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1.
J Pharm Bioallied Sci ; 16(Suppl 2): S1461-S1464, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38882801

ABSTRACT

Oral submucous fibrosis (OSF) is a chronic disorder prevalent in South and Southeast Asia and is mainly related to the habit of chewing betel quid. Although there are numerous South-Asian studies about OSF, there is no study that evaluates the awareness of OSF among expatriate populations of South-Asian origin. Evaluated the awareness of OSF among South-Asian expatriate patients reporting to a dental hospital in Sharjah. Prevalidated questionnaires were given to 150 expatriate patients of South-Asian origin with quid-chewing habit reporting to the teaching clinics of a dental hospital in the United Arab Emirates. Among the 150 patients, 103 responded to the questionnaire. Among the 103 respondents, 11.65% were aware of OSF. Respondents living in shared residency and labor camps had significantly (P = 0.43) lower awareness of OSF compared to respondents living with their families. The results of our study show that the awareness of OSF is lower among the respondents living in labor camps and shared residencies. The younger respondents had more awareness of OSMF and were more likely to quit the quid-chewing habit.

2.
Int J Dent Hyg ; 2022 Dec 30.
Article in English | MEDLINE | ID: mdl-36583292

ABSTRACT

OBJECTIVE: This multi-arm, randomized, double-blinded, controlled clinical trial was designed to evaluate the clinical efficacy of 0.5% green tea (GT), 0.2% chlorhexidine (CHX) and aloe vera (AV) mouthwash as compared to the control (CNT) group (scaling and polishing alone with no mouthwash) in the management of dental biofilm induced gingivitis among 18-40-year-old patients. MATERIAL AND METHODS: Sixty patients with generalized dental biofilm-induced gingivitis were randomly allocated to four study groups (n = 15 each) for treatment, namely Group GT, Group CHX, Group AV and Group CNT after scaling and polishing were administered to all the patients. Plaque index (PI), gingival index (GI) and sulcular bleeding index (SBI) were recorded at baseline, 14th and 21st day. RESULTS: PI, GI and SBI at various time intervals (baseline, 14th and 21st day) showed high statistically significant differences within the group (p < 0.01). Among these, the maximum percentage change was found in the CHX group followed by GT when evaluated from baseline to 21st day. The least percentage change was found in the AV group for PI and GI while the CNT group showed the least percentage change for sulcular index when evaluated from 14th to 21st day. Inter-group results showed high statistically significant differences (p < 0.01) for PI and GI when evaluated between baseline to 14th day and baseline to 21st day. SBI also showed statistically significant differences (p < 0.05) when evaluated between baselines to 14th day and baseline to 21st day. CONCLUSION: Green tea mouthwash displayed a significant reduction in plaque index, gingival index and sulcular bleeding index. 0.5% green tea catechin has equivalent anti-plaque efficacy as 0.2% chlorhexidine gluconate and can be considered a potent alternative to prevent and treat gingival diseases.

3.
J Pharm Bioallied Sci ; 12(Suppl 1): S589-S594, 2020 Aug.
Article in English | MEDLINE | ID: mdl-33149526

ABSTRACT

BACKGROUND: The accumulation and maturation of bacterial plaque at the gingival margin is widely recognized as the primary etiological factor in the development of chronic periodontitis. With the rise in bacterial resistance to antibiotics, there is considerable interest in the development of other classes of antimicrobials for the control of infection. AIM: The aim of this study was to evaluate the efficacy of Psidium guajava (guava) and Allium sativum (garlic) on Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. MATERIALS AND METHODS: Aqueous guava extract (AGvE), ethanolic guava extract (EGvE), aqueous garlic extract (AGE), and ethanolic garlic extract (EGE) were prepared. The inhibitory effects of these extracts for the periodontal pathogens were tested by agar well diffusion method. Minimal inhibitory concentration (MIC) of the aqueous and ethanol extracts of guava and garlic was determined by macrobroth dilution method. Minimum bactericidal concentration (MBC) was done to observe the bactericidal effect of the guava and garlic extracts against the organisms. RESULTS: Of the AGE, 25, 50, and 75 µL showed 16, 20, and 25 mm zone of inhibition, respectively, on P. gingivalis. The AGE showed greater bacteriostatic activity against the P. gingivalis with MIC determined at 16.6 µL/mL. MIC determined for AGvE and EGvE was at 75 µL/mL concentration for P. gingivalis, whereas EGvE showed the activity at 75 µL/mL on P. gingivalis. MIC determined for AGvE was at 50 µL/mL, whereas MIC determined for EGvE was at 3.12 µL/mL for A. actinomycetemcomitans. CONCLUSION: P. guajava and A. sativum displayed a significant antibacterial effect. A. sativum was found to be most effective against P. gingivalis, whereas P. guajava showed the highest efficacy on A. actinomycetemcomitans.

4.
J Pharm Bioallied Sci ; 11(Suppl 2): S97-S106, 2019 May.
Article in English | MEDLINE | ID: mdl-31198320

ABSTRACT

AIM: The aim of this review was to analyze the data in the available literature regarding aspects of periodontally accelerated orthodontic therapy such as reduction in treatment time, variation in surgical techniques, and patient satisfaction. MATERIALS AND METHODS: An internet-based search was performed for the articles published between January 2008 and August 2018 using keywords periodontal accelerated orthodontic tooth movement, corticotomy, bone grafting, tooth movement, and treatment duration. A total of 84 articles were obtained from MEDLINE and Embase search engines, of which 31 articles were eligible to be included for the systematic review. RESULTS: On analysis, it was observed that the earlier studies were predominantly pertaining to case reports. In the later part of the decade considered in this review, it was observed that the emphasis was given to clinical and animal studies. CONCLUSIONS: Most of the studies included in the review concluded that there was a significant reduction in orthodontic treatment duration using periodontal accelerated techniques compared to conventional orthodontic treatment.

