Subject(s)
Anti-Bacterial Agents/therapeutic use , Anticoagulants/therapeutic use , Behcet Syndrome/diagnostic imaging , Pulmonary Embolism/diagnostic imaging , Superior Vena Cava Syndrome/diagnostic imaging , Thrombosis/diagnostic imaging , Behcet Syndrome/drug therapy , Behcet Syndrome/physiopathology , Colchicine/analogs & derivatives , Colchicine/therapeutic use , Diagnostic Imaging , Humans , Male , Prednisolone/therapeutic use , Pulmonary Embolism/drug therapy , Pulmonary Embolism/physiopathology , Superior Vena Cava Syndrome/drug therapy , Superior Vena Cava Syndrome/physiopathology , Thrombosis/drug therapy , Thrombosis/physiopathology , Treatment Outcome , Tubulin Modulators/therapeutic use , Warfarin/therapeutic use , Young AdultSubject(s)
Humans , Male , Young Adult , Pulmonary Embolism/diagnostic imaging , Thrombosis/diagnostic imaging , Superior Vena Cava Syndrome/diagnostic imaging , Behcet Syndrome/diagnostic imaging , Anti-Bacterial Agents/therapeutic use , Anticoagulants/therapeutic use , Pulmonary Embolism/physiopathology , Pulmonary Embolism/drug therapy , Thrombosis/physiopathology , Thrombosis/drug therapy , Warfarin/therapeutic use , Superior Vena Cava Syndrome/physiopathology , Superior Vena Cava Syndrome/drug therapy , Prednisolone/therapeutic use , Diagnostic Imaging , Colchicine/analogs & derivatives , Colchicine/therapeutic use , Behcet Syndrome/physiopathology , Behcet Syndrome/drug therapy , Treatment Outcome , Tubulin Modulators/therapeutic useABSTRACT
An adolescent with a recent diagnostic of Behçet's Disease (BD) was admitted with fever and intracardiac lesions detected on a routine transthoracic echocardiography, suggestive of endocarditis. Due to the absence of improvement after several rounds of antibiotics the patient was submitted to contrast-enhanced cardiac MRI that showed signs of intracardiac thrombosis, superior vena cava syndrome and pulmonary thromboembolism. The patient underwent surgery to excise the lesions and has been treated with cyclophosphamide and high dose prednisolone achieving complete remission. Intracardiac thrombosis is a rare manifestation of BD, and is associated with a poor prognosis. These patients usually require a combination of anticoagulation and immunosuppression to achieve remission.
