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1.
Précoma, Dalton Bertolim; Oliveira, Gláucia Maria Moraes de; Simão, Antonio Felipe; Dutra, Oscar Pereira; Coelho, Otávio Rizzi; Izar, Maria Cristina de Oliveira; Póvoa, Rui Manuel dos Santos; Giuliano, Isabela de Carlos Back; Filho, Aristóteles Comte de Alencar; Machado, Carlos Alberto; Scherr, Carlos; Fonseca, Francisco Antonio Helfenstein; Filho, Raul Dias dos Santos; Carvalho, Tales de; Avezum Jr, Álvaro; Esporcatte, Roberto; Nascimento, Bruno Ramos; Brasil, David de Pádua; Soares, Gabriel Porto; Villela, Paolo Blanco; Ferreira, Roberto Muniz; Martins, Wolney de Andrade; Sposito, Andrei C; Halpern, Bruno; Saraiva, José Francisco Kerr; Carvalho, Luiz Sergio Fernandes; Tambascia, Marcos Antônio; Coelho-Filho, Otávio Rizzi; Bertolami, Adriana; Filho, Harry Correa; Xavier, Hermes Toros; Neto, José Rocha Faria; Bertolami, Marcelo Chiara; Giraldez, Viviane Zorzanelli Rocha; Brandão, Andrea Araújo; Feitosa, Audes Diógenes de Magalhães; Amodeo, Celso; Souza, Dilma do Socorro Moraes de; Barbosa, Eduardo Costa Duarte; Malachias, Marcus Vinícius Bolívar; Souza, Weimar Kunz Sebba Barroso de; Costa, Fernando Augusto Alves da; Rivera, Ivan Romero; Pellanda, Lucia Campos; Silva, Maria Alayde Mendonça da; Achutti, Aloyzio Cechella; Langowiski, André Ribeiro; Lantieri, Carla Janice Baister; Scholz, Jaqueline Ribeiro; Ismael, Silvia Maria Cury; Ayoub, José Carlos Aidar; Scala, Luiz César Nazário; Neves, Mario Fritsch; Jardim, Paulo Cesar Brandão Veiga; Fuchs, Sandra Cristina Pereira Costa; Jardim, Thiago de Souza Veiga; Moriguchi, Emilio Hideyuki; Moriguchi, Emilio Hideyuki; Schneider, Jamil Cherem; Assad, Marcelo Heitor Vieira; Kaiser, Sergio Emanuel; Lottenberg, Ana Maria; Magnoni, Carlos Daniel; Miname, Marcio Hiroshi; Lara, Roberta Soares; Herdy, Artur Haddad; Araújo, Cláudio Gil Soares de; Milani, Mauricio; Silva, Miguel Morita Fernandes da; Stein, Ricardo; Lucchese, Fernando Antônio; Nobre, Fernando; Griz, Hermilo Borba; Magalhães, Lucélia Batista Neves Cunha; Borba, Mario Henrique Elesbão de; Pontes, Mauro Ricardo Nunes; Mourilhe-Rocha, Ricardo.
Arq. bras. cardiol ; 116(4): 855-855, abr. 2021.
Article in Portuguese | LILACS | ID: biblio-1285194
2.
Arq Bras Cardiol ; 113(4): 787-891, 2019 11 04.
Article in English, Portuguese | MEDLINE | ID: mdl-31691761
3.
Précoma, Dalton Bertolim; Oliveira, Gláucia Maria Moraes de; Simão, Antonio Felipe; Dutra, Oscar Pereira; Coelho, Otávio Rizzi; Izar, Maria Cristina de Oliveira; Póvoa, Rui Manuel dos Santos; Giuliano, Isabela de Carlos Back; Filho, Aristóteles Comte de Alencar; Machado, Carlos Alberto; Scherr, Carlos; Fonseca, Francisco Antonio Helfenstein; Filho, Raul Dias dos Santos; Carvalho, Tales de; Avezum Jr, Álvaro; Esporcatte, Roberto; Nascimento, Bruno Ramos; Brasil, David de Pádua; Soares, Gabriel Porto; Villela, Paolo Blanco; Ferreira, Roberto Muniz; Martins, Wolney de Andrade; Sposito, Andrei C; Halpern, Bruno; Saraiva, José Francisco Kerr; Carvalho, Luiz Sergio Fernandes; Tambascia, Marcos Antônio; Coelho-Filho, Otávio Rizzi; Bertolami, Adriana; Filho, Harry Correa; Xavier, Hermes Toros; Neto, José Rocha Faria; Bertolami, Marcelo Chiara; Giraldez, Viviane Zorzanelli Rocha; Brandão, Andrea Araújo; Feitosa, Audes Diógenes de Magalhães; Amodeo, Celso; Souza, Dilma do Socorro Moraes de; Barbosa, Eduardo Costa Duarte; Malachias, Marcus Vinícius Bolívar; Souza, Weimar Kunz Sebba Barroso de; Costa, Fernando Augusto Alves da; Rivera, Ivan Romero; Pellanda, Lucia Campos; Silva, Maria Alayde Mendonça da; Achutti, Aloyzio Cechella; Langowiski, André Ribeiro; Lantieri, Carla Janice Baister; Scholz, Jaqueline Ribeiro; Ismael, Silvia Maria Cury; Ayoub, José Carlos Aidar; Scala, Luiz César Nazário; Neves, Mario Fritsch; Jardim, Paulo Cesar Brandão Veiga; Fuchs, Sandra Cristina Pereira Costa; Jardim, Thiago de Souza Veiga; Moriguchi, Emilio Hideyuki; Schneider, Jamil Cherem; Assad, Marcelo Heitor Vieira; Kaiser, Sergio Emanuel; Lottenberg, Ana Maria; Magnoni, Carlos Daniel; Miname, Marcio Hiroshi; Lara, Roberta Soares; Herdy, Artur Haddad; Araújo, Cláudio Gil Soares de; Milani, Mauricio; Silva, Miguel Morita Fernandes da; Stein, Ricardo; Lucchese, Fernando Antônio; Nobre, Fernando; Griz, Hermilo Borba; Magalhães, Lucélia Batista Neves Cunha; Borba, Mario Henrique Elesbão de; Pontes, Mauro Ricardo Nunes; Mourilhe-Rocha, Ricardo.
Arq. bras. cardiol ; 113(4): 787-891, Oct. 2019. tab, graf, ilus
Article in English | CONASS, Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP | ID: biblio-1150799
4.
Einstein (Sao Paulo) ; 12(1): 120-5, 2014.
Article in English | MEDLINE | ID: mdl-24728258