6.
J Clin Exp Dent ; 6(4): e335-8, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25593652

ABSTRACT

OBJECTIVES: Diabetes Mellitus is emerging as a major health problem over these years. Present method of blood glucose monitoring by venepuncture is invasive leading to reduced patient compliance and thereby ineffective judicious monitoring. The need of the hour is to direct research in the direction of establishing painless and more acceptable blood glucose analysis method.The objective of the study is to conduct a comparative analysis of the concentrations of salivary glucose and blood glucose in type 2 diabetes mellitus patients. STUDY DESIGN: This study assessed glucose levels using the glucose oxidase method in blood and unstimulated saliva in 90 subjects who were divided into 3 equal groups of controlled type 2 diabetes, uncontrolled type 2 diabetes and those without diabetes. Statistical analysis was carried out using one way ANOVA, Post hoc Tukeys tests and Pearson's correlation coefficient test. RESULTS: Salivary glucose levels were significantly higher in patients with diabetes than controls. There was a significant positive correlation between salivary and plasma glucose levels in patients with diabetes. CONCLUSIONS: Glucose concentration in saliva is higher in diabetics but hyperglycemia does not influence salivary glucose levels. Further clarification is required to claim the diagnostic potentials of saliva in diabetes. Key words:Salivary glucose, type 2 diabetes mellitus, blood glucose.

7.
South Asian J Cancer ; 2(2): 54, 2013 Apr.
Article in English | MEDLINE | ID: mdl-24455549

ABSTRACT

Trichoepitelioma is an extremely rare cosmetically disfiguring condition usually affecting the females. Trichoepitheliomas are benign lesions seen on the face, which are thought to derive from the hair follicle. Malignant transformation to basal cell carcinoma is rare and occurs late in the course of the disease These lesions are often misinterpreted and diagnosed clinically as neurofibromatosis or histpathologically as basal cell carcinoma. We report a case of multiple trichoepithelioma occurring in a male patient. The patient presented with multiple dermatologic growths on the face with varied histopathological presentations which have been described in detail.

8.
South Asian J Cancer ; 2(3): 142-4, 2013 Jul.
Article in English | MEDLINE | ID: mdl-24455594

ABSTRACT

BACKGROUND: Quid chewing practice has been a part of our tradition since centuries with little known evidence of oral cancer. However, recent trends show a rise in occurrence of oral cancer often associated with tobacco and arecanut usage. Ascorbic acid is an important salivary antioxidant. Betel leaf which is used in quid is known to contain ascorbic acid. AIM: The aim of our study was to assess the salivary levels of ascorbic acid in traditional quid chewers so as to determine whether the betel leaf has protective antioxidant action. MATERIALS AND METHODS: Salivary ascorbic acid levels of 60 subjects were estimated using the Dinitrophenyl hydrazine method. RESULTS: The results revealed that quid chewers who used betel leaf had higher salivary ascorbic acid content compared to nonbetel leaf quid chewers. This could possibly be due to the protective antioxidants in the betel leaf.

9.
J Oral Sci ; 53(1): 133-6, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21467827

ABSTRACT

Acromegaly is an acquired disorder related to excessive production of growth hormone after epiphyseal closure of bones. It is characterized by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The prevalence is estimated at 1:140,000-250,000. Although acromegaly rarely manifests in the orofacial regions, it must be considered in patients who develop malocclusion after adolescence. Here, we present a case of acromegaly with brief review of the literature.


Subject(s)
Acromegaly/complications , Anodontia/complications , Chronic Periodontitis/complications , Hypercementosis/complications , Macroglossia/complications , Cephalometry , Female , Humans , Malocclusion/complications , Middle Aged , Prognathism/complications
10.
J Oral Sci ; 52(2): 343-6, 2010 Jun.
Article in English | MEDLINE | ID: mdl-20587964

ABSTRACT

Non-steroidal anti-inflammatory drugs are commonly prescribed in dental practice after minor oral surgical procedures such as tooth extraction. Diclofenac sodium is one of the non-steroidal anti-inflammatory drugs widely used for pain relief in dentistry. Although adverse reactions to these drugs are rare, at times they can cause a life-threatening phenomenon. Stevens-Johnson syndrome is one such potentially lethal adverse drug reaction. Most reported cases of analgesic-induced Stevens-Johnson syndrome were due to oxicams or propionic acid derivatives. There are very few detailed reports of Stevens-Johnson syndrome due to use of diclofenac. We report here a case of Stevens-Johnson syndrome which occurred due to use of diclofenac sodium. The clinical features of this condition and multidisciplinary management of the patient are described in brief.


Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Diclofenac/adverse effects , Stevens-Johnson Syndrome/chemically induced , Conjunctival Diseases/chemically induced , Dental Caries/therapy , Female , Follow-Up Studies , Humans , Leg Ulcer/chemically induced , Middle Aged , Oral Ulcer/chemically induced , Pain, Postoperative/drug therapy , Skin Ulcer/chemically induced , Tooth Extraction , Ulcer/chemically induced
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