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2.
Otolaryngol Head Neck Surg ; 169(5): 1234-1240, 2023 11.
Article in English | MEDLINE | ID: mdl-37245079

ABSTRACT

OBJECTIVE: To study the surgical and biochemical outcomes in nerve-monitored reoperation or revision surgery for recurrent thyroid cancers. STUDY DESIGN: A single-center retrospective study. SETTING: Tertiary center. METHODS: We identified patients with recurrent papillary thyroid carcinoma (PTC) who underwent reoperation/revision surgery. Study outcomes were surgical complications frequency, recurrence, distant metastasis, and biological complete response (BCR) by comparing preoperative and postoperative thyroglobulin (Tg) levels. RESULTS: Out of 227 patients, 33.9% presented for ≥2 reoperation surgeries. Nineteen (8.4%) had permanent preoperative hypoparathyroidism while 22 patients (9.7%) had preoperative vocal cord paralysis (VCP). Following reoperation surgery, there were 12 cases (5.3%) of permanent hypocalcemia and no cases of unexpected postoperative VCP. BCR was achieved in 31 patients (35.2%) with complete Tg data. Mean preoperative Tg was 47.7 ng/mL and was 19.7 ng/mL postoperatively (p = .003). The cervical nodal recurrence rate after final surgery was 7.0% (n = 16). CONCLUSION: Reoperation surgery for recurrent PTC may help achieve biochemical remission regardless of age or the number of prior surgeries.


Subject(s)
Carcinoma, Papillary , Thyroid Neoplasms , Humans , Thyroid Cancer, Papillary/surgery , Reoperation , Retrospective Studies , Carcinoma, Papillary/surgery , Carcinoma, Papillary/pathology , Neoplasm Recurrence, Local/surgery , Neoplasm Recurrence, Local/pathology , Thyroid Neoplasms/surgery , Thyroid Neoplasms/pathology , Chronic Disease , Thyroidectomy
3.
JAMA Otolaryngol Head Neck Surg ; 149(3): 253-260, 2023 03 01.
Article in English | MEDLINE | ID: mdl-36633855

ABSTRACT

Importance: Identification and preservation of parathyroid glands (PGs) remain challenging despite advances in surgical techniques. Considerable morbidity and even mortality result from hypoparathyroidism caused by devascularization or inadvertent removal of PGs. Emerging imaging technologies hold promise to improve identification and preservation of PGs during thyroid surgery. Observation: This narrative review (1) comprehensively reviews PG identification and vascular assessment using near-infrared autofluorescence (NIRAF)-both label free and in combination with indocyanine green-based on a comprehensive literature review and (2) offers a manual for possible implementation these emerging technologies in thyroid surgery. Conclusions and Relevance: Emerging technologies hold promise to improve PG identification and preservation during thyroidectomy. Future research should address variables affecting the degree of fluorescence in NIRAF, standardization of signal quantification, definitions and standardization of parameters of indocyanine green injection that correlate with postoperative PG function, the financial effect of these emerging technologies on near-term and longer-term costs, the adoption learning curve and effect on surgical training, and long-term outcomes of key quality metrics in adequately powered randomized clinical trials evaluating PG preservation.


Subject(s)
Hypoparathyroidism , Parathyroid Glands , Humans , Parathyroid Glands/diagnostic imaging , Parathyroid Glands/surgery , Thyroid Gland/diagnostic imaging , Thyroid Gland/surgery , Indocyanine Green , Optical Imaging/adverse effects , Optical Imaging/methods , Thyroidectomy/methods , Hypoparathyroidism/etiology
5.
Front Endocrinol (Lausanne) ; 12: 795281, 2021.
Article in English | MEDLINE | ID: mdl-34950109

ABSTRACT

In the past decade, the use of intraoperative neural monitoring (IONM) in thyroid and parathyroid surgery has been widely accepted by surgeons as a useful technology for improving laryngeal nerve identification and voice outcomes, facilitating neurophysiological research, educating and training surgeons, and reducing surgical complications and malpractice litigation. Informing patients about IONM is not only good practice and helpful in promoting the efficient use of IONM resources but is indispensable for effective shared decision making between the patient and surgeon. The International Neural Monitoring Study Group (INMSG) feels complete discussion of IONM in the preoperative planning and patient consent process is important in all patients undergoing thyroid and parathyroid surgery. The purpose of this publication is to evaluate the impact of IONM on the informed consent process before thyroid and parathyroid surgery and to review the current INMSG consensus on evidence-based consent. The objective of this consensus statement, which outlines general and specific considerations as well as recommended criteria for informed consent for the use of IONM, is to assist surgeons and patients in the processes of informed consent and shared decision making before thyroid and parathyroid surgery.


Subject(s)
Consensus Development Conferences as Topic , Informed Consent/standards , Internationality , Monitoring, Intraoperative/standards , Parathyroidectomy/standards , Thyroidectomy/standards , Humans , Monitoring, Intraoperative/adverse effects , Parathyroid Glands/surgery , Parathyroidectomy/adverse effects , Preoperative Care/methods , Preoperative Care/standards , Thyroid Gland/surgery , Thyroidectomy/adverse effects
6.
Head Neck ; 42(9): 2496-2504, 2020 09.
Article in English | MEDLINE | ID: mdl-32530116

ABSTRACT

OBJECTIVE: To survey a large cohort of thyroid cancer survivors from ThyCa on information needs and expectations of their treatment to better understand the pretreatment counseling, information, and support needs of this population. METHODS: Anonymous survey of thyroid cancer survivors. RESULTS: One thousand one hundred twenty-four patients with thyroid cancer participated in the survey. Three hundred sixty-two (37.44%) reported not having had a full understanding of their treatment plan and 407 (46.41%) reported that their thyroid cancer treatment did not conform to expectations. Patients diagnosed at younger ages were significantly more likely to report inadequate understanding of the treatment, failure of treatment to meet expectations, and call for greater attention to psychological well-being. Older patients were more likely to report unexpected effects on speech and swallowing. Regardless of age, patients most frequently called for greater attention to management of energy levels (endorsed by 61% of respondents), psychological well-being (50%), and weight changes (48%). CONCLUSIONS: Improvements are needed in age-specific communication of thyroid cancer diagnosis and treatment.


Subject(s)
Thyroid Neoplasms , Humans , Surveys and Questionnaires , Survivors , Thyroid Neoplasms/surgery , Thyroidectomy , United States/epidemiology
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