ABSTRACT

Obesity is a chronic disease characterized by the excessive accumulation of body fat that is harmful to the individuals. Respiratory disorders are among the comorbidities associated with obesity. This study had the objective of investigating the alterations in respiratory function that affect obese individuals. A systematic review was performed, by selecting publications in the science databases MEDLINE and LILACS, using PubMed and SciELO. The articles that assessed pulmonary function by plethysmography and/or spirometry in obese individuals aged under 18 years were included. The results demonstrated that the obese individuals presented with a reduction in lung volume and capacity as compared to healthy individuals. Reduction of total lung capacity and reduction of forced vital capacity, accompanied by reduction of the forced expiratory volume after one second were the most representative findings in the samples. The articles analyzed proved the presence of a restrictive respiratory pattern associated with obesity.


Subject(s)
Lung/physiopathology , Obesity/physiopathology , Body Mass Index , Female , Humans , Male , Obesity/complications , Plethysmography , Respiratory Function Tests , Respiratory Tract Diseases/etiology , Respiratory Tract Diseases/physiopathology , Total Lung Capacity/physiology
5.
J. bras. nefrol ; 36(2): 171-175, Apr-Jun/2014. tab, graf
Article in Portuguese | LILACS | ID: lil-714658

ABSTRACT

Introdução: A hipertrofia ventricular esquerda (HVE) é um fator preditor independente de risco cardiovascular em pacientes com doença renal crônica (DRC) em hemodiálise (HD). Objetivo: Mostrar a utilidade da radiografia de tórax no diagnóstico de HVE em pacientes com DRC em HD. Métodos: Estudo transversal que incluiu 100 pacientes (58 homens e 42 mulheres), idade média de 46,2 ± 14,0 anos, com DRC de todas as etiologias, há pelo menos seis meses em HD. Foram obtidos ecocardiograma e radiografia de tórax dos pacientes, sempre até uma hora após o término das sessões de HD. Resultados: A HVE foi detectada em 83 pacientes (83%), dos quais 56 (67,4%) apresentavam o padrão concêntrico e 27 (32,6%) a padrão excêntrico de HVE. Cardiomegalia - definida por índice cardiotorácico (ICT) > 0,5 - esteve presente em 61 pacientes (61%). Foram os seguintes os valores de sensibilidade, especificidade e acurácia, respectivamente, para a variável ICT: 66,2%, 70,5% e 68,0%. A correlação de Pearson entre ICT e índice de massa do ventrículo esquerdo (IMVE) foi de 0,552 (p < 0,05) e razão de verossimilhança positivo de 2,2. Conclusão: A radiografia de tórax é um exame seguro e útil como ferramenta diagnóstica de HVE em pacientes com DRC em HD. .


Introduction: Left ventricular hypertrophy (LVH) is an independent predictor of cardiovascular risk in patients with chronic renal disease (CRD) on hemodialysis (HD). Objective: To show the usefulness of chest radiography in the diagnosis of LVH in CRD patients on HD. Methods: Cross-sectional study including 100 patients (58 men and 42 women), mean age 46.2 ± 14.0 years, with CRD of all causes, for at least six months on HD. Were obtained echocardiogram and chest x-rays of patients, always up to one hour after the end of HD sessions. Results: LVH was detected in 83 patients (83%), of whom 56 (67.4%) had the concentric pattern and 27 (32.6%) with eccentric pattern of LVH. Cardiomegaly - defined by cardiothoracic index (CTI) > 0.5 - was present in 61 patients (61%). The following were the sensitivity, specificity and accuracy, respectively, for the variable ICT: 66.2%, 70.5% and 68.0%. The Pearson correlation between ICT and index of left ventricular mass (LVMI) was 0.552 (p < 0.05) and positive likelihood ratio of 2.2. Conclusion: Chest radiography is a safe and useful as a diagnostic tool of LVH in CKD patients on HD. .


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Hypertrophy, Left Ventricular/etiology , Renal Insufficiency, Chronic/complications , Cross-Sectional Studies , Hypertrophy, Left Ventricular , Hypertrophy, Left Ventricular , Radiography, Thoracic , Renal Dialysis , Renal Insufficiency, Chronic/therapy
6.
Einstein (Säo Paulo) ; 12(1): 120-125, Jan-Mar/2014. graf
Article in English | LILACS | ID: lil-705790

ABSTRACT

Obesity is a chronic disease characterized by the excessive accumulation of body fat that is harmful to the individuals. Respiratory disorders are among the comorbidities associated with obesity. This study had the objective of investigating the alterations in respiratory function that affect obese individuals. A systematic review was performed, by selecting publications in the science databases MEDLINE and LILACS, using PubMed and SciELO. The articles that assessed pulmonary function by plethysmography and/or spirometry in obese individuals aged under 18 years were included. The results demonstrated that the obese individuals presented with a reduction in lung volume and capacity as compared to healthy individuals. Reduction of total lung capacity and reduction of forced vital capacity, accompanied by reduction of the forced expiratory volume after one second were the most representative findings in the samples. The articles analyzed proved the presence of a restrictive respiratory pattern associated with obesity.


A obesidade é uma doença crônica, caracterizada pelo acúmulo excessivo de gordura corporal, que ocasiona prejuízos ao indivíduo. Dentre as comorbidades associadas à obesidade, estão as disfunções respiratórias. O presente estudo teve por objetivo investigar as alterações da função pulmonar que acometem indivíduos obesos. Foi realizada uma revisão sistemática, por meio da seleção de publicações nas bases científicas de dados MEDLINE e LILACS, por meio do PubMed e SciELO. Foram inclusos os trabalhos que avaliaram a função pulmonar, por meio de pletismografia e/ou espirometria, em indivíduos obesos maiores de 18 anos. Os resultados demonstraram que os indivíduos obesos apresentaram redução dos volumes e capacidades pulmonares quando comparados a indivíduos eutróficos. Redução da capacidade pulmonar total e redução da capacidade vital forçada, acompanhadas de redução do volume expiratório forçado após um segundo, foram os achados mais representativos dentre as amostras. Os trabalhos analisados comprovam a presença de padrão respiratório restritivo associado à obesidade.


