ABSTRACT
We report a clinical case of cerebral actinomycotic granuloma that was preoperatively diagnosed as an intracerebral tumor. On the basis of a histological examination performed after lesion resection, the diagnosis of a cerebral actinomycotic granuloma was made. The article presents long-term outcomes of the surgery. The literature data on cases of various forms of cerebral actinomycosis are provided.
Subject(s)
Actinomycosis/surgery , Brain Neoplasms/surgery , Granuloma/surgery , Actinomycosis/diagnosis , Brain Neoplasms/diagnosis , Diagnosis, Differential , Granuloma/diagnosis , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Treatment Outcome , Xanthomatosis/diagnosis , Xanthomatosis/surgerySubject(s)
Contusions/pathology , Contusions/radiotherapy , Laser Therapy , Spinal Cord Injuries/pathology , Spinal Cord Injuries/radiotherapy , Animals , Disease Models, Animal , Humans , Nerve Regeneration/radiation effects , Rabbits , Spinal Cord/pathology , Spinal Cord/radiation effects , Time FactorsABSTRACT
Three stages of cerebral metabolism differing in tension were revealed in the acute period of closed craniocerebral trauma. In the mobilization stage (1 hour after trauma) enzymatic reactions reflecting the activity of aerobic and anaerobic glycolysis are sharply intensified. In the resistance stage (from 3 hours to 2 weeks after trauma) stable conversion to anaerobic glycolysis is noted, which leads to marked deficiency in macroergic compounds. Activation of alpha-glycerophosphate, pentose shunt by means of pharmacological agents in combination with hypothermia may be recommended in this stage. In the restoration stage (more than 2 weeks after the trauma) the metabolic processes are gradually normalized and therapy need not be so intensive.
