and mental health can be reduced to mediators such as social support. Research and theoretical implications are discussed.

PTSD factor structure differences between veterans with and without a PTSD diagnosis.

This study examined differences in posttraumatic stress disorder's (PTSD) factor structure between veterans with and without a PTSD diagnosis. An archival dataset of 378 trauma-exposed Canadian veterans (mostly men) was used. The sample was divided into participants who met DSM-IV criteria for PTSD (n=230) and those who did not (n=148), based on a structured diagnostic interview. Confirmatory factor analysis was conducted to determine which empirically supported four-factor PTSD model best fit the data: (1) King, Leskin, King, and Weathers' (1998) Emotional Numbing model of Reexperiencing, Avoidance, Emotional Numbing and Hyperarousal factors, or (2) Simms, Watson, and Doebbeling's (2002) Dysphoria model of Reexperiencing, Avoidance, Dysphoria, and Hyperarousal factors. Results indicated that both models fit slightly better in the No-PTSD group. A series of measurement invariance tests demonstrated that the two groups varied on all parameters with the exception of factor loadings. The PTSD-group had larger intercepts, factor means, and residual error variance, suggesting that these participants had greater PTSD severity but more measurement error associated with their PTSD ratings. This study contributes to our understanding of how a PTSD diagnosis impacts the structure of PTSD symptoms at the latent level.

Perceived competence and depressive symptoms among adolescents: the moderating role of attributional style.

This longitudinal study examined the interactive effects of depressive attributional style and multiple domains of perceived competence on depressive symptoms among 431 adolescents. Our structural equation modeling with latent factor interactions indicated that (1) for girls with a higher depressive attributional style, lower perceived competence in physical appearance was predictive of depressive symptoms over a 2.5 year period, and (2) regardless of gender, among adolescents with a higher depressive attributional style, lower athletic competence was predictive of higher depressive symptoms 6 months later, which in turn were related to higher depressive symptoms 2 years later. Significant main effects suggested that lower levels of perceived social acceptance were associated with higher subsequent levels of depressive symptoms but only for boys. These findings have implications for understanding the roles of perceived competence and attributional style in predicting depressive symptoms among adolescent girls and boys.

Cognitive-behavioral therapy for anxiety disorders in youth.

Cognitive-behavioral therapies (CBTs) have been shown to be efficacious for the treatment of anxiety disorders in children and adolescents. Randomized clinical trials indicate that approximately two-thirds of children treated with CBT will be free of their primary diagnosis at posttreatment. Although several CBT treatment packages have been investigated in youth with diverse anxiety disorders, common core components have been identified. A comprehensive assessment, development of a good therapeutic relationship and working alliance, cognitive restructuring, repeated exposure with reduction of avoidance behavior, and skills training comprise the core procedures for the treatment of anxiety disorders in youth.

Dispositional optimism, goals, and engagement in health treatment programs.

It has been proposed that dispositional optimism is positively associated with treatment program engagement. However, conflicting evidence exists regarding this relationship. We examined whether the importance of a treatment goal moderates this association. In Study 1 (N = 95), individuals high in optimism were more interested in attending a nutrition education program when the importance of nutrition was first highlighted. In Study 2 (N = 91), participants were given the opportunity to attend psychotherapy to address an academic problem. Dispositional optimism was associated with greater treatment attendance when participants rated their problems as high, relative to low, in importance. It is concluded that the personality variable of dispositional optimism does relate to interest and attendance in treatment, however, treatment goal importance moderates these relationships. It is recommended that practitioners and researchers take an interactionist approach when assessing the role of personality and situational factors in treatment program interest and attendance.

Religious coping, family support, and negative affect in college students.

To understand the influence that religion may have on mental health, the present study examined influences of religious coping and family support on anxiety and depression in 190 college students (women=67.4%; M age=21.7 yr., SD= 4.9). Subjects were recruited as volunteers from undergraduate psychology courses and completed the Ways of Religious Coping Scale, the General Functioning subscale of the Family Assessment Device, the Anxiety Scale of the Personality Assessment Inventory, and the Beck Depression Inventory-Second Edition. Analyses indicated greater family support was significantly associated with less anxiety and depression, whereas religious coping was not significantly correlated with anxiety and depression. Overall findings suggest that family emotional support may provide a stronger source of support for college students than religious coping.

Correlates of separation anxiety symptoms among first-semester college students: an exploratory study.