Subject(s)
Female , Humans , Male , Lung/physiopathology , Obesity/physiopathology , Body Mass Index , Obesity/complications , Plethysmography , Respiratory Function Tests , Respiratory Tract Diseases/etiology , Respiratory Tract Diseases/physiopathology , Total Lung Capacity/physiology
7.
Rev. bras. cardiol. (Impr.) ; 26(5): 329-336, set.-out. 2013. tab
Article in Portuguese | LILACS | ID: lil-704447

ABSTRACT

Fundamentos: Nas elevações agudas da hipertensão arterial sistêmica (HAS), a intervenção imediata e cuidadosa é essencial para a redução da morbidade e da mortalidade decorrentes dessa complicação.Objetivos: Identificar a frequência de urgência hipertensiva (UH), emergência hipertensiva (EH), pseudocrise hipertensiva (PCH) e elevação sintomática da pressão arterial (ESPA). Comparar o conhecimento prévio da HAS, o uso prévio de anti-hipertensivos (AH), os níveis pressóricos apresentados e os desfechos hospitalares nos grupos estudados. Métodos: Estudo analítico, casos e controles, seleção consecutiva e análise retrospectiva de pacientes com elevação aguda da pressão arterial, admitidos na emergência de hospital cardiológico de atendimento privado, entre 11/2009 e 10/2010. Casos representam os pacientes com crise hipertensiva (CH): UH+EH. Controles representam os pacientes sem CH: PCH+ESPA. Resultados: Foram estudados 216 atendimentos relacionados à HAS, 113 (52,0 %) mulheres, idade entre 25-95 anos, mediana de 58 anos. EH foi diagnosticada em 18 (8,0 %) pacientes, UH em 29 (13,0 %), PCH em 8 (4,0 %) e ESPA em 161 (75,0 %). Diagnóstico e tratamento prévio de HAS não diferiram nos grupos com e sem CH. Sintomas cardiovasculares, prescrição de AH e internação foram mais frequentes naqueles com CH (p<0,05); mas apenas 7,0 % dos pacientes não receberam AH. Não houve óbitos.Conclusões: Na população estudada, CH foi identificada em 21,0 % dos casos e o tratamento AH foi aplicado em 93,0 % dos casos. O diagnóstico de HAS e tratamento AH prévio não diferiram naqueles pacientes com e sem CH.


Background: For systemic high blood pressure (SHBP) surges, immediate and careful intervention is essential for reducing morbidity and mortality rates related to this complication.Objectives: To identify the frequency of hypertensive urgency (HU), hypertensive emergency (HE), pseudo-hypertensive crisis (PHC) and symptomatic blood pressure increase (SBPI). Compare prior knowledge of SHBP, previous use of anti-hypertensive (AH), pressure levels presented and hospital outcomes in both groups. Methods: Analytical, case and control study with consecutive selection and retrospective analysis of patients with acute increase in blood pressure, admitted to the emergency cardiac care unit at a private hospital, between November 2009 and October 2010. The cases were patients with hypertensive crisis (HC): HU + HE. The controls were patients without HC: PHC + SBPI. Results: A total of 216 cases related to SHBP were studied, consisting of 113 (52 %) women between 25 and 95 years old, with a median age of 58 years. HE was diagnosed in 18 (8 %) patients, HU in 29 (13 %), PHC in 8 (4 %) and SBPI in 161 (75 %). Prior diagnosis and treatment of SHBP did not differ between the groups with and without HC. Cardiovascular symptoms, hospitalization and AH prescriptions were more frequent among those with HC (p <0.05), but only 7 % of the patients did not receive AH. There were no deaths. Conclusions: In this population studied, HC was identified in 21 % of the cases and AH treatment was administered in 93 % of cases diagnosed with SHBP. Prior AH treatment did not differ among patients with and without HC.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Stroke/complications , Stroke/diagnosis , Pulmonary Edema/complications , Hypertension, Malignant/complications , Hypertension, Malignant/mortality , Risk Factors , Heart Failure
8.
Rev. Assoc. Med. Bras. (1992) ; 59(4): 381-386, jul.-ago. 2013. tab
Article in Portuguese | LILACS | ID: lil-685531

ABSTRACT

OBJETIVO: Comparar a frequência dos fatores de risco cardiovascular (FRCV) em obesos com indicação de gastroplastia no pré-operatório e após o sexto mês e o primeiro ano do procedimento, em usuários do Sistema Único de Saúde. MÉTODOS: Foi realizado estudo observacional, longitudinal, prospectivo e analítico, com seleção consecutiva de obesos com indicação cirúrgica, encaminhados para avaliação cardiológica pré-operatória. O protocolo foi constituído de: história clínica, exame físico, eletrocardiograma, ecocardiograma e dosagens bioquímicas. No presente estudo, foram analisadas as seguintes variáveis: peso, índice de massa corporal (IMC), circunferência abdominal (CA), hipertensão arterial Sistêmica (HAS), diabetes mellitus-tipo 2 (DM), dislipidemia (colesterol LDL elevado; colesterol HDL baixo; hipertrigliceridemia) e síndrome metabólica (SM). Para análise estatística foram utilizados os métodos do Qui-quadrado e Tukey-Kramer. RESULTADOS: A amostra foi constituída de 96 obesos. Desses, 86 eram mulheres com idades entre 18 e 58 anos (mediana de 35 anos). Ao final de seis meses, foi observada redução significante de 88%, 95%, 71%, 89% e 80% na frequência de HAS, colesterol LDL elevado, hipertrigliceridemia, DM e SM. Apenas ao final de 12 meses houve significante e modesta redução na frequência de colesterol HDL baixo (24%) e CA anormal (31%). Em seis meses e um ano ,o peso e o IMC sofreram reduções respectivas de 33,4 e 44,3 kg e de 13,1 e 17,2 kg/m². CONCLUSÃO: O impacto positivo na perda de peso, na redução do IMC, da CA e da frequência dos FRCM mostrou-se extremamente significante após seis meses, e se manteve após um ano da gastroplastia.


