ABSTRACT
CASE: The patient, a 21-year-old female Division I track and field athlete, presents with bilateral calf pain, tightness, numbness, and swelling during activity. Initially diagnosed with chronic exertional compartment syndrome (CECS), she underwent bilateral four-compartment fasciotomies. After 4 months, she experienced persistence of some of her prefasciotomy symptoms and was referred to vascular surgery. A fibrous band was compressing the popliteal artery, making the diagnosis of popliteal artery entrapment syndrome (PAES). She underwent bilateral popliteal artery decompressions. She had a successful recovery with no recurrence of numbness, weakness, or pain. CONCLUSION: Recognize that structural PAES may coexist with CECS.
Subject(s)
Chronic Exertional Compartment Syndrome , Popliteal Artery Entrapment Syndrome , Female , Humans , Young Adult , Hypesthesia , Pain , Popliteal Artery/diagnostic imaging , Popliteal Artery/surgeryABSTRACT
Congenital renal arteriovenous fistula (rAVF) is a rare and often underdiagnosed clinical condition. Here, we present a case of a large congenital rAVF in an 81-year-old woman with a right flank bruit and high-output heart failure. The rAVF was successfully treated with percutaneous endovascular coil embolization. Complications included a small right renal hematoma, mild contrast-induced nephropathy, and small right renal infarct in the lower pole. Postoperatively, the patient had complete resolution of symptoms with salvage of the kidney. She has been observed annually for 5 years with computed tomography scan and ultrasound examination.
ABSTRACT
PURPOSE: To present the results of rheolytic pharmacomechanical thrombectomy (PMT) for the management of acute limb ischemia (ALI) as reported in the PEARL Registry (PEripheral Use of AngioJet Rheolytic Thrombectomy with a variety of catheter Lengths). METHODS: A total of 283 patients (mean age 65±13 years; 170 men) presenting with ALI undergoing treatment with the AngioJet System at participating institutions were enrolled in the registry. Rutherford ALI categories included 26% with viable limbs, 38% with marginally threatened limbs, 35% with immediately threatened limbs, and <1% with irreversible damage. Procedure and follow-up data were collected for the calculation of outcomes. To control for patient selection bias, propensity score matching was used to compare outcomes for patients undergoing PMT with or without catheter-directed thrombolysis (CDT). RESULTS: Procedure success was achieved in 235 (83%) of 283 patients. Half of the procedures (147, 52%) were completed without the need for adjunctive CDT. At 12-month follow-up, amputation-free survival and freedom from mortality were 81% and 91%, respectively; 12-month freedom from bleeding requiring transfusion was 91%, and freedom from renal failure was 95%. Subgroup analysis revealed significantly better outcomes in patients without infrapopliteal involvement and those who underwent PMT without CDT. In the matched cohorts, higher rates of procedure success, 12-month amputation-free survival, and 12-month freedom from amputation were observed in the PMT without CDT group (88% vs 74%, p=0.021; 87% vs 72%, p=0.028; 96% vs 81%, p=0.01, respectively). CONCLUSIONS: The results support the use of PMT as a first-line treatment for ALI, providing a rapid reperfusion to the extremity, reduced procedure time, and an acceptable risk profile without compromising limb salvage.
