ABSTRACT
The platelet aggregation inhibitor ticagrelor, a P2Y12 receptor antagonist, is widely used after angioplasty in patients with acute coronary syndrome. Clinical trial data have shown that it is well tolerated by most patients. We present the case of a 62-year-old woman whose ticagrelor-related asymptomatic and persistent sinus pauses after angioplasty resolved when ticagrelor was replaced with prasugrel.
Subject(s)
Acute Coronary Syndrome/surgery , Angioplasty, Balloon, Coronary/methods , Heart Arrest/chemically induced , Postoperative Complications , Ticagrelor/adverse effects , Acute Coronary Syndrome/drug therapy , Electrocardiography , Female , Heart Arrest/diagnosis , Humans , Middle Aged , Purinergic P2Y Receptor Antagonists/adverse effectsABSTRACT
A 56-year-old healthy male with no obvious risk factors or significant past medical history was admitted to the emergency room with acute ischemic stroke. On his transthoracic echocardiography (TTE), an extremely large thrombus was detected at the apex involving the distal anterior wall. The thrombus was predominantly adherent but with a mobile tip. The patient was subsequently managed with dual antiplatelet therapy. In this report, we present an interesting case of an acute ischemic stroke secondary to a giant left ventricular thrombus in a patient with no past significant cardiac or neurologic medical history.