OBJECTIVE: To compare the frequency of cardiovascular risk factors (CVRFs) in obese patients Obesity of the Brazilian Unified Health System (Sistema Único de Saúde - SUS) with indication of bariatric surgery during the preoperative period and after the sixth month and the first year of the procedure. METHODS: An observational, longitudinal, prospective, and analytical study was performed, with consecutive selection of obese patients with indication for surgery referred to preoperative cardiac evaluation. The protocol consisted of: medical history, physical examination, electrocardiogram, echocardiogram, and biochemical analysis. This study analyzed the following variables:weight, body mass index (BMI),waist circumference (WC), systemic arterial hypertension (SAH), diabetes mellitus type 2(DM), dyslipidemia (high LDL cholesterol; low HDL cholesterol; hypertriglyceridemia), and metabolic syndrome (MS). The chi-squared test and the Tukey-Kramer method were used for statistical analysis. RESULTS: The sample was composed of 96 obese people, among which 86 were women, aged between 18 and 58 years old (median 35 years old). At the end of six months, significant reductions of 88%, 95%, 71%, 89%, and 80% in the frequency of SAH, high LDL cholesterol, hypertriglyceridemia, DM, and MS could already be observed. A significant and small reduction in the frequency of low HDL cholesterol (24%) and abnormal WC (31%) was observed only at the end of 12 months. After six months and one year, weight and BMI experienced reductions of 33.4 kg and 44.3 kg, and 13.1 kg/m2 and 17.2 kg/m2, respectively. CONCLUSION: The positive impact on weight loss and the reduction in BMI, WC, and in the frequency of CVRFs are already extremely significant after six months and remain so one year after bariatric surgery.


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Bariatric Surgery , /epidemiology , Dyslipidemias/epidemiology , Hypertension/epidemiology , Metabolic Syndrome/epidemiology , Obesity, Morbid/complications , Obesity, Morbid/surgery , Postoperative Period , Preoperative Period , Prospective Studies
9.
Rev Assoc Med Bras (1992) ; 59(4): 381-6, 2013.
Article in English, Portuguese | MEDLINE | ID: mdl-23866938

ABSTRACT

OBJECTIVE: To compare the frequency of cardiovascular risk factors (CVRFs) in obese patients of the Brazilian Unified Health System (Sistema Único de Saúde - SUS) with indication of bariatric surgery during the preoperative period and after the sixth month and the first year of the procedure. METHODS: An observational, longitudinal, prospective, and analytical study was performed, with consecutive selection of obese patients with indication for surgery referred to preoperative cardiac evaluation. The protocol consisted of: medical history, physical examination, electrocardiogram, echocardiogram, and biochemical analysis. This study analyzed the following variables: weight, body mass index (BMI), waist circumference (WC), systemic arterial hypertension (SAH), diabetes mellitus type 2(DM), dyslipidemia (high LDL cholesterol; low HDL cholesterol; hypertriglyceridemia), and metabolic syndrome (MS). The chi-squared test and the Tukey-Kramer method were used for statistical analysis. RESULTS: The sample was composed of 96 obese people, among which 86 were women, aged between 18 and 58 years old (median 35 years old). At the end of six months, significant reductions of 88%, 95%, 71%, 89%, and 80% in the frequency of SAH, high LDL cholesterol, hypertriglyceridemia, DM, and MS could already be observed. A significant and small reduction in the frequency of low HDL cholesterol (24%) and abnormal WC (31%) was observed only at the end of 12 months. After six months and one year, weight and BMI experienced reductions of 33.4kg and 44.3kg, and 13.1kg/m(2) and 17.2kg/m(2), respectively. CONCLUSION: The positive impact on weight loss and the reduction in BMI, WC, and in the frequency of CVRFs are already extremely significant after six months and remain so one year after bariatric surgery.


Subject(s)
Bariatric Surgery , Diabetes Mellitus, Type 2/epidemiology , Dyslipidemias/epidemiology , Hypertension/epidemiology , Metabolic Syndrome/epidemiology , Obesity, Morbid/complications , Obesity, Morbid/surgery , Adult , Female , Humans , Male , Middle Aged , Postoperative Period , Preoperative Period , Prospective Studies , Young Adult
10.
Arq Bras Cardiol ; 97(2): 141-7, 2011 Aug.
Article in English, Portuguese, Spanish | MEDLINE | ID: mdl-22002029

ABSTRACT

BACKGROUND: Recent studies describe the participation of reactive oxygen and nitrogen species in hypertension. OBJECTIVE: To identify the redox imbalance in the blood of hypertensive. METHODS: Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH), vitamin C, transferrin, ceruloplasmin, malondialdehyde (MDA) and carbonyl group were quantified in the blood of 20 hypertensives and 21 controls. The individuals had a Body Mass Index of ≥ 18.5 and ≤ 30 kg/m(2), glycemia ≤ 100 mg/dL, serum cholesterol ≤ 200 mg/dL, and were nonsmokers, non-pregnant and non-lactating women, non-users of alopurinol and probucol, with hypertensives on antihypertensive medication. All individuals underwent a preparatory period of 4 weeks without alcohol, vitamin supplements, dexamethasone and paracetamol. RESULTS: Reduced levels of CAT (p 0.013), GSH (p 0.003) and MDA (p 0.014), and high levels of GPx (p 0.001) and ceruloplasmin (p 0.015) were obtained in the hypertensive group compared with controls. A positive correlation between systolic pressure and MDA in hypertensive and diastolic pressure and CAT in controls was obtained. CONCLUSION: The data obtained suggest that the hypertensives were in redox imbalance, despite the possibly attenuating effect of their antihypertensive medication.


Subject(s)
Antioxidants/analysis , Hypertension/blood , Oxidative Stress/physiology , Antihypertensive Agents/therapeutic use , Antioxidants/metabolism , Biomarkers/blood , Brazil , Catalase/blood , Epidemiologic Methods , Female , Glutathione/blood , Humans , Hypertension/drug therapy , Male , Malondialdehyde/blood , Middle Aged , Oxidation-Reduction , Oxidative Stress/drug effects
11.
Arq. bras. cardiol ; 97(2): 141-147, ago. 2011. tab
Article in Portuguese | LILACS | ID: lil-601783

