Subject(s)
Adrenal Insufficiency/diagnosis , Autonomic Nervous System Diseases/diagnosis , Esophageal Achalasia/diagnosis , Adrenal Insufficiency/genetics , Adrenal Insufficiency/physiopathology , Autonomic Nervous System Diseases/genetics , Autonomic Nervous System Diseases/physiopathology , Child , Child, Preschool , Esophageal Achalasia/genetics , Esophageal Achalasia/physiopathology , Female , Humans , Hypotension, Orthostatic , Infant , Intelligence , Syndrome , Tears/metabolismABSTRACT
We report the clinical course of a 6-month-old girl with recurrent infection of the left lung, persistent wheezing, and a suspected congenital heart anomaly (patent ductus arteriosus. Chest radiography revealed hyperinflation and slight inflammation of the left lung. Tracheobronchoscopy and left-sided bronchography showed a collapsed segment of the left main bronchus, 3 cm long. Computed tomography confirmed hyperinflation of the left lung and atelectasis of the superior lobe. There were no signs of extramural compression. Color-flow Doppler echocardiography confirmed the suspicion of patent ductus arteriosus. To the best of our knowledge, there is no other report in the literature of a patient with this combination of anomalies. After receiving 2 weeks of antibiotic treatment, the patient underwent surgical repair The patent ductus arteriosus was closed by means of a triple-ligature procedure, and during the same operation a bronchopexy was performed, securing the left main bronchus to the closed ductus tissue by means of sutures. There have been no complications in the postoperative period. Clinical follow-up, as well as echocardiography and bronchoscopy, have yielded normal results 14 months after surgery.