1.
Thorax
; 63(10): 933-4, 2008 Oct.
Article
in English
| MEDLINE
| ID: mdl-18820120
ABSTRACT
Pulmonary veno-occlusive disease (PVOD) is a disorder which causes progressive pulmonary hypertension, usually presenting with worsening dyspnoea and right heart failure. Pulmonary oedema induced by pulmonary vasodilator therapy to reduce pulmonary arterial pressure has been well described in PVOD, but here we describe a case of PVOD presenting with recurrent episodes of acute non-cardiogenic pulmonary oedema, in the absence of significant pulmonary hypertension. Concern over the risk of precipitating pulmonary oedema led us to use inhaled nitric oxide to predict the safety and efficacy of sildenafil.
Subject(s)
Bronchodilator Agents/therapeutic use , Nitric Oxide/therapeutic use , Piperazines/therapeutic use , Pulmonary Edema/etiology , Pulmonary Veno-Occlusive Disease/drug therapy , Sulfones/therapeutic use , Vasodilator Agents/therapeutic use , Adult , Dyspnea/etiology , Humans , Male , Pulmonary Veno-Occlusive Disease/complications , Purines/therapeutic use , Recurrence , Sildenafil Citrate , Tomography, X-Ray Computed
2.
Emerg Med J
; 23(8): 660, 2006 Aug.
Article
in English
| MEDLINE
| ID: mdl-16858113