1.
Angew Chem Int Ed Engl
; 55(33): 9728-32, 2016 08 08.
Article
in English
| MEDLINE
| ID: mdl-27346363
ABSTRACT
Copper-catalyzed enantioselective propargylation of indoles with propargylic esters and sequential Huisgen cycloaddition with azides lead to the construction of chiral triarylmethanes, bearing a quaternary carbon center, with high to excellent enantioselectivities. The result described herein can be used in the enantioselective preparation of a tetraarylmethane.
2.
Angew Chem Int Ed Engl
; 54(13): 4060-4, 2015 Mar 23.
Article
in English
| MEDLINE
| ID: mdl-25651803
ABSTRACT
The diastereo- and enantioselective propargylic alkylation of propargylic alcohols with E-enecarbamates in the presence of a catalytic amount of thiolate-bridged diruthenium complexes bearing an optically active phosphoramide moiety gives the corresponding propargylic alkylated products (up to 97 % ee).