Subject(s)
Arterial Occlusive Diseases/therapy , Ischemia/therapy , Leg/blood supply , Peripheral Vascular Diseases/therapy , Thrombectomy/methods , Thrombolytic Therapy/methods , Acute Disease , Aged , Amputation, Surgical/statistics & numerical data , Angioplasty, Balloon , Combined Modality Therapy , Female , Humans , Male , Propensity Score , Prospective Studies , Registries , Stents , Treatment Outcome , Vascular Access DevicesABSTRACT
PURPOSE: To report procedural and patient outcomes of endovascular treatment for lower-extremity deep vein thrombosis (DVT) with rheolytic thrombectomy (RT). MATERIALS AND METHODS: A total of 32 sites in the United States and Europe enrolled patients with DVT in the Peripheral Use of AngioJet Rheolytic Thrombectomy with a Variety of Catheter Lengths (PEARL) registry. Patient characteristics and outcomes data were collected from consenting patients who underwent rheolytic AngioJet thrombectomy at investigative sites from January 2007 through June 2013. Three hundred twenty-nine patients were enrolled, with 67% of patients undergoing an AngioJet procedure within 14 days of the onset of symptoms. RESULTS: Four treatment approaches using AngioJet thrombectomy were identified: RT without lytic agent in 4% of patients (13 of 329), pharmacomechanical catheter-directed thrombolysis (PCDT) in 35% (115 of 329), PCDT and catheter-directed thrombolysis (CDT) in 52% (172 of 329), and RT in combination with CDT in 9% (29 of 329). Median procedure times for RT alone, PCDT, PCDT/CDT, and RT/CDT were 1.4, 2, 22, and 41 hours, respectively (P < .05, Kruskal-Wallis test). Procedures were completed in less than 24 hours for 73% of patients, with 36% of procedures completed within 6 hours; 86% of procedures required no more than 2 catheter laboratory sessions. The 3-, 6-, and 12-month freedom from rethrombosis rates were 94%, 87%, and 83%, respectively. Major bleeding events occurred in 12 patients (3.6%), but none were related to the AngioJet procedure. CONCLUSIONS: PEARL registry data demonstrate that rheolytic PCDT treatment of DVT is safe and effective, and can potentially reduce the need for concomitant CDT and intensive care.
Subject(s)
Endovascular Procedures/instrumentation , Fibrinolytic Agents/administration & dosage , Lower Extremity/blood supply , Thrombectomy/instrumentation , Thrombolytic Therapy/instrumentation , Vascular Access Devices , Venous Thrombosis/therapy , Adolescent , Adult , Aged , Aged, 80 and over , Disease-Free Survival , Endovascular Procedures/adverse effects , Equipment Design , Europe , Female , Fibrinolytic Agents/adverse effects , Hemorrhage/etiology , Humans , Male , Middle Aged , Prospective Studies , Recurrence , Registries , Risk Factors , Thrombectomy/adverse effects , Thrombolytic Therapy/adverse effects , Time Factors , Treatment Outcome , United States , Venous Thrombosis/diagnosis , Young AdultABSTRACT
PURPOSE: Results are reported from the PEARL I Registry for procedures where a mid-length AngioJet catheter was used for thrombosed hemodialysis arteriovenous grafts and fistulae. METHODS: The PEARL I Registry was a prospective, multicenter, observational database collecting information on the AngioJet procedures for a variety of thrombotic conditions. Patient demographics, procedural information, outcome data, and safety information were collected through 3 months postprocedure on AngioJet procedures. This paper describes the data collected for subjects presenting with hemodialysis access thrombosis. RESULTS: A total of 72 (16%) of the 452 subjects enrolled in the PEARL 1 Registry had thrombosed hemodialysis access sites. Procedural success was reported in 66/72 subjects (92%); surgical interventions were required in 6/72 subjects (8%). There was a statistically significant improvement (p<0.0001) in vessel occlusion from baseline to final angiography. Eighty-eight percent of access sites were patent at the end of the procedure and 97% of vessels showed improved occlusion status of =1 grades. Among prosthetic grafts, 53% (20/38) remained patent at the 3-month follow-up, 18% (7/38) were restenosed, and 29% (11/38) rethrombosed. Among autologous fistulas, 86% (18/21) remained patent without intervention at the 3-month follow-up; 3 fistulas rethrombosed. Four subjects (5%) died; none of the deaths were considered related to the AngioJet device or procedure. CONCLUSIONS: Outcomes from the PEARL I registry corroborate other studies of AngioJet thrombectomy and the overall literature of endovascular thrombectomy procedures. A high procedural success rates with acceptable near-term patency rates and low rates of adverse events are achieved with AngioJet thrombectomy.