ABSTRACT

FUNDAMENTO: Estudos recentes descrevem a participação de espécies reativas de oxigênio e nitrogênio na hipertensão. OBJETIVO: Identificar o desbalanço redox em sangue de hipertensos. MÉTODOS: Superóxido dismutase (SOD), catalase (CAT), glutationa peroxidase (GPx), glutationa (GSH), vitamina C, transferrina, ceruloplasmina, malondialdeído (MDA) e o grupo carbonila, foram quantificados no sangue de 20 hipertensos e 21 controles. Os indivíduos tinham um Índice de Massa Corporal de > 18,5 e < 30 kg/m², glicemia < 100 mg/dL, colesterol sérico < 200 mg/dL, e eram mulheres não fumantes, não grávidas e não lactantes, não usuárias de alopurinol e probucol, e hipertensos em medicação anti-hipertensiva. Todos os indivíduos foram submetidos a um período preparatório de quatro semanas sem álcool, suplementos vitamínicos, dexametasona e paracetamol. RESULTADOS: Níveis reduzidos de CAT (p = 0,013), GSH ( p = 0,003) e MDA (p = 0,014), e altos níveis de GPx (p = 0,001) e ceruloplasmina (p = 0,015) foram obtidos no grupo de hipertensos, em comparação com os controles. Foi verificada uma correlação positiva entre a pressão sistólica e o MDA nos hipertensos e diastólica e CAT nos controles. CONCLUSÃO: Os dados obtidos são sugestivos de que os hipertensos apresentavam desequilíbrio em reações redox, a despeito do possível efeito atenuante de sua medicação anti-hipertensiva.


BACKGROUND: Recent studies describe the participation of reactive oxygen and nitrogen species in hypertension. OBJECTIVE: To identify the redox imbalance in the blood of hypertensive. METHODS: Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH), vitamin C, transferrin, ceruloplasmin, malondialdehyde (MDA) and carbonyl group were quantified in the blood of 20 hypertensives and 21 controls. The individuals had a Body Mass Index of > 18.5 and < 30 kg/m², glycemia < 100 mg/dL, serum cholesterol < 200 mg/dL, and were nonsmokers, non-pregnant and non-lactating women, non-users of alopurinol and probucol, with hypertensives on antihypertensive medication. All individuals underwent a preparatory period of 4 weeks without alcohol, vitamin supplements, dexamethasone and paracetamol. RESULTS: Reduced levels of CAT (p 0.013), GSH (p 0.003) and MDA (p 0.014), and high levels of GPx (p 0.001) and ceruloplasmin (p 0.015) were obtained in the hypertensive group compared with controls. A positive correlation between systolic pressure and MDA in hypertensive and diastolic pressure and CAT in controls was obtained. CONCLUSION: The data obtained suggest that the hypertensives were in redox imbalance, despite the possibly attenuating effect of their antihypertensive medication.


FUNDAMENTO: Estudios recientes describen la participación de especies reactivas de oxígeno y nitrógeno en la hipertensión. OBJETIVO: Identificar el desequilíbrio redox em la sangre de los hipertensos MÉTODOS: El Superóxido dismutasa (SOD), catalasa (CAT), glutationa peroxidasa (GPx), glutationa (GSH), vitamina C, transferrina, ceruloplasmina, malondialdehído (MDA) y el grupo carbonilo, fueron cuantificados en la sangre de 20 hipertensos y 21 controles. Los individuos tenían un Índice de Masa Corporal de > 18,5 y < 30 kg/m², glicemia < 100 mg/dL, colesterol sérico < 200 mg/dL, y eran mujeres no fumadoras, no grávidas y no lactantes, no usuarias de alopurinol y probucol, con hipertensos sometidos a medicación antihipertensiva. Todos los individuos fueron sometidos a un período preparatorio de cuatro semanas sin alcohol, suplementos vitamínicos, dexametasona y paracetamol. RESULTADOS: Niveles reducidos de CAT (p = 0,013), GSH (p = 0,003) y MDA (p = 0,014), y altos niveles de GPx (p = 0,001) y ceruloplasmina (p = 0,015) fueron obtenidos en el grupo de hipertensos, en comparación con los controles. Fue obtenida una correlación positiva entre la presión sistólica y el MDA en la presión de hipertensos y diastólica y CAT en los controles. CONCLUSIÓN: Los datos obtenidos son sugestivos de que los hipertensos presentaban desequilibrio en reacciones de reducción y oxidación, a despecho del posible efecto atenuante de su medicación antihipertensiva.


Subject(s)
Female , Humans , Male , Middle Aged , Antioxidants/analysis , Hypertension/blood , Oxidative Stress/physiology , Antihypertensive Agents/therapeutic use , Antioxidants/metabolism , Brazil , Biomarkers/blood , Catalase/blood , Epidemiologic Methods , Glutathione/blood , Hypertension/drug therapy , Malondialdehyde/blood , Oxidation-Reduction , Oxidative Stress/drug effects
12.
Rev. bras. ecocardiogr. imagem cardiovasc ; 23(3): 109-111, jul.-set. 2010. ilus
Article in Portuguese | LILACS | ID: lil-556786

ABSTRACT

Os tumores primários benignos do coração são malformações muito raras. Apresentamos dois relatos de tumores: mixoma e rabdomioma, que embora benignos do ponto de vista histológicos, apresentam diferenças importantes na sua apresentação clínica e morfológica. nas características ecocardiográficas, na sua localização intracardíaca e número de tumorações. A idade do paciente é importante para investigação inicial.


Subject(s)
Humans , Male , Female , Infant, Newborn , Middle Aged , Heart Neoplasms/complications , Heart Neoplasms/diagnosis , Rhabdomyoma
13.
Arq. bras. cardiol ; 95(2): 159-165, ago. 2010. tab
Article in Portuguese | LILACS | ID: lil-557843

ABSTRACT

FUNDAMENTO: Sedentarismo é fator predisponente ao aparecimento/piora de outros fatores de risco cardiovascular, particularmente obesidade. OBJETIVO: Estabelecer nível de atividade física (NAF) e número diário de horas de TV (HTV) e a associação e/ou correlação destas variáveis com faixa etária, sexo, classe econômica, escola pública/privada, excesso de peso e obesidade, em crianças/adolescentes. MÉTODOS: Estudo transversal, base populacional escolar, ensino público e privado, fundamental e médio. Cálculo da amostra baseado na menor prevalência esperada de inúmeras variáveis, incluindo sedentarismo. Amostragem por conglomerados. Protocolo: Questionário estruturado, incluindo "Physical Activity Questionaire for Older Children" (PAQ-C); medidas de peso, altura, índice de massa corporal (IMC) e prega cutânea do tríceps (PCT). Análise estatística: Qui-quadrado; correlação linear. RESULTADOS: Nos 1.253 estudantes, com média de idade de 12,4 ± 2,9 anos, sendo 547 do sexo masculino, observou-se uma prevalência de sedentarismo em 93,5 por cento, mais frequente em adolescentes do sexo feminino; não houve associação entre NAF e excesso de peso ou gordura corporal; futebol e dança foram as atividades mais frequentes em meninos e meninas, respectivamente; 60 por cento dos estudantes não têm aulas de Educação Física. Média e mediana de HTV foram, respectivamente, 3,6 e 3 horas; houve associação significante entre maior HTV e obesidade e correlação significante entre NAF e idade (negativa) e entre IMC e PCT (positiva). CONCLUSÃO: O sedentarismo está presente em 93,5 por cento das crianças e adolescentes de Maceió, sendo mais prevalente nos adolescentes e no sexo feminino, não havendo associação ou correlação desta variável com excesso de peso ou gordura corporal; obesidade associou-se a > 3 HTV.