Separation anxiety disorder (SAD) is rarely considered in college students with anxious symptomatology, but a growing body of evidence suggests that its symptoms are experienced by a significant number of young adults. The authors examined separation anxiety symptoms in a group of first-semester college students living on campus and experiencing extended separation from significant others, generally for the first time. They examined prevalence of separation anxiety symptoms among college students and the relationship between separation anxiety symptoms and students' educational decisions and performance. Results showed that 21% of first-semester college students reported symptoms of separation anxiety. In addition, separation anxiety symptoms were related to childhood SAD, panic attacks, and educational decisions. Results suggest that SAD may be a valid diagnosis in college students and may impact their educational choices and experiences.

Using theatrical presentations as a means of disseminating knowledge of HIV/AIDS risk factors to migrant farmworkers: an evaluation of the effectiveness of the Infórmate program.

Previous research has suggested that Mexican migrant farmworkers are at elevated risk for contracting HIV/AIDS and that they are in need of receiving HIV/AIDS-related education. The present study evaluated the impact of the Infórmate adolescent theater program on HIV/AIDS knowledge and attitudes among farmworker audience members of various ages. Audience members from 7 migrant farmworker camps completed a self-administered questionnaire before and after they observed the Infórmate performance. Paired-samples t-tests and McNemar tests indicated an increase in knowlege in "modes of HIV transmission," "body fluids that can transmit HIV," and items assessing HIV/AIDS "myths." In addition, a greater percentage of farmworkers at posttest reported that they believed that condoms should always be used during sex. The overall findings from this study suggest that theater can be an effective medium for increasing HIV/AIDS-related knowledge among migrant farmworkers. However, it is suggested that, because some farmworkers held false beliefs regarding modes of HIV transmission after viewing the theater program, theater used in combination with other prevention activities may provide for a more comprehensive educational experience.

The influences of cultural values, ethnic identity, and language use on the mental health of Korean American college students.

Little research has examined ethnic identity, cultural values, and native language maintenance as predictors of mental health in Korean Americans. The authors explored the influences of ethnic identity, maintenance of Asian cultural values, and maintenance of Korean language usage on self-esteem, anxiety, and depression in Korean American college students (N = 133). Findings indicated that Korean American men reported relatively high levels of state and trait anxiety and that the overall sample reported a relatively high level of depression. Whereas language and ethnic identity had a minimal influence on the mental health of students, greater cultural value maintenance was associated with decreased self-esteem and increases in state anxiety, trait anxiety, and depression. The positive relationship between cultural values and mental health problems may be indicative of being caught in an ethnic bind, in which the clash of traditional and modern values contributes to psychological distress. The authors discuss clinical implications of the findings.

Evaluating Short-Form Versions of the CES-D for Measuring Depressive Symptoms Among Immigrants From Mexico.

This article examines the feasibility of using a short-form version of the Center for Epidemiologic Studies-Depression Scale (CES-D) in community mental health research with Mexican immigrants. Several features of three published short versions of the CES-D were examined using data combined from seven diverse Mexican immigrant samples from across the United States (N = 685). Results indicate that published short-form versions of the CES-D are reliable, they account for most of the variance in scores from the full CES-D, and there is little evidence that the use of short forms attenuates associations with other concepts relevant to understanding the mental health of Mexican immigrants. Although additional validation research is necessary, the results of this study suggest that short-form versions of the CES-D can be used to study mental health among Mexican immigrants.

The utility of measures of child and adolescent anxiety: a meta-analytic review of the Revised Children's Manifest Anxiety Scale, the State-Trait Anxiety Inventory for Children, and the Child Behavior Checklist.

We evaluated the ability of the Revised Children's Manifest Anxiety Scale (RCMAS), the State-Trait Anxiety Inventory for Children (STAIC), and the Child Behavior Checklist (CBCL) to (a) discriminate between youth with an anxiety disorder and youth without a disorder, (b) discriminate between youth with an anxiety disorder and youth with either externalizing disorders or affective disorders, and (c) measure treatment change. In addition, variables, including age and sex, were explored as possible moderators of instrument utility. A meta-analysis of 43 articles was conducted. A large effect size was found when the instruments were used to compare youth with an anxiety disorder to youth without a disorder. When comparing anxious youth to psychiatric control groups, the picture was mixed; the instruments were found to be useful when discriminating between youth with an anxiety disorder and youth with an externalizing disorder, but not between youth with an anxiety disorder and children and adolescents with an affective disorder. The RCMAS, STAIC, and CBCL were found to be moderately sensitive to treatment gains.