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Vestn Ross Akad Med Nauk ; (12): 31-6, 2006.
Article in Russian | MEDLINE | ID: mdl-17784570

ABSTRACT

The revascularizing properties of the greater omentum used as a vascular pedicle for the prefabrication of skin, skin/cartilage or skin/ bone autografts, and their viability after rotation and recipient zone infection were studied in rat experiments. The experiment showed that complexity factor did not have a significant effect on the revascularizing properties of the greater omentum, and required only an insignificant prolongation of prefabrication period. Skin/omental, skin/cartilageous, and skin/bony autografts based on the greater omentum formed by day 7, 14, and 21, respectively. After these periods prefabricated autografts remained viable upon rotation. In case of infection, the survival rate of prefabricated skin/bone autografts, revascularized with two-layer greater omentum, is lower than that of skin/cartilage ones. The technique of prefabrication of autografts including skin, cartilage, and bone, is a promising method for closure of vast multicomponent defects in complicated clinical situations.


Subject(s)
Bone Transplantation/methods , Cartilage, Articular/transplantation , Omentum/transplantation , Skin Transplantation/methods , Surgical Flaps/blood supply , Wound Healing/physiology , Animals , Disease Models, Animal , Male , Omentum/blood supply , Rats , Rats, Wistar , Transplantation, Autologous
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