BACKGROUND: Physical inactivity is a predisposing factor to the onset/worsening of other cardiovascular risk factors, particularly obesity. OBJECTIVE: To determine physical activity level (PAL) and daily number of hours of TV (HTV) and the association and/or correlation of these variables with age, gender, economic class, public/private school, overweight and obesity in children and adolescents. METHODS: Cross sectional study, school-based population, public and private education, primary and secondary education. The sample was calculated based on the minimum expected prevalence of several variables, including physical inactivity. Cluster sampling. Protocol: structured questionnaire, including Physical Activity for Older Children Questionnaire (PAQ-C) measurements of weight, height, body mass index (BMI) and triceps skinfold (TSF). Statistical analysis: Chi-square, linear correlation. RESULTS: Among the 1,253 students, averaging 12.4 ± 2.9 years old, of which 549 were male, there was a prevalence of inactivity in 93.5 percent, more commonly found in female adolescents and there was no association between PAL and excess weight or body fat, soccer and dance were the most frequent activities in boys and girls, respectively; 60 percent of students did not have physical education classes. Average and median HTV were respectively 3.6 and 3 hours; there was a significant association between HTV and obesity and significant correlation between PAL and age (negative) and between BMI and TSF (positive). CONCLUSION: Physical inactivity is present in 93.5 percent of children and adolescents from Maceió. It is more commonly found among teenagers and females, with no association or correlation of this variable with excess weight or body fat; obesity was associated with > 3 HTV.


Subject(s)
Adolescent , Child , Female , Humans , Male , Body Composition/physiology , Cardiovascular Diseases/etiology , Exercise/physiology , Sedentary Behavior , Television , Age Distribution , Body Mass Index , Brazil/epidemiology , Cross-Sectional Studies , Obesity/epidemiology , Obesity/etiology , Risk Factors , Sex Distribution , Sex Factors , Skinfold Thickness , Social Class
14.
Arq Bras Cardiol ; 95(2): 159-65, 2010 Aug.
Article in English, Portuguese | MEDLINE | ID: mdl-20563518

ABSTRACT

BACKGROUND: Physical inactivity is a predisposing factor to the onset/worsening of other cardiovascular risk factors, particularly obesity. OBJECTIVE: To determine physical activity level (PAL) and daily number of hours of TV (HTV) and the association and/or correlation of these variables with age, gender, economic class, public/private school, overweight and obesity in children and adolescents. METHODS: Cross sectional study, school-based population, public and private education, primary and secondary education. The sample was calculated based on the minimum expected prevalence of several variables, including physical inactivity. Cluster sampling. PROTOCOL: structured questionnaire, including Physical Activity for Older Children Questionnaire (PAQ-C) measurements of weight, height, body mass index (BMI) and triceps skinfold (TSF). STATISTICAL ANALYSIS: Chi-square, linear correlation. RESULTS: Among the 1,253 students, averaging 12.4 ± 2.9 years old, of which 549 were male, there was a prevalence of inactivity in 93.5%, more commonly found in female adolescents and there was no association between PAL and excess weight or body fat, soccer and dance were the most frequent activities in boys and girls, respectively; 60% of students did not have physical education classes. Average and median HTV were respectively 3.6 and 3 hours; there was a significant association between HTV and obesity and significant correlation between PAL and age (negative) and between BMI and TSF (positive). CONCLUSION: Physical inactivity is present in 93.5% of children and adolescents from Maceió. It is more commonly found among teenagers and females, with no association or correlation of this variable with excess weight or body fat; obesity was associated with ≥ 3 HTV.


Subject(s)
Body Composition/physiology , Cardiovascular Diseases/etiology , Exercise/physiology , Sedentary Behavior , Television , Adolescent , Age Distribution , Body Mass Index , Brazil/epidemiology , Child , Cross-Sectional Studies , Female , Humans , Male , Obesity/epidemiology , Obesity/etiology , Risk Factors , Sex Distribution , Sex Factors , Skinfold Thickness , Social Class
15.
Arq. bras. cardiol ; 94(6): 714-719, jun. 2010. tab
Article in English, Portuguese | LILACS | ID: lil-550686

ABSTRACT

FUNDAMENTO: Excessos de peso e de gordura corporal são atualmente reconhecidos como os maiores determinantes da elevação da pressão arterial em crianças e adolescentes. OBJETIVO: Identificar associação e correlação entre obesidade - identificada por meio da circunferência da cintura (CC), da prega cutânea do tríceps (PCT) e do índice de massa corporal (IMC) - pressão arterial elevada (PAE) em crianças e adolescentes. MÉTODOS: Estudo epidemiológico transversal, de base populacional escolar, em crianças e adolescentes de ambos os sexos, com idades entre 7 e 17 anos, selecionados aleatoriamente. Protocolo: questionário estruturado; medidas de peso, altura, espessura da prega tricipital, circunferência da cintura, pressão arterial; diagnóstico de obesidade por meio de IMC, PCT e CC; diagnóstico de PAE. Análise estatística: qui-quadrado. RESULTADOS: Foram avaliados 1.253 estudantes (547 do sexo masculino, média de idade 12,4 ± 2,9 anos), e identificou-se uma prevalência de obesidade (IMC, PCT, CC), respectivamente, de 13,7 por cento, 14,8 por cento e 9,3 por cento. A PAE foi identificada em 7,7 por cento dos jovens. Houve associação significante de obesidade (IMC, PCT, CC) com PAE (*p < 0,0001). Observou-se correlação forte (*p < 0,01) entre CC e IMC; moderada entre CC e PCT, CC e PAS, IMC e PAS (*p < 0,01); fraca entre PAD e CC, PCT e IMC, e entre PAS e PCT (*p < 0,05). CONCLUSÃO: A associação e correlação significantes entre PAE e excesso de gordura corporal por qualquer dos métodos utilizados estabelecem a importância de sua utilização na avaliação de crianças e adolescentes, com vistas à prevenção da HAS nessa faixa etária, sugerindo-se, para isso, a utilização do IMC associado a, pelo menos, um outro método antropométrico.


