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1.
Nat Commun ; 15(1): 78, 2024 Jan 02.
Article in English | MEDLINE | ID: mdl-38167270

ABSTRACT

Discrete symmetries play an important role in particle physics with violation of CP connected to the matter-antimatter imbalance in the Universe. We report the most precise test of P, T and CP invariance in decays of ortho-positronium, performed with methodology involving polarization of photons from these decays. Positronium, the simplest bound state of an electron and positron, is of recent interest with discrepancies reported between measured hyperfine energy structure and theory at the level of 10-4 signaling a need for better understanding of the positronium system at this level. We test discrete symmetries using photon polarizations determined via Compton scattering in the dedicated J-PET tomograph on an event-by-event basis and without the need to control the spin of the positronium with an external magnetic field, in contrast to previous experiments. Our result is consistent with QED expectations at the level of 0.0007 and one standard deviation.

2.
Phys Med ; 118: 103301, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38290179

ABSTRACT

PURPOSE: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. METHODS: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J-PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread-Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J-PET scanner prototype dedicated to the proton beam range assessment. RESULTS: The investigations indicate that the double-layer cylindrical and triple-layer double-head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple-layer dual-head geometry. The results indicate that the double-layer cylindrical and triple-layer double-head configurations are the most promising for the clinical application, CONCLUSIONS:: We performed simulation studies demonstrating that the feasibility of the J-PET detector for PET-based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre-clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double-layer cylindrical and triple-layer dual-head J-PET geometry configurations seem promising for future clinical application.


Subject(s)
Proton Therapy , Protons , Feasibility Studies , Positron-Emission Tomography , Proton Therapy/methods , Phantoms, Imaging , Monte Carlo Method
3.
Sensors (Basel) ; 22(24)2022 Dec 19.
Article in English | MEDLINE | ID: mdl-36560366

ABSTRACT

The effective and safe detection of illicit materials, explosives in particular, is currently of growing importance taking into account the geopolitical situation and increasing risk of a terrorist attack. The commonly used methods of detection are based predominantly on metal detectors and georadars, which show only the shapes of the possible dangerous objects and do not allow for exact identification and risk assessment. A supplementary or even alternative method may be based on neutron activation analysis, which provides the possibility of a stoichiometric analysis of the suspected object and its non-invasive identification. One such sensor is developed by the SABAT collaboration, with its primary application being underwater threat detection. In this article, we present performance studies of this sensor, integrated with a mobile robot, in terms of the minimal detectable quantity of commonly used explosives in different environmental conditions. The paper describes the functionality of the used platform considering electronics, sensors, onboard computing power, and communication system to carry out manual operation and remote control. Robotics solutions based on modularized structures allow the extension of sensors and effectors that can significantly improve the safety of personnel as well as work efficiency, productivity, and flexibility.


Subject(s)
Explosive Agents , Robotics , Computer Simulation , Electronics , Neutrons
4.
Sci Adv ; 7(42): eabh4394, 2021 Oct 15.
Article in English | MEDLINE | ID: mdl-34644101

ABSTRACT

In vivo assessment of cancer and precise location of altered tissues at initial stages of molecular disorders are important diagnostic challenges. Positronium is copiously formed in the free molecular spaces in the patient's body during positron emission tomography (PET). The positronium properties vary according to the size of inter- and intramolecular voids and the concentration of molecules in them such as, e.g., molecular oxygen, O2; therefore, positronium imaging may provide information about disease progression during the initial stages of molecular alterations. Current PET systems do not allow acquisition of positronium images. This study presents a new method that enables positronium imaging by simultaneous registration of annihilation photons and deexcitation photons from pharmaceuticals labeled with radionuclides. The first positronium imaging of a phantom built from cardiac myxoma and adipose tissue is demonstrated. It is anticipated that positronium imaging will substantially enhance the specificity of PET diagnostics.

5.
PLoS One ; 12(11): e0186728, 2017.
Article in English | MEDLINE | ID: mdl-29176834

ABSTRACT

A novel plastic scintillator is developed for the application in the digital positron emission tomography (PET). The novelty of the concept lies in application of the 2-(4-styrylphenyl)benzoxazole as a wavelength shifter. The substance has not been used as scintillator dopant before. A dopant shifts the scintillation spectrum towards longer wavelengths making it more suitable for applications in scintillators of long strips geometry and light detection with digital silicon photomultipliers. These features open perspectives for the construction of the cost-effective and MRI-compatible PET scanner with the large field of view. In this article we present the synthesis method and characterize performance of the elaborated scintillator by determining its light emission spectrum, light emission efficiency, rising and decay time of the scintillation pulses and resulting timing resolution when applied in the positron emission tomography. The optimal concentration of the novel wavelength shifter was established by maximizing the light output and it was found to be 0.05 ‰ for cuboidal scintillator with dimensions of 14 mm x 14 mm x 20 mm.


Subject(s)
Benzoxazoles/chemistry , Magnetic Resonance Imaging , Positron-Emission Tomography , Scintillation Counting/instrumentation , Styrenes/chemistry , Tomography , Light , Molecular Weight , Polymerization , Spectrometry, Fluorescence , Temperature , Time Factors
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