ABSTRACT
INTRODUCTION: Intravitreal injections (IVT) of a drug aim to rapidly obtain effective concentrations greater than those that would be obtained by a periocular or intravenous injection. The objective of the present study is to demonstrate the contribution of IVT in the treatment of pathologies of the posterior segment of the eye. METHODOLOGY: We conducted a 21-month ambidirectional observational study from January 1, 2020, to September 30, 2021. We included by nonprobability sampling all consenting patients admitted for IVT at IOTA Teaching Hospital. RESULTS: During our study, 201 patients were collected out of 30 739 patients seen in consultation. The hospital frequency of IVT was 0.65%. There were 111 women and 90 men. The M/F ratio was 0.82. The number of patients who received IVT antibiotics was 135. Anti-VEGF was injected in 64 patients. Two patients received IVT corticosteroids. Complications frequently encountered were pain at upon injection (94.03%), IOP spike (11.94%) and cataract (7.46%). In our sample, we observed an improvement in visual acuity in 56.21% of cases and a reduction in macular edema in 45.16% of cases. DISCUSSION: The contribution of IVT in the treatment of vitreoretinal diseases is extraordinary. Rigorous observation of aseptic technique and good practices protects against infectious complications. CONCLUSION: IVT has allowed us to effectively treat various diseases of the vitreous and retina. IVT is a simple procedure, but it must be performed with the same aseptic technique as surgical procedures.
Subject(s)
Diabetic Retinopathy , Glucocorticoids , Male , Humans , Female , Glucocorticoids/therapeutic use , Triamcinolone Acetonide/adverse effects , Bevacizumab , Intravitreal Injections , Angiogenesis Inhibitors , Vascular Endothelial Growth Factor A , Diabetic Retinopathy/drug therapy , Treatment Outcome , Hospitals, TeachingABSTRACT
A baby born at home 14 hours earlier was brought to the neonatology department with bilateral upper palpebral chemosis with purulent secretions and pseudomembranes, with no general signs of infection. The gram staining of a secretion sample shows the presence of Neisseria gonorrhoeae. Intramuscular ceftriaxone treatment was initiated, combined with topical application of rifamycin, dexamethasone, and oxytetracycline. Complete healing without sequelae was obtained after two weeks. This case presents an opportunity to review this preventable pathology and its treatment. The only effective way to prevent it is to raise the awareness of disadvantaged population about the value of antenatal care.
Subject(s)
Ophthalmia Neonatorum/drug therapy , Anti-Bacterial Agents/therapeutic use , Ceftriaxone/therapeutic use , Dexamethasone/therapeutic use , Female , Glucocorticoids/therapeutic use , Humans , Infant, Newborn , Oxytetracycline/therapeutic use , Rifamycins/therapeutic useABSTRACT
La maladie de Stargardt est la plus connue des dystrophies maculaires juvéniles. Encore appelé fundus flavimaculatus, elle est une dystrophie maculaire héréditaire qui se transmet souvent sur un mode autosomique récessif et rarement sur un mode autosomique dominant. Elle est typiquement caractérisée par une déficience de la vision centrale, qui se manifeste autour de la première et ou de la deuxième décennie de la vie. Nous présentons les cas de deux frères et une soeur atteints de la maladie. La présentation, le diagnostic et les modalités thérapeutiques sont discutés.
Stargardt's disease is the best known of juvenile macular dystrophies. Also called fundus flavimaculatus, it is an inherited macular dystrophy that is often transmitted in an autosomal recessive fashion and rarely in an autosomal dominant mode. It is typically characterized by a deficiency of central vision, which manifests itself around the first and / or second decade of life. We present the cases of two brothers and one sister with the disease. Presentation, diagnosis and therapeutic modalities are discussed.
Subject(s)
Humans , Female , Stargardt Disease , Fluorescein AngiographyABSTRACT
But. Décrire les expériences visuelles des patients au cours de la chirurgie de la cataracte sous anesthésie péribulbaire. Patients et méthodes. Nous avons mené une étude transversale pendant une période d'un mois au CHU-IOTA (Bamako). Étaient inclus les adultes opérés de la cataracte sous anesthésie péribulbaire sans sédation. Les patients étaient interrogés 1 à 4 heures après l'intervention sur les sensations visuelles de l'Åil opéré, durant la chirurgie. Résultats. Deux cent sept (207) patients (105 hommes et 102 femmes) ont été retenus. Leur âge moyen était de 62,94 ans ± 12,5. L'acuité visuelle préopératoire des patients était comprise entre 1/10 et la perception lumineuse. Cent cinquante-huit (76,3%) patients ont rapporté des phénomènes visuels observés pendant l'intervention. Il s'agissait de la lumière (rapportée par 76,3% de patients), des couleurs (31,9%), des instruments (22,7%), des doigts du chirurgien (25,1%), de l'eau (27,1%) et des mouvements vagues (19,8%). Parmi eux, 38% étaient effrayés par ces sensations visuelles. Conclusion. Plus de trois-quarts de patients ont des expériences visuelles au cours de la chirurgie de la cataracte sous anesthésie péribulbaire. Certains sont effrayés par ces phénomènes visuels. Il est important de faire un counseling préopératoire approprié afin de réduire le stress des patients
Subject(s)
Anesthesia , Cataract , Cataract Extraction , Mali , Ophthalmologic Surgical Procedures , PatientsABSTRACT
INTRODUCTION: The treatment of cataract blindness is surgical, allowing restored vision. The purpose of this study was to evaluate the functional results of cataract surgery in adults in a tertiary care referral center. PATIENTS AND METHODS: Prospective study of 2012 eyes operated for adult cataract from September 1, 2009 to August 31, 2010 (12 months). The results were analyzed by the Monitoring Cataract Surgical Outcomes software (MCSO). The postoperative functional data and the causes of poor outcomes were identified. RESULTS: A total of 1044 women (51.9%) and 968 men (48.1%) underwent cataract surgery. Mean age was 65 years. Extracapsular cataract extraction (ECCE), and manual sutureless small incision cataract surgery (SICS) with posterior chamber IOL implantation in 98%, were the main surgical techniques. Functional results indicated that 45.5% of our patients had good visual acuity (≥3/10) with current spectacles, 33% had limited visual acuity (1/10-2/10), and 21.6% had poor visual acuity (<1/10). The proportion of patients with good results improved with best spectacle correction to 63%, vs. 22.9% with limited visual acuity and 14.1% with poor outcomes. The causes of poor outcomes were mainly related to surgical complications (42.1%) and refractive errors (34.8%). DISCUSSION: These results are inferior to WHO standards, which recommend a rate greater than or equal to 80% for good outcomes and a rate below 5% for bad outcomes. CONCLUSION: The identification of the causes of poor outcomes underscores the importance of improving surgical skills and the need for postoperative refraction.
