ABSTRACT
1. The effect of intravenously injected zinc (Zn) on tissue Zn concentrations and pancreas metallothionein (MT) gene expression in broilers was investigated to detect differences in the tissue utilisation of Zn from different Zn sources. 2. A total of 432 male chickens were randomly allotted on d 22 post-hatch to one of nine treatments in a completely randomised design. Chickens were injected with either a 0.9% (w/v) NaCl solution (control) or a saline solution supplemented with Zn sulphate or one of three organic Zn chelates with weak (Zn-AA W), moderate (Zn-Pro M) or strong (Zn-Pro S) chelation strengths at two injected Zn dosages calculated according to two Zn absorbability levels (6 and 12%). 3. Bone and pancreas Zn concentrations, pancreas MT mRNA levels and MT concentrations increased on d 6 and 12 after Zn injections as the injected Zn dosages increased. Chickens injected with the Zn-Pro S had lower bone Zn concentration than those injected with the Zn-Pro M or Zn-AA W on d 6 after injections. However, no differences among Zn sources were observed in bone Zn concentration on d 12 after injections, pancreas Zn concentrations, pancreas MT mRNA levels and MT concentrations on both d 6 and d 12 after injections. 4. It was concluded that the injected Zn-Pro S was the least favourable for bone Zn utilisation of broilers. The pancreas Zn concentration and pancreas MT gene expressions might not be sensitive enough to detect differences in the tissue utilisation of injected Zn in broilers between organic and inorganic Zn sources or among organic Zn sources.
Subject(s)
Chickens/metabolism , Gene Expression/drug effects , Metallothionein/genetics , Zinc/administration & dosage , Zinc/analysis , Animals , Bone and Bones/chemistry , Injections, Intravenous/veterinary , Male , Metallothionein/analysis , Pancreas/chemistry , RNA, Messenger/analysis , Random AllocationABSTRACT
The UASB reactor was applied for biodegradation of organic compounds in coking wastewater. The influent pH ranged between 6.8 and 7.2, and stirring speed and temperature were controlled at 2 r/min and 30±1°C, respectively. The reactor was successfully started up in 133 days. When the influent COD was 2,600 mg/L (VLR was 2.6 kg/m(3) d), the removal rate of COD was about 54% and the effluent VFA was below 400 mg/L. GC/MS analysis indicated that the coking wastewater mainly contained aniline, phenol, o-phenol, p-cresol, benzoic acid, indole, quinoline etc. Twenty four kinds of organic compounds were detected in the influent, and 20 kinds of organic compounds were completely removed in the UASB reactor. The biodegradation of organic compounds followed Grau second-order kinetics. It was proved to be an effective and feasible method for coking wastewater anaerobic treatment.
Subject(s)
Bioreactors , Coal , Organic Chemicals/analysis , Sewage , Water Pollutants, Chemical/analysis , Water Purification/methods , Anaerobiosis , Biodegradation, Environmental , Bioreactors/microbiology , Gas Chromatography-Mass Spectrometry , Kinetics , Microscopy, Electron, Scanning , Sewage/chemistry , Sewage/microbiology , Surface Properties , Water Purification/instrumentationABSTRACT
Experimental and clinical researches were done for the purpose of that to treat the hyperlipemia with Dahuang Zhechong Wan (DHZCW). The patients of primary hyperlipemia were divided into two groups. One group was treated with DHZCW, the other with inositol nicotinate as control. DHZCW could reduce the serum total cholesterol (0.05 less than P less than 0.2), triglyceride (P less than 0.05), the blood viscosity (P less than 0.01), reductive viscosity (P less than 0.001) and fibrinogen (0.05 less than P less than 0.2). No significant change of the other item of hemorheology, HDL-c and the subfraction were observed. No significant differential effect between those two groups. The experimental hyperlipidemic model was made by feeding cholesterol and axungia on rabbits. The results showed that DHZCW could reduce the serum total cholesterol (P less than 0.05), triglyceride (P less than 0.05), beta-LP (P less than 0.01), the blood viscosity (P less than 0.05) and plasma viscosity (P less than 0.05), but no significant effect on HDL-c and its subfraction, ESR, index of erythrocytic deformation and hematocrit. DHZCW could change the viscosity of blood of hyperlipemia and reduce the total cholesterol, triglyceride and fibrinogen of the blood. It might have some beneficial effects on atherosclerosis and prevent ischemic cardiovascular and cerebrovascular diseases.
Subject(s)
Drugs, Chinese Herbal/therapeutic use , Hyperlipidemias/drug therapy , Adult , Aged , Animals , Blood Viscosity/drug effects , Cholesterol, HDL/blood , Female , Humans , Hyperlipidemias/blood , Male , Middle Aged , RabbitsABSTRACT
Twenty rabbits with experimental hyperlipoproteinemia were divided randomly into two groups. The first group was administered Laminaria digitata powder (1 g daily) for 14 days. Another was given only the routine menu. It was found that the Laminaria digitata had a significant effect of lowering total cholesterol, -lipoprotein, especially triglyceride (P less than 0.01), meanwhile it could increase the level of HDL-c and HDL2-c. Also it could reduce relative blood viscosity, relative plasma viscosity, reductive viscosity and fibrinogen very significantly (P less than 0.01). However HDL3-c, hematocrit and index of erythrocytic deformability were not much influenced (P greater than 0.05). This experiment showed that there was a connection between the blood lipids and the concept of "Phlegm" in TCM.