BACKGROUND: Excess weight and body fat are currently recognized as the major determinants of high blood pressure in children and adolescents. OBJECTIVE: To identify the relationship between obesity - identified by waist circumference (WC), triceps skinfold thickness (TSF) and body mass index (BMI) - high blood pressure (HBP) in children and adolescents. METHODS: A cross-sectional epidemiological study based on school population in children and adolescents of both sexes, aged between 7 and 17 years, randomly selected. Protocol: a structured questionnaire; measures of weight, height, triceps skinfold thickness, waist circumference, blood pressure, diagnosis of obesity through BMI, TSF thickness and waist circumference; diagnosis of HBP. Statistical analysis: Chi-square. RESULTS: A total of 1,253 students (547 males, mean age 12.4 ± 2.9 years), were assessed. A prevalence of obesity (BMI, TSF thickness, WC) of 13.7 percent, 14,8 percent and 9.3 percent respectively were identified. HBP was identified in 7.7 percent of young people. There was a significant association between obesity (BMI, TSF thickness, WC) with HBP (*p < 0.0001). There was a strong correlation (*p < 0.01) between WC and BMI, a moderate correlation between WC and TSF thickness, WC and SBP, BMI and SBP (*p < 0.01); weak correlation between DBP and WC, TSF thickness and BMI, and between SBP and TSF thickness (*p < 0.05). CONCLUSION: The significant correlation and association between HBP and excess body fat by any of the methods used establish the importance of its use in evaluating children and adolescents, aiming at preventing hypertension in this age group, suggesting, for this, the use of BMI associated to at least another anthropometric method.


Subject(s)
Adolescent , Child , Female , Humans , Male , Hypertension/etiology , Obesity/complications , Blood Pressure Determination , Body Weights and Measures , Brazil/epidemiology , Chi-Square Distribution , Cross-Sectional Studies , Hypertension/epidemiology , Obesity/epidemiology , Prevalence , Risk Factors
16.
Rev Assoc Med Bras (1992) ; 56(2): 192-6, 2010.
Article in Portuguese | MEDLINE | ID: mdl-20498994

ABSTRACT

OBJECTIVE: To establish prevalence of overweight and obesity in children and adolescents from the city of Maceió, Alagoas, Brazil, and investigate the association of risk of overweight and obesity with gender, age and type of school. METHODS: This was a cross-sectional study. Students between 7 and 17 years of age were selected from 396 public and private schools of Maceió. After randomization, data were collected by questionnaire. Weight and height were measured (body mass index = weight:height2). Overweight and obesity were defined, respectively, as body mass index greater than the 85th percentile and equal or greater than the 95th percentile for age and gender. RESULTS: The final sample included 1253 students (706 females). One hundred sixteen students were overweight and fifty six students were obese. Obesity was significantly associated with students between 7 and 9 years of age, when compared to the 10 and 13 year olds (p<0.04) and the 14 and 17 year olds (p<0.02). Private school students were more likely to be overweight (OR=2.2; CI95%:1.36 - 3.32) and more likely to be obese (OR=4.7; CI95%:2.32 - 9.34) than students CONCLUSION: The prevalence of overweight and obesity were, respectively, 9.3% and 4.5%. Overweight and obesity were significantly more frequent among private school students.


Subject(s)
Obesity/epidemiology , Students/statistics & numerical data , Adolescent , Body Mass Index , Brazil/epidemiology , Child , Cross-Sectional Studies , Female , Humans , Male , Overweight/epidemiology , Prevalence , Private Sector , Public Sector , Sex Distribution
17.
Arq Bras Cardiol ; 94(6): 714-9, 2010 Jun.
Article in English, Portuguese | MEDLINE | ID: mdl-20428712

ABSTRACT

BACKGROUND: Excess weight and body fat are currently recognized as the major determinants of high blood pressure in children and adolescents. OBJECTIVE: To identify the relationship between obesity - identified by waist circumference (WC), triceps skinfold thickness (TSF) and body mass index (BMI) - high blood pressure (HBP) in children and adolescents. METHODS: A cross-sectional epidemiological study based on school population in children and adolescents of both sexes, aged between 7 and 17 years, randomly selected. PROTOCOL: a structured questionnaire; measures of weight, height, triceps skinfold thickness, waist circumference, blood pressure, diagnosis of obesity through BMI, TSF thickness and waist circumference; diagnosis of HBP. STATISTICAL ANALYSIS: Chi-square. RESULTS: A total of 1,253 students (547 males, mean age 12.4 +/- 2.9 years), were assessed. A prevalence of obesity (BMI, TSF thickness, WC) of 13.7%, 14,8% and 9.3% respectively were identified. HBP was identified in 7.7% of young people. There was a significant association between obesity (BMI, TSF thickness, WC) with HBP (*p < 0.0001). There was a strong correlation (*p < 0.01) between WC and BMI, a moderate correlation between WC and TSF thickness, WC and SBP, BMI and SBP (*p < 0.01); weak correlation between DBP and WC, TSF thickness and BMI, and between SBP and TSF thickness (*p < 0.05). CONCLUSION: The significant correlation and association between HBP and excess body fat by any of the methods used establish the importance of its use in evaluating children and adolescents, aiming at preventing hypertension in this age group, suggesting, for this, the use of BMI associated to at least another anthropometric method.


