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J Cutan Pathol ; 48(1): 86-89, 2021 Jan.
Article in English | MEDLINE | ID: mdl-32640078

ABSTRACT

Clear-cell carcinoma (CCC) is an uncommon malignant tumor of minor salivary glands. It characteristically has a low-grade morphology and a favorable outcome by most reports. An EWSR1-ATF1 fusion can be detected in the majority of cases. We present a rare case of CCC, which had an aggressive course with the development of cutaneous metastases. Practicing dermatopathologists should be aware of this tumor given its low-grade appearance and histopathologic resemblance to other primary cutaneous adnexal and metastatic neoplasms.


Subject(s)
Adenocarcinoma, Clear Cell/secondary , Head and Neck Neoplasms/secondary , Salivary Gland Neoplasms/pathology , Skin Neoplasms/secondary , Adenocarcinoma, Clear Cell/genetics , Adult , Female , Head and Neck Neoplasms/genetics , Humans , Oncogene Proteins, Fusion , Pregnancy , Pregnancy Complications, Neoplastic/genetics , Pregnancy Complications, Neoplastic/pathology , Salivary Gland Neoplasms/genetics , Salivary Glands, Minor/pathology , Scalp/pathology , Skin Neoplasms/genetics
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