Subject(s)

Bone Morphogenetic Proteins/deficiency , Growth Differentiation Factors/deficiency , Recombinant Fusion Proteins/pharmacology , beta-Thalassemia/metabolism , Anemia/blood , Anemia/drug therapy , Anemia/etiology , Animals , Biomarkers , Bone Morphogenetic Proteins/genetics , Bone Morphogenetic Proteins/metabolism , Disease Models, Animal , Growth Differentiation Factors/genetics , Growth Differentiation Factors/metabolism , Mice , Mice, Transgenic , Treatment Outcome , beta-Thalassemia/blood , beta-Thalassemia/drug therapy , beta-Thalassemia/genetics