ABSTRACT
Purposeâ :â Postoperative pancreatic fistula (POPF) is a serious complication after gastrectomy for gastric cancer. The purpose of this study is to identify the risk factor of POPF and evaluate C-reactive protein on postoperative day 1 (POD1) as the predictor for POPF after laparoscopic gastrectomy (LG). Methodsâ :â Between May 2013 and September 2016, 226 patients who underwent LG for gastric cancer were investigated. Patients were divided into 2 groups; POPF group (nâ =â 17) and control group (nâ =â 209). Clinicopathological factors were compared between 2 groups. Resultsâ :â In POPF group, there are more male patients (pâ =â 0.003) compared with control group. Preoperative factors, such as age, BMI, and prevalence of previous operation and comorbidity showed no significant difference between 2 groups. Regarding tumor factors and perioperative data such as blood loss and operative time, there were also no significant difference between 2 groups. POPF group showed longer postoperative hospital stay, and higher serum CRP level on POD1 (pâ <â 0.0001). Multivariate analysis revealed that high CRP level on POD1 (â ≥â 3mg/dl) was independent risk factor of POPF. Conclusionsâ :â High serum CRP level on POD1 can predict the occurrence of POPF. J. Med. Invest. 66 : 285-288, August, 2019.