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1.
A new class of mRNA drugs targets poison exons.
Sheridan, Cormac.
Nat Biotechnol ; 42(8): 1159-1161, 2024 Aug.
Article in English | MEDLINE | ID: mdl-39143167

Subject(s)
Exons , RNA, Messenger , Humans , Exons/genetics , RNA, Messenger/genetics
2.
B cells as drug factories.
Sheridan, Cormac.
Nat Biotechnol ; 42(6): 823-826, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38886605
3.
A second chance for plant biotechnology in Europe.
Sheridan, Cormac.
Nat Biotechnol ; 42(5): 687-689, 2024 May.
Article in English | MEDLINE | ID: mdl-38760561

Subject(s)
Biotechnology , Europe , Plants, Genetically Modified , Crops, Agricultural/genetics , Plants/genetics
4.
Innovators want pills to treat sickle cell disease. Can they match gene therapy?
Sheridan, Cormac.
Nat Biotechnol ; 42(3): 347-350, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38491281

Subject(s)
Anemia, Sickle Cell , Humans , Anemia, Sickle Cell/drug therapy , Anemia, Sickle Cell/genetics , Genetic Therapy
5.
Can single-cell biology realize the promise of precision medicine?
Sheridan, Cormac.
Nat Biotechnol ; 42(2): 159-162, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38361071
6.
The world's first CRISPR therapy is approved: who will receive it?
Sheridan, Cormac.
Nat Biotechnol ; 42(1): 3-4, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37989785
7.
Can gene editing drive out HIV and hepatitis viruses from inside cells?
Sheridan, Cormac.
Nat Biotechnol ; 41(11): 1491-1493, 2023 Nov.
Article in English | MEDLINE | ID: mdl-37903922
8.
Drugs catch a ride through the blood-brain barrier.
Sheridan, Cormac.
Nat Biotechnol ; 41(9): 1182-1184, 2023 09.
Article in English | MEDLINE | ID: mdl-37699989

Subject(s)
Blood-Brain Barrier , Drug Delivery Systems
9.
Unprecedented blood biomarker enables ALS drug approval.
Sheridan, Cormac.
Nat Biotechnol ; 41(7): 886-888, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37386297

Subject(s)
Amyotrophic Lateral Sclerosis , Humans , Amyotrophic Lateral Sclerosis/diagnosis , Amyotrophic Lateral Sclerosis/drug therapy , Drug Approval , Biomarkers
10.
Why gene therapies must go virus-free.
Sheridan, Cormac.
Nat Biotechnol ; 41(6): 737-739, 2023 Jun.
Article in English | MEDLINE | ID: mdl-37316735
11.
Genetic medicines aim straight for the heart.
Sheridan, Cormac.
Nat Biotechnol ; 41(4): 435-437, 2023 04.
Article in English | MEDLINE | ID: mdl-37016163

Subject(s)
Genetic Therapy , Heart
12.
Shoot the messenger: RNA editing is here.
Sheridan, Cormac.
Nat Biotechnol ; 41(3): 306-308, 2023 03.
Article in English | MEDLINE | ID: mdl-36879010

Subject(s)
Proteins , RNA Editing , RNA Editing/genetics , Proteins/genetics , Base Sequence , RNA
13.
Industry appetite for natural killer cells intensifies.
Sheridan, Cormac.
Nat Biotechnol ; 41(2): 159-161, 2023 02.
Article in English | MEDLINE | ID: mdl-36792706

Subject(s)
Appetite , Killer Cells, Natural , Cytotoxicity, Immunologic
14.
For hemophilia and thalassemia, a new era of 'one-and-done' gene therapies has arrived.
Sheridan, Cormac.
Nat Biotechnol ; 40(11): 1531-1533, 2022 11.
Article in English | MEDLINE | ID: mdl-36347983

Subject(s)
Hemophilia A , Medicine , Thalassemia , Humans , Hemophilia A/genetics , Hemophilia A/therapy , Thalassemia/genetics , Thalassemia/therapy
15.
Repairing the eye.
Sheridan, Cormac.
Nat Biotechnol ; 40(10): 1419-1421, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36207591
16.
mRNA printers kick-start personalized medicines for all.
Sheridan, Cormac.
Nat Biotechnol ; 40(8): 1160-1162, 2022 08.
Article in English | MEDLINE | ID: mdl-35945442

Subject(s)
RNA, Messenger , Biomechanical Phenomena
17.
RNA drugs lower lipoprotein(a) and genetically driven cholesterol.
Sheridan, Cormac.
Nat Biotechnol ; 40(7): 983-985, 2022 07.
Article in English | MEDLINE | ID: mdl-35831664

Subject(s)
Lipoprotein(a) , RNA , Cholesterol/genetics , Cholesterol, HDL/genetics , Cholesterol, LDL/genetics , Lipoprotein(a)/genetics
18.
Topical herpesvirus gene therapy enters final lap.
Sheridan, Cormac.
Nat Biotechnol ; 40(6): 809-811, 2022 06.
Article in English | MEDLINE | ID: mdl-35705715

Subject(s)
Genetic Therapy
19.
COVID-19 vaccine makers chase variant-ready vaccines.
Sheridan, Cormac.
Nat Biotechnol ; 40(2): 141-143, 2022 02.
Article in English | MEDLINE | ID: mdl-35046613

Subject(s)
COVID-19 Vaccines , COVID-19 , SARS-CoV-2 , Vaccine Development , COVID-19/prevention & control , COVID-19/virology , Humans
20.
Publisher Correction: Sickle cell gene therapies approach watershed.
Sheridan, Cormac.
Nat Biotechnol ; 40(1): 131, 2022 Jan.
Article in English | MEDLINE | ID: mdl-34961775
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