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MMWR Morb Mortal Wkly Rep ; 73(12): 271-276, 2024 Mar 28.
Article in English | MEDLINE | ID: mdl-38547037

ABSTRACT

In September 2023, CDC's Advisory Committee on Immunization Practices recommended updated 2023-2024 (monovalent XBB.1.5) COVID-19 vaccination for all persons aged ≥6 months to prevent COVID-19, including severe disease. As with past COVID-19 vaccines, additional doses may be considered for persons with immunocompromising conditions, who are at higher risk for severe COVID-19 and might have decreased response to vaccination. In this analysis, vaccine effectiveness (VE) of an updated COVID-19 vaccine dose against COVID-19-associated hospitalization was evaluated during September 2023-February 2024 using data from the VISION VE network. Among adults aged ≥18 years with immunocompromising conditions, VE against COVID-19-associated hospitalization was 38% in the 7-59 days after receipt of an updated vaccine dose and 34% in the 60-119 days after receipt of an updated dose. Few persons (18%) in this high-risk study population had received updated COVID-19 vaccine. All persons aged ≥6 months should receive updated 2023-2024 COVID-19 vaccination; persons with immunocompromising conditions may get additional updated COVID-19 vaccine doses ≥2 months after the last recommended COVID-19 vaccine.


Subject(s)
COVID-19 , Influenza Vaccines , Influenza, Human , Adult , United States/epidemiology , Humans , Adolescent , Influenza, Human/epidemiology , COVID-19 Vaccines , COVID-19/epidemiology , COVID-19/prevention & control , Vaccination , Hospitalization
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