A Prospective Study of Contracture of the Finger and its Management in a Tertiary Care Center.

BACKGROUND: When the range of motion between two finger segments, both active and passive, is restricted, finger contracture occurs. The aim of this study is to investigate the best procedure to eliminate finger contracture and the functional and esthetic results of the different surgical procedures. MATERIALS AND METHODS: A total of 31 patients with soft-tissue abnormalities of the hand were included in this prospective study. They underwent either contracture removal with K-wire and skin grafts or various flap procedures in the department of plastic surgery. Complaints of stiffness and discomfort were classified into five categories: none, mild, moderate, marked, and severe. The difficulty a person had in picking up objects, grasping, writing, etc., was used to determine the degree of disability. Absenteeism from work and surgical site infections were also recorded. RESULTS: The mean age was 20.25 years, with a mean age of 23.05 for men and 15.83 for women. Overall, most cases occurred in the age range of 3-10 years. For K-wire surgery with skin grafting, the typical time off work was 24 days. The average recovery time ranged from 15.2 days for skin grafts to 16.9 days for tenolysis, 28.33 days for groyne flaps, and 41 days for abdominal flaps. Of all cases, 12 (38.00%) had a fair result, 10 (31.04%) had a moderate result, and 9 (30.96%) had an excellent result. CONCLUSION: The most feasible method for treating these situations, which offers the greatest potential for a functional and cosmetic result, is contracture reduction with skin grafting.

Résumé Contexte:Lorsque l'amplitude de mouvement entre deux segments de doigts, actifs et passifs, est restreinte, une contracture des doigts se produit. Le Le but de cette étude est d'étudier la meilleure procédure pour éliminer la contracture des doigts et les résultats fonctionnels et esthétiques des différents interventions chirurgicales.Matériels et méthodes:Au total, 31 patients présentant des anomalies des tissus mous de la main ont été inclus dans cette étude prospective. étude. Ils ont subi soit une ablation des contractures avec du fil K et des greffes de peau, soit diverses procédures de lambeau dans le service de chirurgie plastique. Les plaintes de raideur et d'inconfort ont été classées en cinq catégories: aucune, légère, modérée, marquée et grave. La difficulté d'une personne qu'ils avaient à ramasser des objets, à les saisir, à écrire, etc., a été utilisé pour déterminer le degré d'incapacité. Absentéisme au travail et sur le site chirurgical des infections ont également été enregistrées.Résultats:L'âge moyen était de 20,25 ans, avec un âge moyen de 23,05 ans pour les hommes et de 15,83 ans pour les femmes. Dans l'ensemble, la plupart des cas sont survenus dans la tranche d'âge de 3 à 10 ans. Pour la chirurgie au fil K avec greffe de peau, le temps d'arrêt typique était de 24 jours. La moyenne le temps de récupération variait de 15,2 jours pour les greffes de peau à 16,9 jours pour la ténolyse, 28,33 jours pour les lambeaux d'épi et 41 jours pour les lambeaux abdominaux. Parmi tous les cas, 12 (38,00 %) ont eu un résultat passable, 10 (31,04 %) ont eu un résultat modéré et 9 (30,96 %) ont eu un excellent résultat.Conclusion:le plus La méthode réalisable pour traiter ces situations, qui offre le plus grand potentiel de résultat fonctionnel et esthétique, est la réduction des contractures. avec greffe de peau.

Photocatalytic Degradation of Orange G Dye by Using Bismuth Molybdate: Photocatalysis Optimization and Modeling via Definitive Screening Designs.

In the current study, Bismuth molybdate was synthesized using simple co-precipitation procedure, and their characterization was carried out by various methods such as FT-IR, SEM, and P-XRD. Furthermore, the photocatalytic degradation of Orange G (ORG) dye using synthesized catalyst under visible light irradiation was studied. Response surface Method was used for the optimization of process variables and degradation kinetics evaluated by modeling of experimental data. Based on the experimental design outcomes, the first-order model was proven as a practical correlation between selected factors and response. Further ANOVA analysis has revealed that only two out of six factors have a significant effect on ORG degradation, however ORG concentration and irradiation time indicated the significant effects sequentially. Maximum ORG degradation of approximately 96% was achieved by keeping process parameters in range, such as 1 g L-1 loading of catalyst, 50 mg L-1 concentration of ORG, 1.4 mol L-1 concentration of H2O2 at pH 7 and a temperature of 30 °C. Kinetics of ORG degradation followed the pseudo first order, and almost complete degradation was achieved within 8 h. The effectiveness of the Bi2MoO6/H2O2 photo-Fenton system in degradation reactions is due to the higher number of photo-generated e- available on the catalyst surface as a result of their ability to inhibit recombination of e- and h+ pair.

Nanotechnology-Based Approach to Combat Pandemic COVID 19: A Review.

The emergence of a novel Corona virus (COVID 19) originated on December 19 from China. The city of Wuhan, the capital city of Hubei province, China, is responsible for an outbreak of respiratory illness known as COVID 19 and it has been rapidly spread across the world claiming millions of lives. The sudden outbreak of novel Coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or 2019-nCoV), is a big concern for their speedy mitigation using the predictable treatment and creating its approach around the world. Researchers and doctors are in search of rapid diagnosis kit, drugs, and viral-resistant personal protective equipment (PPE) to clinical diagnosis, medication, and prevent the spread of COVID 19. A rational approach with adaptability and broad viewpoint to challenge the growing pain could be overcome by the application of appropriate technology. The nanotechnology-based approach can significantly serve the purpose of the current pandemic situation of COVID 19. But same time implementation of innovative and creative nanotech approach, there is a decisive need for the full knowledge of SARS-CoV-2 pathogenesis. Moreover, to defeat COVID 19, particularly nanotech-based system with their viral inhibitory properties to increase the effective nanotech approach is essential. In this scenario, this review aims to summarize the past, present, and future of nanotech-based systems that can be used to treat COVID 19, highlighting Nano-based compounds. Lastly, the potential application of the different category of Inorganic Nanomaterials/Inorganic organic conjugate /hybrid system and their practical applicability as suitable means for inspiring against COVID 19 has also been discussed.