Subject(s)
ADAMTS13 Protein/metabolism , Biomarkers/metabolism , Diabetes Mellitus, Type 1/metabolism , Gene Expression/genetics , Kidney Diseases/genetics , Kidney Diseases/metabolism , Kidney/metabolism , Liver/metabolism , Animals , Humans , Kidney/pathology , Liver/pathology , Male , Mice , Mice, Inbred C57BL , Up-RegulationABSTRACT
Bites from the recluse or brown spiders (genus Loxosceles) can cause necrotic lesions and systemic effects in humans throughout the world. In the state of Paraná, Brazil, loxoscelism is considered a serious public health problem, and Loxosceles intermedia Mello-Leitão (Araneae: Sicariidae) is associated with the majority of reported accidents. In the present research we evaluated the susceptibility of L. intermedia to pyrethroid insecticides currently used for the control of spiders in both field and laboratory conditions. In laboratory tests, the most active pesticides in descending order were microencapsulated lambda-cyhalothrin (LC50 = 0.023 mg/kg), nonmicroencapsulated lambda-cyhalothrin (LC50 = 0.047 mg/kg), deltamethrin (LC50 = 0.26 mg/kg), and cypermethrin (LC50 = 1.38 mg/kg). Cockroaches, Phoetalia circumvagans (Burmeister) (n = 30), killed with microencapsulated lambdacyalothrin, were offered to the spiders. L. intermedia fed on 63.3% of the dead cockroaches during the first 6 h of experiment; none of the spiders died during the subsequent 15 d. Microencapsulated lambdacyalothrin was chosen for application in two contiguous houses. The mean volume applied was 22.8 mg (AI)/m2. Dead spiders were found during all the inspections up to 60 d after the initial application. In total, 297 dead spiders were collected; 65.7% in the attic shared by the two homes, 10.8% inside the house that had most cracks and crevices sealed and 23.6% in the control house. The use of lambda-cyhalothrin-based products for L. intermedia control is discussed.
Subject(s)
Insecticides/pharmacology , Pyrethrins/pharmacology , Spiders/drug effects , Animals , Insect Control , Insecticide ResistanceABSTRACT
O presente trabalho teve como objetivo principal a inserção da teoria psicanalítica no universo escolar a partir da análise da produção científica (resumos) sobre este termo. Foi efetuada uma análise em 18 resumos científicos selecionados e presentes em duas Bases de Dados. O material foi trabalhado, através de uma análise, quantitativa e qualitativa. Os principais resultados indicaram haver carência de pesquisa em relação ao tema estudado. Os tópicos estudados se relacionaram às dificuldades de aprendizagem dos alunos. As propostas de intervenção teriam por igual interesse as questões preventivas e remediativas. A presente pesquisa mostrou ainda que falta à Psicanálise desenvolver bases sólidas para se inserir ao contexto escolar e as suas demais dimensões (família, relação professor-aluno, etc.). Entretanto, os estudos demonstraram que novas ações psicanalíticas estariam sendo desenvolvidas dentro de um contexto pedagógico e preventivo (AU)
