ABSTRACT
[This corrects the article DOI: 10.1371/journal.pone.0247560.].
ABSTRACT
People living in mining regions are exposed to numerous biological agents by several specific types of transmission mechanisms. This study is designed to describe fatal hantavirus pulmonary syndrome (HPS) cases confirmed by serology and molecular analysis, where a seroprevalence survey was conducted in the gold mining regions of the state of Mato Grosso, in the official Amazon region, Brazil. Two fatal cases of HPS were confirmed in a mining area in the Legal Amazon, where malaria is one of the most important public health problems. A molecular analysis detected the presence of the genome of the Castelo dos Sonhos virus. Out of the 112 blood samples analyzed, five were positive for Plasmodium infection (four P. falciparum and one P. vivax), and four were seropositive for hantavirus, showing a seroprevalence of 3.57%. One of the four miners who was seroreactive for hantavirus concomitantly had P. falciparum infection, which was confirmed by thick blood smear. This manuscript highlights the importance of considering hantavirus pulmonary syndrome as a diagnostic possibility in febrile infection associated with pulmonary manifestations in mining areas where malaria cases are often identified.
Subject(s)
Hantavirus Pulmonary Syndrome/epidemiology , Malaria/epidemiology , Adolescent , Adult , Aged , Brazil/epidemiology , Child , Child, Preschool , Female , Gold , Orthohantavirus/genetics , Hantavirus Pulmonary Syndrome/blood , Hantavirus Pulmonary Syndrome/microbiology , Humans , Infant , Malaria/blood , Malaria/microbiology , Male , Middle Aged , Mining , Phylogeny , Plasmodium/immunology , Seroepidemiologic Studies , Young AdultABSTRACT
A large number of travelers visit the African continent annually for studying, tourism or business reasons. The authors report a case of cervical adenomegaly, hepatomegaly and splenomegaly associated with a two-week history of fever and seropositivity for Bartonella sp in a 22-year-old female patient who returned from South Africa after field work with primates in a wild area.
Subject(s)
Adenoids/pathology , Antibodies, Bacterial/blood , Bartonella Infections/diagnosis , Bartonella/immunology , Travel , Bartonella Infections/drug therapy , Brazil , Female , Fever/microbiology , Humans , South Africa , Young AdultABSTRACT
Um grande número de viajantes visita anualmente, por estudo, turismo ou trabalho o continente africano. Um caso de adenomegalia cervical e hepatoesplenomegalia associado à febre de duas semanas de duração com teste sorológico positivo para Bartonella sp em uma paciente de 22 anos do sexo feminino que retornou da África do Sul após realização de trabalho de campo com primatas em área silvestre é apresentado.
A large number of travelers visit the African continent annually for studying, tourism or business reasons. The authors report a case of cervical adenomegaly, hepatomegaly and splenomegaly associated with a two-week history of fever and seropositivity for Bartonella sp in a 22-year-old female patient who returned from South Africa after field work with primates in a wild area.
