ABSTRACT
OBJECTIVE: The aim of this study was to conduct a systematic review of the healing potential of medicinal plants belonging to the Brazilian National List of Medicinal Plants of Interest to the Unified Health System (RENISUS). METHOD: PubMed and ScienceDirect databases were searched for relevant articles, regardless of the language, from 2010 to June 2016. Two reviewers independently assessed study eligibility. Articles were included if they presented evidence of healing potential of medicinal plants. Only those available as full and open access texts were considered. RESULTS: A total of 1381 articles met the inclusion criteria. Of these, 156 studies were considered eligible and were reviewed as full text. Following full analysis, 64 studies were included in this review. The studies covered 27 of the 71 plants belonging to RENISUS, nine of which are native to Brazil. In addition, two species are currently available in the Brazilian public health system as herbal medicine. CONCLUSION: This review may encourage and contribute to the appropriate use of medicinal plants in the public health system in Brazil.
Subject(s)
Phytotherapy , Plant Extracts/therapeutic use , Plants, Medicinal , Skin Ulcer/drug therapy , Wound Healing , Brazil , HumansABSTRACT
Espécies de bactérias podem apresentar a capacidade genética de adquirir e transmitir resistência contra agentes antibacterianos, tornando-se multi-resistentes aos medicamentos disponíveis. Esta revisão sistemática objetivou quantificar os estudos clínicos que referem potencial terapêutico sobre doenças antibacterianas a partir do estudo de plantas constantes na Relação Nacional de Plantas Medicinais de Interesse ao Sistema Único de Saúde publicados entre 2010 e fevereiro de 2013 em três bases de dados científicas (SciELO, Science Direct e Springer). Dos 21.357 artigos encontrados nas bases de dados, tal análise resultou na seleção de 19 estudos de interesse, com diferentes plantas da relação. Os resultados encontrados neste estudo contribuem para que sejam tratadas novas discussões sobre alternativas terapêuticas aos tratamentos convencionais de doenças bacterianas, empregando plantas como um adjuvante.
Bacterial species may have the genetic ability to acquire and convey resistance to antibacterial agents, becoming multi-drug resistant available. This systematic review aimed to quantify the clinical studies which reported on antibacterial therapeutic potential diseases from the study of the plants in RENISUS, published between 2010 and February 2013 in three scientific databases (SciELO, Science Direct and Springer). Of the 21 357 articles found in databases such analysis resulted in selection of 19 studies of interest with different plants RENISUS. The results of this study contribute to be treated further discussions on alternative therapies with conventional treatments of bacterial diseases, using plants as an adjuvant.
Subject(s)
Humans , Plants, Medicinal , Bacteria , Health , Drug Resistance, Microbial , Systematic Review , PhytotherapyABSTRACT
A inflamação é uma resposta aguda à lesão do tecido responsável por produzir sintomas característicos que levam a alterações na homeostase do tecido e no fluxo sanguíneo, sendo um mecanismo de defesa do sistema imune. No entanto, a inflamação crônica é a causa de inúmeras doenças como câncer, arteriosclerose, diabetes e doenças neurodegenerativas. Grande parte dos fármacos anti-inflamatórios exercem inúmeros efeitos colaterais que podem restringir seu uso. Uma alternativa a tais medicamentos são as plantas medicinais, que oferecem uma importante perspectiva na identificação de compostos bioativos. Esta revisão sistemática objetivou quantificar os estudos clínicos que referem potencial terapêutico sobre doenças inflamatórias a partir do estudo de plantas da RENISUS, publicados entre 2010 e fevereiro de 2013 em três bases de dados científicas (SciELO, Science Direct e Springer). Dos 21.357 artigos encontrados nas bases de dados, a análise dos artigos foi realizada inicialmente a partir da leitura do título do periódico, os artigos elegidos foram posteriormente avaliados quanto ao Abstract. Por fim, com os artigos escolhidos nesta etapa, foi analisado o texto completo. Tal análise resultou na seleção de 44 estudos de interesse, que tratavam de 20 plantas diferentes da RENISUS.(AU)
The inflammation is a response to acute tissue injury responsible for producing characteristic symptoms that lead to changes in tissue homeostasis and blood flow, as a defense mechanism of the immune system. However, chronic inflammation is a cause of many diseases like cancer, arteriosclerosis, diabetes and neurodegenerative diseases. Most anti-inflammatory drugs exert significant side effects that may limit their use. An alternative to such drugs are the medicinal plants, which provide an important approach for the identification of bioactive compounds. This systematic review aimed to quantify the clinical studies that relate therapeutic potential for inflammatory diseases from the study of plants RENISUS, published between 2010 and February 2013 in three scientific databases (SciELO, Science Direct and Springer). Of the 21 357 articles found in databases, analysis of articles was originally made from the title of journal reading, the chosen articles were subsequently assessed for Abstract. Finally, Articles chosen at this stage, the full text was analyzed. This analysis resulted in the selection of 44 studies of interest, which dealt with 20 different plants RENISUS.(AU)