Subject(s)
Hepatomegaly/etiology , Hyperpigmentation/etiology , Leishmaniasis/diagnosis , Splenomegaly/etiology , Amphotericin B/therapeutic use , Bone Marrow Examination , Child , Diagnosis, Differential , Female , Humans , Leishmania , Leishmaniasis/complications , Leishmaniasis/drug therapy , Neglected Diseases/diagnosisABSTRACT
Amitraz is an acaricide and insecticide used to treat ticks, which infest domestic animals in developing countries. Because of its widespread use, it is one of the common poisons unintentionally consumed by infants and children when left unsupervised. A 3-year-old boy was brought with unintentional consumption of Amitraz. On examination, he was found to be progressively drowsy, with an irregular pulse, bradycardia, and hypotension. He was treated with atropine, intravenous fluids, and dopamine infusion; hemodynamic stability was achieved within 36 hours after ingestion. Amitraz is an unusual but deadly poison unintentionally consumed by children. It can be suspected in the setting of rural households in developing countries having pets. There is no antidote available, and treatment is mainly supportive.
Subject(s)
Adrenergic alpha-2 Receptor Agonists/poisoning , Pesticides/poisoning , Toluidines/poisoning , Adrenergic alpha-2 Receptor Agonists/pharmacology , Blood Pressure/drug effects , Central Nervous System/drug effects , Child, Preschool , Fluid Therapy , Glycosuria/chemically induced , Heart Rate/drug effects , Humans , Male , Pesticides/pharmacology , Polyuria/chemically induced , Toluidines/pharmacologyABSTRACT
Hodgkin's Lymphoma is one of the commonly encountered lymphomas in childhood. Most of the children present with lymphadenopathy. A rare subset of children do present with constellation of atypical symptoms as paraneoplastic syndromes. We hereby present an 11-year-old boy with classical Hodgkin's Lymphoma associated with Alopecia areata and demyelination as paraneoplastic manifestations. Both these paraneoplastic manifestations improved after initiating chemotherapy (ABVD regimen). A high index of suspicion for underlying malignancy would help clinicians in clinching an early diagnosis and would avert the associated complications.