Subject(s)
Hypertension/etiology , Obesity/complications , Adolescent , Blood Pressure Determination , Body Weights and Measures , Brazil/epidemiology , Chi-Square Distribution , Child , Cross-Sectional Studies , Female , Humans , Hypertension/epidemiology , Male , Obesity/epidemiology , Prevalence , Risk Factors
18.
Rev. Assoc. Med. Bras. (1992) ; 56(2): 192-196, 2010. tab
Article in Portuguese | LILACS | ID: lil-546938

ABSTRACT

OBJETIVO: Estabelecer a prevalência de sobrepeso e obesidade em crianças e adolescentes de Maceió (Alagoas, Brasil) e verificar associação destes fatores com gênero, idade e tipo de escola. MÉTODOS: Estudo epidemiológico descritivo, transversal. Avaliou jovens de 7 a 17 anos de idade, sorteados das 396 escolas públicas e particulares de Maceió. Após a randomização, os dados foram coletados por meio de questionário e medidas antropométricas (Índice de Massa Corporal = peso: altura²). Sobrepeso e obesidade foram definidos como Índice de Massa Corporal superior ao percentil 85 e igual ou superior ao percentil 95 para idade e sexo, respectivamente. RESULTADOS: A amostra final foi constituída de 1253 estudantes (706 do gênero feminino). Identificados 116 estudantes com sobrepeso e 56 estudantes com obesidade. Houve associação significante entre obesidade e estudantes com idade de sete a nove anos quando comparados com os de 10 a 13 anos (p<0,04) e com os de 14 a 17 anos (p<0,02). Estudantes das escolas particulares apresentaram o dobro de chance de terem sobrepeso (OR=2,2; IC95 por cento:1,36-3,32) e aproximadamente cinco vezes mais chances de apresentarem obesidade (OR=4,7; IC95 por cento:2,32-9,34) em relação aos das escolas públicas. CONCLUSÃO: As prevalências do sobrepeso e obesidade foram de 9,3 por cento e 4,5 por cento respectivamente, sendo significantemente mais elevadas em estudantes das escolas particulares.


OBJECTIVE: To establish prevalence of overweight and obesity in children and adolescents from the city of Maceió, Alagoas, Brazil, and investigate the association of risk of overweight and obesity with gender, age and type of school. METHODS: This was a cross-sectional study. Students between 7 and 17 years of age were selected from 396 public and private schools of Maceió. After randomization, data were collected by questionnaire. Weight and height were measured (body mass index = weight:height2). Overweight and obesity were defined, respectively, as body mass index greater than the 85th percentile and equal or greater than the 95th percentile for age and gender. RESULTS: The final sample included 1253 students (706 females). One hundred sixteen students were overweight and fifty six students were obese. Obesity was significantly associated with students between 7 and 9 years of age, when compared to the 10 and 13 year olds (p<0.04) and the 14 and 17 year olds (p<0.02). Private school students were more likely to be overweight (OR=2.2; CI95 percent:1.36 - 3.32) and more likely to be obese (OR=4.7; CI95 percent:2.32 - 9.34) than students CONCLUSION: The prevalence of overweight and obesity were, respectively, 9.3 percent and 4.5 percent. Overweight and obesity were significantly more frequent among private school students.


Subject(s)
Adolescent , Child , Female , Humans , Male , Obesity/epidemiology , Students/statistics & numerical data , Body Mass Index , Brazil/epidemiology , Cross-Sectional Studies , Overweight/epidemiology , Prevalence , Private Sector , Public Sector , Sex Distribution
19.
Arq. bras. cardiol ; 90(6): e45-e48, jun. 2008. ilus
Article in English, Portuguese | LILACS | ID: lil-485193

ABSTRACT

Trombos móveis no átrio direito são raros e associados a altas taxas de embolia pulmonar e de mortalidade. Neste relato é apresentado um caso de trombo em trânsito nas câmaras direitas, com suspeita clínica de tromboembolismo pulmonar, diagnosticado por ecocardiografia transesofágica, com boa evolução após anticoagulação. São também discutidas suas formas de apresentação, tratamento e evolução.


Emboli in transit in right atrium are rare. When they occur, they are associated to high rate of pulmonary embolism and mortality. This is a case report on an embolus in transit in right chambers, with clinical suspicion of pulmonary thromboembolism. Diagnosis was obtained through transesophageal echocardiography. The patient had a positive response post-anticoagulation. The team discussed presentation forms, treatment and condition development.


Subject(s)
Female , Humans , Middle Aged , Anticoagulants/therapeutic use , Heart Diseases , Pulmonary Embolism , Thrombosis , Echocardiography, Transesophageal , Heart Atria , Heart Diseases/complications , Pulmonary Embolism/drug therapy , Thrombosis/drug therapy , Venous Thrombosis/drug therapy , Venous Thrombosis
20.
Arq Bras Cardiol ; 89(1): 6-10, 2007 Jul.
Article in English, Portuguese | MEDLINE | ID: mdl-17768576

ABSTRACT

OBJECTIVE: To analyze the importance of symptoms as a reason for referral to pediatric cardiologists in the diagnosis of congenital heart diseases (CHD) in the newborn (NB). METHODS: Prospective study on live NB referred for cardiac evaluation, with performance of electrocardiogram, chest radiography and echocardiography. Cardiology consultation was requested by means of a multiple-choice form including signs and symptoms suggestive of CHD. Patent ductus arteriosus (PDA) without clinical and/or hemodynamic consequences was not considered a heart disease. RESULTS: From 1999 to 2002, 358 out of 3716 NB were studied, and 49 cases of CHD and 128 of PDA were found. The prevalence of CHD was 13.2:1000 NB. The main reason for referral to the cardiologist was heart murmur in 256 (72%) NB, of which 39 (15%) had CHD, and in 91% of the 128 cases of PDA. In 14 (4%) NB, the reason for referral was cyanosis, and eight of these patients (57%) had a CHD. Heart failure was the reason for referral in 37 (10%) NB, of whom 17 (46%) had CHD. Arrhythmia, associated congenital malformations, or chromosome disorders were the reasons for referral in 14% of the cases. CONCLUSION: The main reason for referral was detection of a heart murmur on cardiac auscultation. Although cyanosis and heart failure were uncommon reasons for referral, their presence indicated a high probability of the diagnosis of heart disease. Pediatric screening plays a key role in this diagnosis.


Subject(s)
Heart Defects, Congenital/diagnosis , Referral and Consultation , Arrhythmias, Cardiac/diagnosis , Arrhythmias, Cardiac/epidemiology , Brazil/epidemiology , Cardiology , Cyanosis/diagnosis , Cyanosis/epidemiology , Ductus Arteriosus, Patent/diagnosis , Ductus Arteriosus, Patent/epidemiology , Heart Defects, Congenital/epidemiology , Heart Failure/diagnosis , Heart Failure/epidemiology , Heart Function Tests , Heart Murmurs/diagnosis , Heart Murmurs/epidemiology , Humans , Infant, Newborn , Pediatrics , Prevalence , Prospective Studies
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