Sensor System Based on a Piezoelectric Resonator with a Lateral Electric Field for Virus Diagnostics.

A sensor system based on a piezoelectric resonator with a lateral electric field in the frequency range 6-7 MHz of the electric field for virus detection is described. Through use of the transmissible virus causing gastroenteritis in pigs and specific antibodies, the possibility of detecting the virus in suspension in real time was determined. It was found that the frequency dependence of the real and imaginary parts of the electrical impedance of such a resonator loaded with a virus suspension changes significantly after the addition of specific antibodies to the suspension. No changes are observed if the antibodies are not specific. Thus, the results obtained illustrate the possibility of detecting viruses in situ, directly in the liquid phase, if the change in the real or imaginary parts of the electrical impedance after the addition of antibodies is used as an analytical signal. The possibility of virus detection in the presence of foreign viral particles has been illustrated.

A new liquid sensor based on a piezoelectric resonator with a radial electric field.

The possibility of development a liquid sensor based on a piezoelectric resonator with radial concentric electrodes is shown. The specified resonator has a large number of resonance peaks corresponding to different vibrational modes. The influence of two types of liquid container with distilled water on the resonance characteristics of these vibrational modes is experimentally investigated. As a result, the optimal type of container and two vibrational modes with frequencies of 0.128 and 0.317 MHz were selected, which retain acceptable Q-factors in the presence of distilled water. The dependences of the resonance frequency and the maximum value of the real part of the electrical impedance of these resonance peaks on the conductivity of the liquid were measured. It has been found that with an increase in the conductivity of the liquid, the resonance frequency of the parallel resonance initially remains practically unchanged, but after reaching a certain value of the conductivity of water, it decreases for both resonances. In this case, the maximum value of the real part of the electrical impedance first decreases, reaches a minimum, and then increases in all cases. It is shown that using these dependences as calibration curves, one can unambiguously determine the conductivity of a liquid in the range of 45-5000 µS/cm.

Evaluation of Elastic Properties and Conductivity of Chitosan Acetate Films in Ammonia and Water Vapors Using Acoustic Resonators.

Novel bio-materials, like chitosan and its derivatives, appeal to finding a new niche in room temperature gas sensors, demonstrating not only a chemoresistive response, but also changes in mechanical impedance due to vapor adsorption. We determined the coefficients of elasticity and viscosity of chitosan acetate films in air, ammonia, and water vapors by acoustic spectroscopy. The measurements were carried out while using a resonator with a longitudinal electric field at the different concentrations of ammonia (100-1600 ppm) and air humidity (20-60%). It was established that, in the presence of ammonia, the longitudinal and shear elastic modules significantly decreased, whereas, in water vapor, they changed slightly. At that, the viscosity of the films increased greatly upon exposure to both vapors. We found that the film's conductivity increased by two and one orders of magnitude, respectively, in ammonia and water vapors. The effect of analyzed vapors on the resonance properties of a piezoelectric resonator with a lateral electric field that was loaded by a chitosan film on its free side was also experimentally studied. In these vapors, the parallel resonance frequency and maximum value of the real part of the electrical impedance decreased, especially in ammonia. The results of a theoretical analysis of the resonance properties of such a sensor in the presence of vapors turned out to be in a good agreement with the experimental data. It has been also found that with a growth in the concentration of the studied vapors, a decrease in the elastic constants, and an increase in the viscosity factor and conductivity lead to reducing the parallel resonance frequency and the maximum value of the real part of the electric impedance of the piezoelectric resonator with a lateral electric field that was loaded with a chitosan film. This leads to an increase in the sensitivity of such a sensor during exposure to these gas vapors.